Journal Articles

Article Open Access

Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas

Atsuo Yoshino, Shinya Tashiro, Akiyoshi Ogino, Kazunari Yachi, Takashi Ohta, Takao Fukushima, Takao Watanabe, Yoichi Katayama, Yutaka Okamoto, Emiko Sano, Kouhei Tsumoto

Pages: 529-542 Published online on: 06 June 2011
Article Open Access

Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma

B. Martinez-Poveda, V. Gomez, M. Alcaide-German, S. Perruca, S. Vazquez, L. E. Alba, O. Casanovas, M. L. Garcia-Bermejo, L. Peso, B. Jimenez

Pages: 543-552 Published online on: 09 June 2011
Article Open Access

Safety and effectiveness of a new enzyme-targeting radiosensitization treatment (KORTUC II) for intratumoral injection for low-LET radioresistant tumors

Yasuhiro Ogawa, Kei Kubota, Hironobu Ue, Michiko Tadokoro, Rina  Matsui, Tomoaki Yamanishi, Norihiko Hamada, Shinji Kariya, Akihito  Nishioka, Hideki Nakajima, Masahito Tarutani, Shigetoshi Sano

Pages: 553-560 Published online on: 06 June 2011
Article Open Access

Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells

Michihiro Kamigaki, Tamito Sasaki, Masahiro Serikawa, Motoki Inoue, Kenso Kobayashi, Hiroshi Itsuki, Tomoyuki Minami, Masanobu Yukutake, Akihito Okazaki, Takashi Ishigaki, Yasutaka Ishii, Keiichi Kosaka, Kazuaki Chayama

Pages: 561-568 Published online on: 17 June 2011
Article

YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer

Kentaro Yamanaka, Mari Nakata, Naoki Kaneko, Hiroshi Fushiki, Aya Kita, Takahito Nakahara, Hiroshi Koutoku, Masao Sasamata

Pages: 569-575 Published online on: 14 June 2011
Article

Early in vitro passages of breast cancer cells are differentially susceptible to retinoids and differentially express RARβ isoforms

Xinjian Peng, Albert Green, Anne Shilkaitis, Yonghua Zhu, Laura Bratescu, Konstantin Christov

Pages: 577-583 Published online on: 07 June 2011
Article

BCR-ABL- and Ras-independent activation of Raf as a novel mechanism of Imatinib resistance in CML

Julia Hentschel, Ignacio Rubio, Melanie Eberhart, Christina Hipler, Jana Schiefner, Katrin Schubert, Ivan F. Loncarevic, Ute Wittig, Aria Baniahmad, Ferdinand von Eggeling

Pages: 585-591 Published online on: 01 June 2011
Article

Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer

Masanori Ii, Hiroyuki Yamamoto, Hiroaki Taniguchi, Yasushi Adachi, Mayumi Nakazawa, Hirokazu Ohashi, Tokuma Tanuma, Yasutaka Sukawa, Hiromu Suzuki, Shigeru Sasaki, Kohzoh Imai, Yasuhisa Shinomura

Pages: 593-599 Published online on: 20 May 2011
Article

The cell death response to the ROS inducer, cobalt chloride, in neuroblastoma cell lines according to p53 status

Christophe Stenger, Thomas Naves, Mireille Verdier, Marie-Helene Ratinaud

Pages: 601-609 Published online on: 16 June 2011
Article

The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor

Kuan-Tin Chen, Mann-Jen Hour, Shih-Chang Tsai, Jing-Gung Chung, Sheng-Chu Kuo, Chi-Cheng Lu, Yu-Jen Chiu, Yi-Hsuan Chuang, Jai-Sing Yang

Pages: 611-619 Published online on: 08 June 2011
Article

Integrated analysis of copy number and loss of heterozygosity in primary breast carcinomas using high-density SNP array

Ho Ching Ching, Rakesh Naidu, Mun Kein Seong, Yip  Cheng Har, Nur Aishah Mohd Taib

Pages: 621-633 Published online on: 15 June 2011
Article

18α-glycyrrhetinic acid targets prostate cancer cells by down-regulating inflammation-related genes

