Journal Articles

Review Open Access

The role of hypoxia in inflammatory disease (Review)

John Biddlestone, Daniel Bandarra, Sonia Rocha

Pages: 859-869 Published online on: 27 January 2015
Article Open Access

Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant

Bo-Yun Jang, Hyung Don Ryoo, Jaekyoung Son, Kyung-Chul Choi, Dong-Myoung Shin, Sang-Wook Kang, Min-Ji Kang

Pages: 870-876 Published online on: 25 February 2015
Article Open Access

MicroRNA profiles following metformin treatment in a mouse model of non-alcoholic steatohepatitis

Akiko Katsura, Asahiro Morishita, Hisakazu Iwama, Joji Tani, Teppei Sakamoto, Miwa Tatsuta, Yuka Toyota, Koji Fujita, Kiyohito Kato, Emiko Maeda, Takako Nomura, Hisaaki Miyoshi, Hirohito Yoneyama, Takashi Himoto, Shintaro Fujiwara, Hideki Kobara, Hirohito Mori, Toshiro Niki, Masafumi Ono, Mitsuomi Hirashima, Tsutomu Masaki

Pages: 877-884 Published online on: 06 February 2015
Article Open Access

Lentivirus-mediated RNAi knockdown of the gap junction protein, Cx43, attenuates the development of vascular restenosis following balloon injury

Xiao-Jian Han, Min Chen, Tao Hong, Ling-Yu Zhu, Dan  He, Jiu-Geng Feng, Li-Ping Jiang

Pages: 885-892 Published online on: 23 January 2015
Article Open Access

Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li

Pages: 893-900 Published online on: 18 February 2015
Article Open Access

Effects of baicalin on collagen Ι and collagen ΙΙΙ expression in pulmonary arteries of rats with hypoxic pulmonary hypertension

Panpan Liu, Shuangquan Yan, Mayun Chen, Ali Chen, Dan Yao, Xiaomei Xu, Xueding Cai, Liangxing Wang, Xiaoying Huang

Pages: 901-908 Published online on: 25 February 2015
Article Open Access

The proliferative effects of Pyropia yezoensis peptide on IEC-6 cells are mediated through the epidermal growth factor receptor signaling pathway

Min-Kyeong Lee, In-Hye Kim, Youn-Hee Choi, Jeong-Wook Choi, Young-Min Kim, Taek-Jeong Nam

Pages: 909-914 Published online on: 26 February 2015
Article Open Access

An ethanol root extract of Cynanchum wilfordii containing acetophenones suppresses the expression of VCAM-1 and ICAM-1 in TNF-α-stimulated human aortic smooth muscle cells through the NF-κB pathway

Hyun Jung Koo, Eun-Hwa Sohn, Suhkneung Pyo, Han Goo Woo, Dae Won Park, Young-Min Ham, Seon-A Jang, Soo-Yeong Park, Se Chan Kang

Pages: 915-924 Published online on: 26 February 2015
Article Open Access

Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes

Nieves González, Antonio Martín-Duce, Félix Martínez-Arrieta, Zaida Moreno-Villegas, Sergio Portal-Núñez, Raúl Sanz, Jesús Egido

Pages: 925-931 Published online on: 04 February 2015
Article Open Access

Palmitate induces endoplasmic reticulum stress and autophagy in mature adipocytes: Implications for apoptosis and inflammation

Jiajing Yin, Yufan Wang, Liping Gu, Nengguang Fan, Yuhang Ma, Yongde Peng

Pages: 932-940 Published online on: 30 January 2015
Article Open Access

CAP1 is overexpressed in human epithelial ovarian cancer and promotes cell proliferation

Minhui Hua, Sujuan Yan, Yan Deng, Qinghua Xi, Rong Liu, Shuyun Yang, Jian Liu, Chunhui Tang, Yingying Wang, Jianxin Zhong

Pages: 941-949 Published online on: 04 February 2015
Article Open Access

Characterization of three alternative transcripts of the BRCA1 gene in patients with breast cancer and a family history of breast and/or ovarian cancer who tested negative for pathogenic mutations

Gaetana Gambino, Mariella Tancredi, Elisabetta Falaschi, Paolo Aretini, Maria Adelaide Caligo

Pages: 950-956 Published online on: 16 February 2015
Article Open Access

Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages

Sin-Hye Park, Ji Hun Paek, Daekeun Shin, Jae-Yong Lee, Soon Sung Lim, Young-Hee Kang

