Effect of dietary phytochemicals on cancer development (review)

  • Authors:
    • A R Waladkhani
    • M R Clemens
  • View Affiliations

  • Published online on: April 1, 1998     https://doi.org/10.3892/ijmm.1.4.747
  • Pages: 747-800
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Abstract

Vegetables, fruits, and whole grains contain a wide variety of phytochemicals that have the potential to modulate cancer development. There are many biologically plausible reasons why consumption of plant foods might slow or prevent the appearance of cancer. These include the presence in plant foods of such potentially anticarcinogenic substances as carotenoids, chlorophyll, flavonoids, indole, isothiocyanate, polyphenolic compounds, protease inhibitors, sulfides, and terpens. The specific mechanisms of action of most phytochemicals in cancer prevention are not yet clear but appear to be varied. Considering the large number and variety of dietary phytochemicals, their interactive effects on cancer risk may be extremely difficult to assess. Phytochemicals can inhibit carcinogenesis by inhibiting phase I enzymes, and induction of phase II enzymes, scavenge DNA reactive agents, suppress the abnormal proliferation of early, preneoplastic lesions, and inhibit certain properties of the cancer cell.

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Apr 1998
Volume 1 Issue 4

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Waladkhani A and Waladkhani A: Effect of dietary phytochemicals on cancer development (review). Int J Mol Med 1: 747-800, 1998
APA
Waladkhani, A., & Waladkhani, A. (1998). Effect of dietary phytochemicals on cancer development (review). International Journal of Molecular Medicine, 1, 747-800. https://doi.org/10.3892/ijmm.1.4.747
MLA
Waladkhani, A., Clemens, M."Effect of dietary phytochemicals on cancer development (review)". International Journal of Molecular Medicine 1.4 (1998): 747-800.
Chicago
Waladkhani, A., Clemens, M."Effect of dietary phytochemicals on cancer development (review)". International Journal of Molecular Medicine 1, no. 4 (1998): 747-800. https://doi.org/10.3892/ijmm.1.4.747