nPKCdelta a new therapeutic marker for melanoma metastasis? (Review).

  • Authors:
    • C A La Porta
  • Corresponding author:
  • View Affiliations

  • Published online on: Monday, May 1, 2000
  • Pages: 467-538 DOI: 10.3892/ijmm.5.5.467

Abstract

Melanoma metastasis is almost uniformly fatal. The identification of signal transduction as crucial effectors for tumorigenesis suggests modalities of gene therapy as well as design of specific drugs. the possible use of nPKCdelta as a therapeutic target is reviewed and discussed. Motivated by recent results, we propose a model in which nPKCdelta modulates melanin synthesis as well as metastasis.
Journal Cover

May 2000
Volume 5 Issue 5

Print ISSN: 1107-3756
Online ISSN:1791-244X

2014 Impact Factor: 2.088
Ranked #22/123 Medicine Research and Experimental
(total number of cites)

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APA
La Porta, C. (2000). nPKCdelta a new therapeutic marker for melanoma metastasis? (Review).. International Journal of Molecular Medicine, 5, 467-538. http://dx.doi.org/10.3892/ijmm.5.5.467
MLA
La Porta, C."nPKCdelta a new therapeutic marker for melanoma metastasis? (Review).". International Journal of Molecular Medicine 5.5 (2000): 467-538.
Chicago
La Porta, C."nPKCdelta a new therapeutic marker for melanoma metastasis? (Review).". International Journal of Molecular Medicine 5, no. 5 (2000): 467-538. http://dx.doi.org/10.3892/ijmm.5.5.467