Pages: 957-965 Published online on: 12 February 2015
Article

Enhanced expression of centromere protein F predicts clinical progression and prognosis in patients with prostate cancer

Yang-Jia Zhuo, Ming Xi, Yue-Ping Wan, Wei Hua, Yuan-Ling Liu, Song Wan, Yu-Lin Zhou, Hong-Wei Luo, Shu-Lin Wu, Wei-De Zhong, Chin-Lee Wu

Pages: 966-972 Published online on: 30 January 2015
Article

Melatonin improves experimental colitis with sleep deprivation

Young-Sook Park, Sook-Hee Chung, Seong-Kyu Lee, Ja-Hyun Kim, Jun-Bong Kim, Tae-Kyun Kim, Dong-Shin Kim, Haing-Woon Baik

Pages: 979-986 Published online on: 27 January 2015
Article

Rhododendron album Blume inhibits iNOS and COX-2 expression in LPS-stimulated RAW264.7 cells through the downregulation of NF-κB signaling

Ji-Won Park, Ok-Kyoung Kwon, Jung-Hee Kim, Sei-Ryang Oh, Jae-Hong Kim, Jin-Hyub Paik, Bambang Marwoto, Rifatul Widjhati, Fifit Juniarti, Doddy Irawan, Kyung-Seop Ahn

Pages: 987-994 Published online on: 25 February 2015
Article

PLGA/poloxamer nanoparticles loaded with EPAS1 siRNA for the treatment of pancreatic cancer in vitro and in vivo

Xinting Pan, Qingyun Zhu, Yunbo Sun, Liandi Li, Yunpeng Zhu, Zhihui Zhao, Jianxin Zuo, Wei Fang, Kun Li

Pages: 995-1002 Published online on: 11 February 2015
Article

The role of Toll-like receptor 3 and 4 in regulating the function of mesenchymal stem cells isolated from umbilical cord

Li Zhang, Dan Liu, Dan Pu, Yanwen Wang, Li Li, Yanqi He, Yalun Li, Lei Li, Zhixin Qiu, Shuang Zhao, Weimin Li

Pages: 1003-1010 Published online on: 19 February 2015
Article

Berberine regulates melanin synthesis by activating PI3K/AKT, ERK and GSK3β in B16F10 melanoma cells

Young Chan Song, Yonghee Lee, Hyeong Mi Kim, Moo Yeol Hyun, Yun Young Lim, Kye Yong Song, Beom Joon Kim

Pages: 1011-1016 Published online on: 26 February 2015
Article

Epidermal growth factor improves the migration and contractility of aged fibroblasts cultured on 3D collagen matrices

Daehwan Kim, So Young Kim, Seog Kyun Mun, Sangmyung Rhee, Beom Joon Kim

Pages: 1017-1025 Published online on: 03 February 2015
Article

Sodium tanshinone IIA sulfonate attenuates the transforming growth factor-β1-induced differentiation of atrial fibroblasts into myofibroblasts in vitro

Le Yang, Jin Hu, Hong-Zhen Hao, Zhao Yin, Gang Liu, Xiao-Jing Zou

Pages: 1026-1032 Published online on: 02 February 2015
Article

Downregulation of microRNA-1 in esophageal squamous cell carcinoma correlates with an advanced clinical stage and its overexpression inhibits cell migration and invasion

Li Yao, Yi Zhang, Qiao Zhu, Xinyi Li, Shaojun Zhu, Li Gong, Xiujuan Han, Miao Lan, Shanqu Li, Wei Zhang, Yanhong Li

Pages: 1033-1041 Published online on: 09 February 2015
Article

Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway

So Young Kim, Moo Yeol Hyun, Kyung Chan Go, Christos C. Zouboulis, Beom Joon Kim

Pages: 1042-1050 Published online on: 12 February 2015
Article

Transplantation of human umbilical cord-derived mesenchymal stems cells for the treatment of Becker muscular dystrophy in affected pedigree members

Pang Li, Kai Cui, Bo Zhang, Zhendan Wang, Yangyang Shen, Xiangyu Wang, Jianbo Zhang, Feng Tong, Sheng Li

Pages: 1051-1057 Published online on: 30 January 2015
Article

TBX20 loss-of-function mutation contributes to double outlet right ventricle

Yun Pan, Rui Geng, Ning Zhou, Gui-Fen Zheng, Hong Zhao, Juan Wang, Cui-Mei Zhao, Xing-Biao Qiu, Yi-Qing Yang, Xing-Yuan Liu

