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4. The Immediate Intramedullary Nailing Surgery Increased the Mitochondrial DNA Release That Aggravated Systemic Inflammatory Response and Lung Injury Induced by Elderly Hip Fracture
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10. Endotracheal tube-induced sore throat pain and inflammation is coupled to the release of mitochondrial DNA
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11. Involvement of Mitochondrial Disorders in Septic Cardiomyopathy
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15. cfDNA correlates with endothelial damage after cardiac surgery with prolonged cardiopulmonary bypass and amplifies NETosis in an intracellular TLR9-independent manner
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16. Increased toll-like receptor 9 expression is associated with the severity of paraquat-induced lung injury in mice
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17. Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis
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18. Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?
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19. Mitochondrial DNA-induced inflammatory damage contributes to myocardial ischemia reperfusion injury in rats: Cardioprotective role of epigallocatechin
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20. The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness
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21. Diverse Roles of Mitochondria in Ischemic Stroke
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22. Hypoxia, Oxidative Stress and Inflammation
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23. Elevated Cell-Free Mitochondrial DNA in Filtered Plasma Is Associated With HIV Infection and Inflammation
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24. Danger Signals in the ICU
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25. Mitochondrial DNA induces Foley catheter related bladder inflammation via Toll-like receptor 9 activation
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26. Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases
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27. Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response
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28. Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage
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29. Epigallocatechin gallate attenuates mitochondrial DNA-induced inflammatory damage in the development of ventilator-induced lung injury
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30. The Role of Mitophagy in Innate Immunity
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31. The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases
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32. PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.
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33. The Evolving Erythrocyte: Red Blood Cells as Modulators of Innate Immunity
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34. Extracellular DAMPs in Plants and Mammals: Immunity, Tissue Damage and Repair
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35. Mitochondrial peptides cause proinflammatory responses in the alveolar epithelium via FPR-1, MAPKs, and AKT: a potential mechanism involved in acute lung injury
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36. Alcohol and Cannabis Use Alter Pulmonary Innate Immunity
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37. Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness
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39. Endotracheal intubation results in acute tracheal damage induced by mtDNA/TLR9/NF‐κB activity
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40. DNA methylation processes in atheosclerotic plaque
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41. Influenza-induced immune suppression to methicillin-resistant Staphylococcus aureus is mediated by TLR9
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42. Socioeconomic Deprivation, Adverse Childhood Experiences and Medical Disorders in Adulthood: Mechanisms and Associations
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43. Complement factor H regulates retinal development and its absence may establish a footprint for age related macular degeneration
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44. Optineurin inhibits NLRP3 inflammasome activation by enhancing mitophagy of renal tubular cells in diabetic nephropathy
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45. Insulin Promotes Wound Healing by Inactivating NFkβP50/P65 and Activating Protein and Lipid Biosynthesis and alternating Pro/Anti-inflammatory Cytokines Dynamics
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46. Role of mitochondrial dysfunction on rheumatic diseases
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47. Circulating mitochondria in organ donors promote allograft rejection
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48. Mitochondria are the powerhouses of immunity
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49. Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression.
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50. Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL
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51. Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis
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52. Metformin as a Radiation Modifier; Implications to Normal Tissue Protection and Tumor Sensitization
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53. Ribosomal DNA as DAMPs Signal for MCF7 Cancer Cells
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55. Scavenger Receptor SCARA5 Acts as an HMGB1 Recognition Molecule Negatively Involved in HMGB1-Mediated Inflammation in Fish Models
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56. Mitochondria and Inflammation: Cell Death Heats Up.
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57. Accumulation of Circulating Cell-Free CpG-Enriched Ribosomal DNA Fragments on the Background of High Endonuclease Activity of Blood Plasma in Schizophrenic Patients
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58. Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency
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59. Optimized clinical practice for superaged patients with hip fracture: significance of damage control and enhanced recovery program
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60. Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle
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61. Circulating cell-free mitochondrial DNA as the probable inducer of early endothelial dysfunction in the prediabetic patient
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62. The Involvement of Danger-Associated Molecular Patterns in the Development of Immunoparalysis in Cardiac Arrest Patients
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63. Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis
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64. Mitochondrial DNA has a pro-inflammatory role in AMD
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65. Danger in the Intensive Care Unit
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66. Mitochondrial DNA in the regulation of innate immune responses.
