Journal Articles

Article Open Access

Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells

Emi Yamaoka, Eiso Hiyama, Yusuke Sotomaru, Yoshiyuki Onitake, Ikuko Fukuba, Takeshi Sudo, Taijiro Sueda, Keiko Hiyama

Pages: 5-11 Published online on: 03 May 2011
Article Open Access

miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer

Shuichi Tatarano, Takeshi Chiyomaru, Kazumori Kawakami, Hideki Enokida, Hirofumi Yoshino, Hideo Hidaka, Takeshi Yamasaki, Kazuya Kawahara, Kenryu Nishiyama, Naohiko Seki, Masayuki Nakagawa

Pages: 13-21 Published online on: 20 April 2011
Article Open Access

Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo

Takayuki Yamaguchi, Reina Kakefuda, Nobuyuki Tajima, Yoshihiro Sowa, Toshiyuki Sakai

Pages: 23-31 Published online on: 26 April 2011
Article

Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2

Hiromi Tanabe, Kageaki Kuribayashi, Naoki Tsuji, Maki Tanaka, Daisuke Kobayashi, Naoki Watanabe

Pages: 33-40 Published online on: 18 April 2011
Article

Intracellular estrogen receptor-binding fragment-associated antigen 9 exerts in vivo tumor-promoting effects via its coiled-coil region

Yoshihiro Maeyama, Makoto Otsu, Shuji Kubo, Tomoki Yamano, Yasuaki Iimura, Masafumi Onodera, Satoshi Kondo, Yukio Sakiyama, Tadashi Ariga

Pages: 41-49 Published online on: 03 May 2011
Article

High incidence of high-risk HPV in benign and malignant lesions of the larynx

Anaëlle Duray, Géraldine Descamps, Mohammad Arafa, Christine Decaestecker, Myriam Remmelink, Nicolas Sirtaine, Perle Ernoux-Neufcoeur, Eugène Mutijima, Joan Somja, Christophe E. Depuydt, Philippe Delvenne, Sven Saussez

Pages: 51-59 Published online on: 04 May 2011
Article

Urothelial cancer cell response to combination therapy of gemcitabine and TRAIL

Jacob A. Moibi, Allan L. Mak, Bo Sun, Ronald B. Moore

Pages: 61-71 Published online on: 29 April 2011
Article

Endosialin is expressed in high grade and advanced sarcomas: Evidence from clinical specimens and preclinical modeling

Cecile Rouleau, Robert Smale, Yao-Shi Fu, Guodong Hui, Fei Wang, Elizabeth Hutto, Robert Fogle, Craig M. Jones, Roy Krumbholz, Stephanie Roth, Maritza Curiel, Yi Ren, Rebecca G. Bagley, Gina Wallar, Glenn Miller, Steven Schmid, Bruce Horten, Beverly A. Teicher

Pages: 73-89 Published online on: 29 April 2011
Article

FLT-PET may not be a reliable indicator of therapeutic response in p53-null malignancy

Sharyn I. Katz, Lanlan Zhou, Thomas A. Ferrara, Wenge Wang, Patrick A. Mayes, Charles D. Smith, Wafik S. El-Deiry

Pages: 91-100 Published online on: 29 April 2011
Article

Autophagy and cell death signaling following dietary sulforaphane act independently of each other and require oxidative stress in pancreatic cancer

Patrick Naumann, Franco Fortunato, Hanswalter Zentgraf, Markus W. Büchler, Ingrid Herr, Jens Werner

Pages: 101-109 Published online on: 29 April 2011
Article

Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells

Wendell S. Fortson, Shubhalaxmi Kayarthodi, Yasuo  Fujimura, Huali Xu, Roland  Matthews, William E. Grizzle, Veena   N. Rao, Ganapathy K. Bhat, E. Shyam P. Reddy

Pages: 111-119 Published online on: 21 April 2011
Article
Article

Methylation-related mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women

Nisreen Al-Moghrabi, Abeer J.S. Al-Qasem, Abdelilah Aboussekhra

Pages: 129-135 Published online on: 29 April 2011
Article

Human umbilical cord blood-derived mesenchymal stem cells improve glucose homeostasis in rats with liver cirrhosis

Kyung Hee Jung, Yun-Kyung Uhm, Yun Jeong Lim, Sung-Vin Yim

Pages: 137-143 Published online on: 28 April 2011
Article

Substrate optimization and clinical validation of reporter peptides for MS-based protease profiling in serum specimens: A new approach for diagnosis of malignant disease

Diego Yepes, Anette Jacob, Marc Dauber, Victor Costina, Ralf Hofheinz, Michael Neumaier, Peter Findeisen

Pages: 145-154 Published online on: 18 April 2011
Article

FBXO31 determines poor prognosis in esophageal squamous cell carcinoma

Ryunosuke Kogo, Koshi Mimori, Fumiaki Tanaka, Shizuo Komune, Masaki Mori

Pages: 155-159 Published online on: 28 April 2011
Article

Human complement factor H is a novel diagnostic marker for lung adenocarcinoma

Tiantian Cui, Yuan Chen, Thomas Knösel, Linlin Yang, Kristin Zöller, Kerstin Galler, Alexander Berndt, Michael Mihlan, Peter F. Zipfel, Iver Petersen

