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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2010 Volume 26 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance

Ali A. Bonab, Edward A. Carter, Kasie Paul, Masao Kaneki, Yong-Ming Yu, Ronald G. Tompkins, Alan J. Fischman
Pages: 311-316
Published online on: 01 September 2010

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Article

Changes in the endogenous BMP expression during redifferentiation of chondrocytes in 3D cultures

Christian Albrecht, Werner Schlegel, Philipp Bartko, Peter Eckl, Tamara Jagersberger, Vilmos Vécsei, Stefan Marlovits
Pages: 317-323
Published online on: 01 September 2010

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Article

Transforming growth factor β1 produced in autocrine/paracrine manner affects the morphology and function of mesothelial cells and promotes peritoneal carcinomatosis

Di Na, Zhi-Dong Lv, Fu-Nan Liu, Yan Xu, Cheng-Gang Jiang, Zhe Sun, Zhi-Feng Miao, Feng Li, Hui-Mian Xu
Pages: 325-332
Published online on: 01 September 2010

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Article

Genomic instability and DNA ploidy are linked to DNA copy number aberrations of 8p23 and 22q11.23 in gastric cancers

Shigeto Kawauchi, Tomoko Furuay, Tetsuji Uchiyama, Atsushi Adachi, Takae Okada, Motonao Nakao, Atsunori Oga, Kenichiro Uchida, Kohsuke Sasaki
Pages: 333-339
Published online on: 01 September 2010

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Article

Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells

Kathy Ka-Wai Auyeung, Nga-Lai Mok, Ching-Man Wong, Chi-Hin Cho, Joshua Ka-Shun Ko
Pages: 341-349
Published online on: 01 September 2010

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Article

Anti-asthmatic activities in mycelial extract and culture filtrate of Cordyceps sphecocephala J201

Jin-Chul Heo, Sung-Hee Nam, Dong-Yoon Nam, Jong-Guk Kim, Kwang-Gil Lee, Joo-Hong Yeo, Cheol-Sik Yoon, Chul-Hong Park, Sang-Han Lee
Pages: 351-356
Published online on: 01 September 2010

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Article

Apelin plays a catabolic role on articular cartilage: In vivo and in vitro studies

Peng-Fei Hu, Wei-Ping Chen, Jing-Li Tang, Jia-Peng Bao, Li-Dong Wu
Pages: 357-363
Published online on: 01 September 2010

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Article

GATA-4 promotes the differentiation of P19 cells into cardiac myocytes

De-Liang Hu, Fu-Kun Chen, Yao-Qiu Liu, Yan-Hui Sheng, Rong Yang, Xiang-Qing Kong, Ke-Jiang Cao, Hai-Tao Gu, Ling-Mei Qian
Pages: 365-372
Published online on: 01 September 2010

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Article

TAT-Hsp27 promotes adhesion and migration of murine dental papilla-derived MDPC-23 cells through β1 integrin-mediated signaling

Jong-Hwan Park, Ji-Hye Yoon, Young-Sin Lim, Ho-Keel Hwang, Soo-A Kim, Sang-Gun Ahn, Jung-Hoon Yoon
Pages: 373-378
Published online on: 01 September 2010

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Article

Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression

Chun-Yuan Cheng, Chin-Cheng Su
Pages: 379-385
Published online on: 01 September 2010

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Article

Antithrombin III reduces collagen-stimulated granule secretion of PDGF-AB and the release of soluble CD40 ligand from human platelets

Tomoaki Doi, Seiji Adachi, Rie Matsushima-Nishiwaki, Hisaaki Kato, Yukiko Enomoto, Hideo Natsume, Kenji Kato, Jun Mizutani, Takanobu Otsuka, Haruhiko Tokuda, Shigeru Akamatsu, Toru Iwama, Osamu Kozawa, Shinji Ogura
Pages: 387-392
Published online on: 01 September 2010

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Article

Am80 induces neuronal differentiation in a human neuroblastoma NH-12 cell line

Hideo Shiohira, Akira Kitaoka, Hiromi Shirasawa, Munechika Enjoji, Manabu Nakashima
Pages: 393-399
Published online on: 01 September 2010

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Article

Deoxyschisandrin inhibits H2O2-induced apoptotic cell death in intestinal epithelial cells through nuclear factor-κB

Bon-Hee Gu, Nguyen Van Minh, Sun-Hee Lee, Sung-Won Lim, Young-Mi Lee, Kang-Soo Lee, Dae-Ki Kim
Pages: 401-406
Published online on: 01 September 2010

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Article Open Access

Selective aldosterone blocker ameliorates the progression of non-alcoholic steatohepatitis in rats

Ryuichi Noguchi, Hitoshi Yoshiji, Yasuhide Ikenaka, Kosuke Kaji, Yusaku Shirai, Yosuke Aihara, Masaharu Yamazaki, Tadashi Namisaki, Mitsuteru Kitade, Junichi Yoshii, Koji Yanase, Hideto Kawaratani, Tatsuhiro Tsujimoto, Hiroshi Fukui
Pages: 407-413
Published online on: 01 September 2010

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Article

The immune modulation of Clara cell-10 in human peripheral monocytes and dendritic cells

Jung Min Yoon, Kyu-Hwa Lee, Sang Min Lee, Jae-Jun Lim, Seok-Chul Yang, Chul-Gyu Yoo, Choon-Taek Lee, Sung Koo Han, Young-Soo Shim, Young Whan Kim
Pages: 415-423
Published online on: 01 September 2010