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67. Plasma Mitochondrial DNA—a Novel DAMP in Pediatric Sepsis
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68. Circulating Mitochondrial DNA as Predictor of Mortality in Critically Ill Patients
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69. The Alarmin Properties of DNA and DNA-associated Nuclear Proteins
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70. Priming of human neutrophils is necessary for their activation by extracellular DNA
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71. Mitochondrial DNA and TLR9 Signaling Is Not Involved in Mechanical Ventilation-Induced Inflammation
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72. The diagnostic and prognostic value of systems biology research in major traumatic and thermal injury: a review
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73. Plasma mitochondrial DNA levels were independently associated with lung injury in elderly hip fracture patients
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74. Plasma mtDNA copy numbers are associated with GSTK1 expression and inflammation in type 2 diabetes
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75. Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3-mediated activation of superoxide dismutase 2
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76. Preeclamptic patient-derived circulating cell-free DNA activates the production of inflammatory cytokines via toll-like receptor 9 signalling in the human placenta
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77. Neuroprotective potential of azilsartan against cerebral ischemic injury: Possible involvement of mitochondrial mechanisms
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78. Mitochondrial alarmins are tissue mediators of ventilator-induced lung injury and ARDS.
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79. Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis
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80. Deoxyribonuclease Reduces Tissue Injury and Improves Survival After Hemorrhagic Shock
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82. Mitochondrial DNA, oxidants, and innate immunity
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83. Noncanonical Functions of the Human Ribosomal Repeat
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84. Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort.
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85. Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction
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88. Epigenetic control of atherosclerosis via DNA methylation: A new therapeutic target?
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89. An evolutionary, or “Mitocentric” perspective on cellular function and disease
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90. Toll-like receptor 9 and the inflammatory response to surgical trauma and cardiopulmonary bypass
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91. In utero inflammatory challenge induces an early activation of the hepatic innate immune response in late gestation fetal sheep
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92. The Role of Danger Associated Molecular Patterns in Human Fetal Membrane Weakening
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93. The NLRP3 Inflammasome as a Critical Actor in the Inflammaging Process
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94. Early surgery increases mitochondrial DNA release and lung injury in a model of elderly hip fracture and chronic obstructive pulmonary disease
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95. Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity.
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96. Rewiring Mitochondrial Metabolism for CD8+ T Cell Memory Formation and Effective Cancer Immunotherapy
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99. Mitochondrial DNA drives noncanonical inflammation activation via cGAS–STING signaling pathway in retinal microvascular endothelial cells
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100. Cell-free mitochondrial DNA increases granulosa cell apoptosis and reduces aged oocyte blastocyst development in the mouse
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101. Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature
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102. The role of mitophagy in innate immune responses triggered by mitochondrial stress.
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103. Emerging role of mitochondria in airborne particulate matter-induced immunotoxicity
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104. Mitochondrial Damage-Associated Molecular Patterns Exacerbate Lung Fluid Imbalance Via the Formyl Peptide Receptor-1 Signaling Pathway in Acute Lung Injury
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106. The role of bacterial DNA containing CpG motifs in diseases
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107. Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation
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108. Aging: All roads lead to mitochondria
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109. Role of Mitochondria-Derived Danger Signals Released After Injury in Systemic Inflammation and Sepsis.
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110. The role of mitophagy in pulmonary sepsis.