Pages: 161-168 Published online on: 18 April 2011
Article

MALAT-1: A long non-coding RNA and its important 3' end functional motif in colorectal cancer metastasis

Chuan Xu, Minhui Yang, Jie Tian, Xiaoyan Wang, Zuguo Li

Pages: 169-175 Published online on: 15 April 2011
Article

Catechol estrogens as biomarkers for mammary gland cancer

Gloria M. Calaf, Fernando Garrido

Pages: 177-183 Published online on: 15 April 2011
Article

The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma

Christian Cordes, Robert Häsler, Christian Werner, Tibor  Görögh, Christoph Röcken, Lena Hebebrand, W. Martin Kast, Markus  Hoffmann, Stefan Schreiber, Petra Ambrosch

Pages: 185-191 Published online on: 14 April 2011
Article

Ultraviolet exposure of melanoma cells induces fibroblast activation protein-α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F. Gilmore, Oliver Seifert

Pages: 193-202 Published online on: 13 April 2011
Article

Overexpression of α1,6-fucosyltransferase in hepatoma enhances expression of Golgi phosphoprotein 2 in a fucosylation-independent manner

Sayuri Kawamoto, Kenta Moriwaki, Tsutomu Nakagawa, Mika Terao, Shinichiro Shinzaki, Naoko Yamane-Ohnuki, Mitsuo Satoh, Anand S. Mehta, Timothy M. Block, Eiji Miyoshi

Pages: 203-208 Published online on: 14 April 2011
Article

Monoamine carboxylate transporters are involved in BI-1-associated cancer metastasis in HT1080 colon fibrosarcoma cells

Geum-Hwa Lee, Han-Jung Chae, Hyung-Ryong Kim

Pages: 209-216 Published online on: 29 April 2011
Article

Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways

Chin-Chung Lin, Chao-Lin Kuo, Mau-Hwa Lee, Kuang-Chi Lai, Jing-Pin Lin, Jai-Sing Yang, Chun-Shu Yu, Chi-Cheng Lu, Jo-Hua Chiang, Fu-Shin Chueh, Jing-Gung Chung

Pages: 217-224 Published online on: 03 May 2011
Article

Molecular mechanisms of the antimetastatic activity of nuclear clusterin in prostate cancer cells

Roberta M. Moretti, Stefania Mai, Marina Montagnani Marelli, Federica Rizzi, Saverio Bettuzzi, Patrizia Limonta

Pages: 225-234 Published online on: 03 May 2011
Article

Phosphorylation of β-catenin results in lack of β-catenin signaling in melanoma

Silke Kuphal, Anja Katrin Bosserhoff

Pages: 235-243 Published online on: 03 May 2011
Article

Lentivirally engineered dendritic cells activate AFP-specific T cells which inhibit hepatocellular carcinoma growth in vitro and in vivo

Yang Liu, Lisa H. Butterfield, Xiaohui Fu, Zhenshun Song, Xiaoping Zhang, Chongde Lu, Guanghui Ding, Mengchao Wu

Pages: 245-253 Published online on: 13 April 2011
Article Open Access

Bone metastases detection by circulating biomarkers: OPG and RANK-L

Laura Mercatali, Toni Ibrahim, Emanuele Sacanna, Emanuela Flamini, Emanuela Scarpi, Daniele Calistri, Marianna Ricci, Patrizia Serra, Rossana Ricci, Wainer Zoli, Yibin Kang, Dino Amadori

Pages: 255-261 Published online on: 13 April 2011
Article

Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes

Norihiko Suzuki, Tomohiro Emura, Masakazu Fukushima

Pages: 263-270 Published online on: 13 April 2011
Article

Vandetanib inhibits both VEGFR-2 and EGFR signalling at clinically relevant drug levels in preclinical models of human cancer

Sandra R. Brave, Rajesh Odedra, Neil H. James, Neil R. Smith, Gayle B. Marshall, Kerry L. Acheson, Dawn Baker, Zoe Howard, Lynsay Jackson, Kirsty Ratcliffe, Anna Wainwright, Susan C. Lovick, D. Mark Hickinson, Robert W. Wilkinson, Simon T. Barry, Georgina Speake, Anderson J. Ryan

Pages: 271-278 Published online on: 29 April 2011
Article

Artesunate enhances TRAIL-induced apoptosis in human cervical carcinoma cells through inhibition of the NF-κB and PI3K/Akt signaling pathways

Oranuch Thanaketpaisarn, Pornthip Waiwut, Hiroaki Sakurai, Ikuo Saiki

Pages: 279-285 Published online on: 28 April 2011
Article

Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad antibody responses in humans, a RAYS-based analysis

Axel Mischo, Nina Bubel, Jonathan S. Cebon, Panagiotis Samaras, Ulf Petrausch, Frank Stenner-Liewen, Niklaus G. Schaefer, Boris Kubuschok, Christoph Renner, Andreas Wadle

Pages: 287-294 Published online on: 06 May 2011
Journal Cover

Cover Legend PDF

July 2011
Volume 39 Issue 1

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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