- Importance of epigenetic changes in cancer etiology, pathogenesis, clinical profiling, and treatment: What can be learned from hematologic malignancies?
Lorella Vecchio et al, 2013, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer CrossRef - Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute myeloid leukemia
Hamid Ali Nagi Al-Jamal et al, 2015, BMC Cancer CrossRef - Decitabine Downregulates TIGAR to Induce Apoptosis and Autophagy in Myeloid Leukemia Cells
Lanzhu Li et al, 2021, Oxidative Medicine and Cellular Longevity CrossRef - Pharmacologic reversion of epigenetic silencing of the PRKD1promoter blocks breast tumor cell invasion and metastasis
Sahra Borges et al, 2013, Breast Cancer Research CrossRef - Turning on the Radio: Epigenetic Inhibitors as Potential Radiopriming Agents
Bryan Oronsky et al, 2016, Biomolecules CrossRef - DNA Demethylation Switches Oncogenic ΔNp63 to Tumor Suppressive TAp63 in Squamous Cell Carcinoma
Zuzana Pokorna et al, 2022, Frontiers in Oncology CrossRef - Generalist in allogeneic hematopoietic stem cell transplantation for MDS or AML: Epigenetic therapy
Guancui Yang et al, 2022, Frontiers in Immunology CrossRef - Combination therapy with epigenetic-targeted and chemotherapeutic drugs delivered by nanoparticles to enhance the chemotherapy response and overcome resistance by breast cancer stem cells
Shi-Yong Li et al, 2015, Journal of Controlled Release CrossRef - Changes in the physicochemical properties of fish cell membranes during cellular senescence
Akifumi Shiomi et al, 2020, Bioscience, Biotechnology, and Biochemistry CrossRef - Canonical and new generation anticancer drugs also target energy metabolism
Sara Rodríguez-Enríquez et al, 2014, Archives of Toxicology CrossRef - Role of reactive oxygen species in myelodysplastic syndromes
Qiangan Jing et al, 2024, Cellular & Molecular Biology Letters CrossRef - Decitabine Enhances Acute Myeloid Leukemia Cell Apoptosis through SH3BGRL Upregulation
Xiuzhen Tong et al, 2022, Anti-Cancer Agents in Medicinal Chemistry CrossRef - EVI1 promotes metastasis by downregulating TIMP2 in metastatic colon and breast cancer cells
null Pradeepa et al, 2022, The International Journal of Biochemistry & Cell Biology CrossRef - Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways
Jessica Dittmann et al, 2020, Cell Death & Differentiation CrossRef - Licochalcone B induces apoptosis of human oral squamous cell carcinoma through the extrinsic- and intrinsic-signaling pathways
HANA OH et al, 2016, International Journal of Oncology CrossRef - Decitabine promotes apoptosis in mesenchymal stromal cells isolated from patients with myelodysplastic syndromes by inducing reactive oxygen species generation
Lihua Wang et al, 2019, European Journal of Pharmacology CrossRef - Trailing TRAIL Resistance in Human Breast Adenocarcinoma Cells with Trichostatin A and Zebularine
Siew Ching Ngai et al, 2023, Anti-Cancer Agents in Medicinal Chemistry CrossRef - Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
Sonia Abou Najem et al, 2019, Current Molecular Pharmacology CrossRef - 5-aza-2′-deoxycytidine promotes migration of acute monocytic leukemia cells via activation of CCL2-CCR2-ERK signaling pathway
Xia Xiao et al, 2017, Molecular Medicine Reports CrossRef - Epigenetic therapy: azacytidine and decitabine in acute myeloid leukemia
Stephan R. Bohl et al, 2018, Expert Review of Hematology CrossRef - Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models
Verona Buocikova et al, 2022, Biomedicine & Pharmacotherapy CrossRef - Synergistic cytotoxicity of decitabine and YM155 in leukemia cells through upregulation of SLC35F2 and suppression of MCL1 and survivin expression
Jing-Ting Chiou et al, 2024, Apoptosis CrossRef - Decitabine Induces Delayed Reactive Oxygen Species (ROS) Accumulation in Leukemia Cells and Induces the Expression of ROS Generating Enzymes
Tamer E. Fandy et al, 2014, Clinical Cancer Research CrossRef - Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations
Julia Jabs et al, 2017, Molecular Systems Biology CrossRef - Decitabine as a First-Line Treatment for Older Adults Newly Diagnosed with Acute Myeloid Leukemia
Hyunsung Park et al, 2017, Yonsei Medical Journal CrossRef - Synergistic inhibitory effects of low‑dose decitabine in combination with bortezomib in the AML cell line Kasumi‑1
Vassiliki Mpakou et al, 2021, Experimental and Therapeutic Medicine CrossRef