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111. Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren’s syndrome
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112. Novel Insights and Current Evidence for Mechanisms of Atherosclerosis: Mitochondrial Dynamics as a Potential Therapeutic Target
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113. Toll-Like Receptor 9-Mediated Neuronal Innate Immune Reaction Is Associated with Initiating a Pro-Regenerative State in Neurons of the Dorsal Root Ganglia Non-Associated with Sciatic Nerve Lesion
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114. Mitochondrial DNA plays an important role in lung injury induced by sepsis
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115. Mitochondria-Induced Immune Response as a Trigger for Neurodegeneration: A Pathogen from Within
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116. Ageing mechanisms that contribute to tissue remodeling in lung disease
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117. Through DNA sensors and hidden mitochondrial effects of SARS-CoV-2
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118. Mitochondrial RNA , a new trigger of the innate immune system
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119. Dulaglutide improves muscle function by attenuating inflammation through OPA-1-TLR-9 signaling in aged mice
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120. Downregulation of mitochondrial biogenesis by virus infection triggers antiviral responses by cyclic GMP-AMP synthase
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121. DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia
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122. Role of Damage-Associated Molecular Pattern/Cell Death Pathways in Vaccine-Induced Immunity
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123. Role of Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology
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124. Extrusion of mitochondria: Garbage clearance or cell-cell communication signals?
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125. On the Origin of Neutrophil Extracellular Traps in COVID-19
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126. Mitochondrial DNA on Tumor-Associated Macrophages Polarization and Immunity
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127. Systemic inflammatory response syndrome is triggered by mitochondrial damage (Review)
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128. Nucleic Acid Sensing Pathways in DNA Repair Targeted Cancer Therapy
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129. Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer
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130. Intravitreal injection of mitochondrial DNA induces cell damage and retinal dysfunction in rats
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132. Associations between Cell-Free Mitochondrial DNA and Inflammation, and Their Clinical Implications for Patients on Hemodialysis: A Prospective Multicenter Cohort Study
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133. Therapeutic Targeting of Innate Immune Receptors Against SARS-CoV-2 Infection
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134. A Glimpse of Inflammation and Anti-Inflammation Therapy in Diabetic Kidney Disease
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135. Cell-free mitochondrial DNA quantification in ischemic stroke patients for non-invasive and real-time monitoring of disease status
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136. Chromatin-Associated Molecular Patterns (CAMPs) in sepsis
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137. Role of released mitochondrial DNA in acute lung injury
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138. Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy
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139. Glaucomatous optic neuropathy: Mitochondrial dynamics, dysfunction and protection in retinal ganglion cells
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140. Mitochondrial Contribution to Inflammation in Diabetic Kidney Disease
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141. Mitophagy bridges DNA sensing with metabolic adaption to expand lung cancer stem‐like cells
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142. An Updated Review of Mitochondrial Transplantation as a Potential Therapeutic Strategy Against Cerebral Ischemia and Cerebral Ischemia/Reperfusion Injury
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143. Mitochondria as novel mediators linking gut microbiota to atherosclerosis that is ameliorated by herbal medicine: A review
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144. Clustering of serum biomarkers involved in post-aneurysmal subarachnoid hemorrhage (aSAH) complications
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145. Metformin counters oxidative stress and mitigates adverse effects of radiation exposure: An overview
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146. Mitochondrial mechanisms in Alzheimer’s disease: quest for therapeutics
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147. The role of neutrophil extracellular traps and proinflammatory damage-associated molecular patterns in idiopathic inflammatory myopathies
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148. Mitochondria-derived cell-to-cell communication
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149. Self‐Propelled Proteomotors with Active Cell‐Free mtDNA Clearance for Enhanced Therapy of Sepsis‐Associated Acute Lung Injury
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150. Mitochondrial DNA and Inflammation in Alzheimer’s Disease
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151. Mitochondrial Damage-Associated Molecular Patterns and Metabolism in the Regulation of Innate Immunity
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152. Mitochondrial nucleic acids in innate immunity and beyond
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153. N-acetyltransferase and inflammation: Bridging an unexplored niche
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154. Activation of innate immune receptor TLR9 by mitochondrial DNA plays essential roles in the chemical long-term depression of hippocampal neurons
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155. Mitochondrial damage‐associated molecular patterns: A new insight into metabolic inflammation in type 2 diabetes mellitus
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156. Mesenchymal Stem Cells Reduce the Extracellular Mitochondrial DNA-Mediated TLR9 Activation in Neonatal Hyperoxia-Induced Lung Injury
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