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Article

Clinical significance of tumor markers in detection of recurrent hepatocellular carcinoma after radiofrequency ablation

Tetsuya Beppu, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Satoko Kusagawa, Keiichiro Nojiri, Junichiro Tanaka, Norihiko Yamamoto, Yoshiyuki Takei, Haruyuki Takaki, Junji Uraki, Atsuhiro Nakatsuka, Koichiro Yamakado, Kan Takeda
Pages: 425-433
Published online on: 01 September 2010

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Article

The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcγRIIIa-48L/R/H polymorphism

Marzena Lenart, Elzbieta Trzyna, Magdalena Rutkowska, Karolina Bukowska-Strakova, Anna Szaflarska, Anna Pituch-Noworolska, Antoni Szczepanik, Marek Zembala, Maciej Siedlar
Pages: 435-442
Published online on: 01 September 2010

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Journal Cover
July-2026 Volume 58 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review)

Yanqin Fan, Hongtu Hu, Jing Cheng
Article Number: 202
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury

Yin Yang, Chunyang Guo, Bo Liao, Junjun Cao, Chen Liang, Xijing He
Article Number: 201
Published online on: 25 May 2026

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Article Open Access

Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 200
Published online on: 22 May 2026

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Article Open Access

Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome

Jinghui Zhai, Yueming Zhang, Jiawei Gong, Li Fu, Sixi Zhang
Article Number: 199
Published online on: 22 May 2026

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Article Open Access

Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning

Qiming Xu, Chunjing Xu, Ziyang Liu, Jianrao Lu, Jing Hu, Lin Liao
Article Number: 198
Published online on: 21 May 2026

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Article Open Access

CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats

Tianzhu Liu, Longqing Zhang, Wei Mei
Article Number: 197
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Article Number: 196
Published online on: 20 May 2026

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Article Open Access

Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice

Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang
Article Number: 195
Published online on: 20 May 2026

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Article Open Access

Endothelial NOX4‑driven oxidative stress inhibition reverses HtrA1 deficiency‑induced blood‑brain barrier disruption and cognitive impairment

Shi-Na Song, Jun-Ying Wu, Mao-Mei Song, Xiao-Feng Li, Jian-Ming Wang, Wen-Hui Jia, Chang-Xin Li, Sui-Yi Xu
Article Number: 194
Published online on: 19 May 2026

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Review Open Access

Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)

Sen Chen, Xiaofei Cui
Article Number: 193
Published online on: 19 May 2026

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Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review)

Zhenjun Xi, Xiaodong Li, Chunhui Yang, Li Wang, Jingxin Mao, Qianqian Liu, Chang Liu, Qian Li, Yuanfang Hou, Jie Wan, Chengzhuo Yang, Feiji Sun, Chao Yu, Miao Wang, Baocheng Yuan, Yongsheng Liu, Qing Hu, Li Zhang, Xuemei Li, Xiaobing Li
Article Number: 192
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Hiroshi Fukui
Article Number: 191
Published online on: 18 May 2026

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Review Open Access

Autophagy and metabolic homeostasis: Exploration in obesity‑related metabolic diseases (Review)

Chenglin Lu, Xiangyu Qi, Yuting Tong, Peng Lu, Dandan Luo, Qingbo Guan, Chunxiao Yu
Article Number: 190
Published online on: 14 May 2026

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Review Open Access

Primary cilia dysfunction: A critical driver of metabolic diseases (Review)

Xiaojing Wang, Yi Jin, Kejia Xie, Pengfei Yao, Liguo Song, Hongdan Liu, Yanjie Tan
Article Number: 189
Published online on: 14 May 2026

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Review Open Access

Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review)

Xigang Ma, Yongsen Zhao
Article Number: 188
Published online on: 14 May 2026

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Article Open Access

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway

Yiwei Zhao, Zechao Qu, Lin Liu, Yong Zhang, Xiaohao Wang, Bo Zhang, Yining Gong, Liang Yan
Article Number: 187
Published online on: 13 May 2026

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Correction Open Access

[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong-Hee Kim, Bang-Jin Kim, Seok-Man Kim, Sun-Uk Kim, Buom-Yong Ryu
Article Number: 186
Published online on: 13 May 2026

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Review Open Access

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review)

Guiqing Chen, Hongyan Jia, Kai Zhao, Chang Gao, Yue Liu, Hong Zhu, Dakai Yang, Yun Cai
Article Number: 185
Published online on: 13 May 2026

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Article Open Access

Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Review Open Access

Rab27: Molecular switch of tumor exosome secretion (Review)

Mengtian Tang, Zhongjian Zhu, Huaxin Duan, Shiming Tan, Mengzhou Shen, Xianjie Jiang, Qiu Peng, Linda Oyang, Zongyao Ren, Yujuan Zhou, Qianjin Liao
Article Number: 182
Published online on: 12 May 2026

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Article Open Access

IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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Article Open Access

CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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Correction Open Access

[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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Article Open Access

miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Review Open Access

Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Review Open Access

Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Review Open Access

Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Review Open Access

Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Article Open Access

Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Article Open Access

Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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Journal Cover
August-2026 Volume 58 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis

Qingtao Yang, Wei Li, Qi Yu, Jiang Shi, Lu Yang, Jun Qiao, Xi Wei, Changshi Gu, Fa Sun, Tao Li
Article Number: 217
Published online on: 09 June 2026

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Review Open Access

Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Review Open Access

Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Article Open Access

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

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Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

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Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

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Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
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Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

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[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

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Article Number: 205
Published online on: 28 May 2026

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Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

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Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
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Published online on: 28 May 2026

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