Pages: 1058-1066 Published online on: 22 January 2015
Article

Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro

Yan Wang, Minghao Nie, Yanhong Lu, Rui Wang, Jin Li, Bin Yang, Mingyang Xia, Haiyang Zhang, Xiurong Li

Pages: 1067-1073 Published online on: 09 February 2015
Article

Integrin-β1 regulates chondrocyte proliferation and apoptosis through the upregulation of GIT1 expression

Long-Qiang Zhang, Guang-Zong Zhao, Xiao-Yan Xu, Jun Fang, Jing-Ming Chen, Ji-Wen Li, Xue-Jian Gao, Li-Juan Hao, Yun-Zhen Chen

Pages: 1074-1080 Published online on: 26 February 2015
Article

BAD-mediated apoptotic pathway is associated with human cancer development

Xiaomang B. Stickles, Douglas C. Marchion, Elona Bicaku, Entidhar Al Sawah, Forough Abbasi, Yin Xiong, Nadim Bou Zgheib, Bernadette M. Boac, Brian C. Orr, Patricia L. Judson, Amy Berry, Ardeshir Hakam, Robert M. Wenham, Sachin M. Apte, Anders E. Berglund, Johnathan M. Lancaster

Pages: 1081-1087 Published online on: 05 February 2015
Article

Dual effect of metformin on growth inhibition and oestradiol production in breast cancer cells

S. Rice, L. Pellat, A. Ahmetaga, G. Bano, H. D. Mason, S. A. Whitehead

Pages: 1088-1094 Published online on: 25 February 2015
Review

Mitogen-activated protein kinase phosphatase-1: A critical phosphatase manipulating mitogen-activated protein kinase signaling in cardiovascular disease (Review)

Chang-Yi Li, Ling-Chao Yang, Kai Guo, Yue-Peng Wang, Yi-Gang Li

Pages: 1095-1102 Published online on: 18 February 2015
Article

Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction

Shuhua Chen, Jie Yang, Hong Xiang, Wei Chen, Hua Zhong, Guoping Yang, Ting Fang, Hao Deng, Hong Yuan, Alex F. Chen, Hongwei Lu

Pages: 1103-1108 Published online on: 12 February 2015
Article

Selective PCAF inhibitor ameliorates cognitive and behavioral deficits by suppressing NF-κB-mediated neuroinflammation induced by Aβ in a model of Alzheimer's disease

Soo-Yeon Park, Mi-Jeong Kim, Young Jun Kim, Yoo-Hyun Lee, Donghyuk Bae, Sunoh Kim, Younghwa Na, Ho-Geun Yoon

Pages: 1109-1118 Published online on: 12 February 2015
Article

miR-29c is downregulated in the ectopic endometrium and exerts its effects on endometrial cell proliferation, apoptosis and invasion by targeting c-Jun

Mei Long, Xiaohui Wan, Xiaolin La, Xiaoyun Gong, Xia Cai

Pages: 1119-1125 Published online on: 27 January 2015
Article

Saikosaponin a, an active compound of Radix Bupleuri, attenuates inflammation in hypertrophied 3T3-L1 adipocytes via ERK/NF-κB signaling pathways

Sung Ok Kim, Ji Yeoung Park, Seo Young Jeon, Chea Ha Yang, Mi Ryeo Kim

Pages: 1126-1132 Published online on: 06 February 2015
Article

Qing Hua Chang Yin inhibits the LPS-induced activation of the IL-6/STAT3 signaling pathway in human intestinal Caco-2 cells

Xiao Ke, Guanghong Hu, Wenyi Fang, Jintuan Chen, Xin Zhang, Chunbo Yang, Jun Peng, Youqin Chen, Thomas J. Sferra

Pages: 1133-1137 Published online on: 28 January 2015
Correction Open Access

[Corrigendum] Alterations in gene expression during sexual differentiation in androgen receptor knockout mice induced by environmental endocrine disruptors

Dehong Liu, Liping Shen, Yonglin Tao, Ying Kuang, Lei Cai, Dan Wang, Meiduo He, Xuebo Tong, Shuguang Zhou, Jie Sun, Chenchen Shi, Chunxiao Wang, Yi Wu

Pages: 1147-1147 Published online on: 11 February 2015
Journal Cover

April-2015
Volume 35 Issue 4

Print ISSN: 1107-3756
Online ISSN: 1791-244X

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