1. The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition
    Michael Schnekenburger et al, 2018, Molecules CrossRef
  2. Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway
    Brian J. Philips et al, 2020, Oncotarget CrossRef
  3. Recent Progress on the Discovery of Sirt2 Inhibitors for the Treatment of Various Cancers
    Ting Wang et al, 2019, Current Topics in Medicinal Chemistry CrossRef
  4. Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway
    Jie Zhu et al, 2018, Frontiers in Pharmacology CrossRef
  5. Assessment of Pharmacological Interactions between SIRT2 Inhibitor AGK2 and Paclitaxel in Different Molecular Subtypes of Breast Cancer Cells
    Anna Wawruszak et al, 2022, Cells CrossRef
  6. HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network
    Maria I. Lazaro-Pena et al, 2022, Frontiers in Aging CrossRef
  7. Discovery and Characterization of R/S-N-3-Cyanophenyl-N′-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines
    Michael Schnekenburger et al, 2017, Journal of Medicinal Chemistry CrossRef
  8. Sirtuin 2 (SIRT2): Confusing Roles in the Pathophysiology of Neurological Disorders
    Xiuqi Chen et al, 2021, Frontiers in Neuroscience CrossRef
  9. Human cytomegalovirus modulates mTORC1 to redirect mRNA translation within quiescently infected monocytes
    Michael J. Miller et al, 2024, Journal of Virology CrossRef
  10. Anticancer activities of a benzimidazole compound through sirtuin inhibition in colorectal cancer
    Yi Jer Tan et al, 2018, Future Medicinal Chemistry CrossRef
  11. Epigenetic Control Using Small Molecules in Cancer
    Tomohiro Kozako et al, 2020, Approaching Complex Diseases CrossRef
  12. Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer
    Wenjing Ma et al, 2018, Cancer Biology & Therapy CrossRef
  13. The bifunctional roles of sirtuins and their therapeutic potential in cancer
    Yeuan Ting Lee et al, 2021, Sirtuin Biology in Cancer and Metabolic Disease CrossRef
  14. Asiatic acid suppresses neuroinflammation in BV2 microgliaviamodulation of the Sirt1/NF-κB signaling pathway
    Yisong Qian et al, 2018, Food & Function CrossRef
  15. Chikusetsusaponin V Inhibits LPS-Activated Inflammatory Responses via SIRT1/NF-κB Signaling Pathway in RAW264.7 Cells
    Qin Yuan et al, 2018, Inflammation CrossRef
  16. Inhibition of sirtuins 1 and 2 impairs cell survival and migration and modulates the expression of P-glycoprotein and MRP3 in hepatocellular carcinoma cell lines
    María Paula Ceballos et al, 2018, Toxicology Letters CrossRef
  17. Biochemical mechanism and biological effects of the inhibition of silent information regulator 1 (SIRT1) by EX-527 (SEN0014196 or selisistat)
    Sylvain Broussy et al, 2020, Journal of Enzyme Inhibition and Medicinal Chemistry CrossRef
  18. Regulation of HSF1 protein stabilization: An updated review
    Chao Huang et al, 2018, European Journal of Pharmacology CrossRef
  19. Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer
    Vincenzo Carafa et al, 2019, International Journal of Molecular Sciences CrossRef