Aditya V. Shetty, Sivasakthivel Thirugnanam, Gajalakshmi Dakshinamoorthy, Abhilash Samykutty, Guoxing Zheng, Aoshuang Chen, Maarten C. Bosland, André Kajdacsy-Balla, Munirathinam Gnanasekar

Pages: 635-640 Published online on: 31 May 2011
Article

Antitumor activity of NRC-AN-019 in a pre-clinical breast cancer model

Christopher S. Gondi­­, Bharathi Gorantla, A. K.S. Bhujanga Rao, K. Amala, M. U.R. Naidu, K. V. Jogi, G. Venkat Ramana, Praveen C. Myneni, Ajit Junnarkar, Jasti S. Rao

Pages: 641-648 Published online on: 14 June 2011
Article

Nuclear localization of phosphorylated ERK1 and ERK2 as markers for the progression of ovarian cancer

Abraham Amsterdam, Elias Shezen, Calanit Raanan, Letizia Schreiber, Diana Prus, Yasmin Slilat, Alon Ben-Arie, Rony Seger

Pages: 649-656 Published online on: 17 June 2011
Article

Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion

Kaori Koga, Mikiko Aoki, Tetsuro Sameshima, Makoto Hamasaki, Nagayasu  Egawa, Motoharu Seiki, Bryan P. Toole, Junji Suzumiya, Kazuki Nabeshima

Pages: 657-664 Published online on: 31 May 2011
Article

Downregulation of microRNA-211 is involved in expression of preferentially expressed antigen of melanoma in melanoma cells

Eiichi Sakurai, Chihaya Maesawa, Masahiko Shibazaki, Shinji Yasuhira, Hiroki Oikawa, Masayuki Sato, Kanako Tsunoda, Yuichi Ishikawa, Ayano Watanabe, Kazuhiro Takahashi, Toshihide Akasaka, Tomoyuki Masuda

Pages: 665-672 Published online on: 16 June 2011
Article Open Access

DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status

Birgitte L. Adamsen, Katherine L. Kravik, Paula M. De Angelis

Pages: 673-682 Published online on: 14 June 2011
Article Open Access

Hypermethylation of promoter regions of the APC1A and p16INK4a genes in relation to prognosis and tumor characteristics in cervical cancer patients

Zarah M. Löf-Öhlin, Bengt Sorbe, Sten Wingren, Torbjörn K. Nilsson

Pages: 683-688 Published online on: 14 June 2011
Article Open Access

Mesenchymal stem cells and carcinoma-associated fibroblasts sensitize breast cancer cells in 3D cultures to kinase inhibitors

Angela Dittmer, Alexander Fuchs, Ilka Oerlecke, Benjamin Leyh, Susann Kaiser, John W.M. Martens, Jana Lützkendorf, Lutz Müller, Jürgen Dittmer

Pages: 689-696 Published online on: 09 June 2011
Article

Opioids increase bladder cancer cell migration via bradykinin B2 receptors

Despoina Vassou, George Notas, Anastassia Hatzoglou, Elias Castanas, Marilena Kampa

Pages: 697-707 Published online on: 03 June 2011
Article

Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks

Alastair G. Lowrie, Paul Dickinson, Nicholas Wheelhouse, Grant D. Stewart, Alan J. Ross, Thorsten Forster, James A. Ross

Pages: 709-718 Published online on: 03 June 2011
Article

Aberrant DNA methylation of T-cell leukemia, homeobox 3 modulates cisplatin sensitivity in bladder cancer

Yasuhiro Tada, Akira Yokomizo, Masaki Shiota, Toshiyuki Tsunoda, Christoph Plass, Seiji Naito

Pages: 727-733 Published online on: 23 May 2011
Article

Pharmacological induction of leukotriene B4-12-hydroxydehydrogenase suppresses the oncogenic transformation of human hepatoma HepG2 cells

Lai Wei, Jie Liu, X. Chris Le, Yifan Han, Yao Tong, Allan S.Y. Lau, Jianhui Rong

Pages: 735-745 Published online on: 16 June 2011
Article

Anticancer mechanism of equol in 7,12-dimethylbenz(a)anthracene-treated animals

Eun Jeong Choi, Gun-Hee Kim

Pages: 747-754 Published online on: 06 June 2011
Journal Cover

Cover Legend PDF

September 2011
Volume 39 Issue 3

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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