Journal Articles
Review
Lipogenesis in cancer progression (Review)
Catherine Mounier, Lamia Bouraoui, Eric Rassart
Pages: 485-492 Published online on: 13 May 2014
Review
The unique protein kinase Cη: Implications for breast cancer (Review)
Deepanwita Pal, Alakananda Basu
Pages: 493-498 Published online on: 19 May 2014
Review
ALK inhibitors and advanced non-small cell lung cancer (Review)
Antonio Rossi, Paolo Maione, Paola Claudia Sacco, Assunta Sgambato, Francesca Casaluce, Marianna Luciana Ferrara, Giovanni Palazzolo, Fortunato Ciardiello, Cesare Gridelli
Pages: 499-508 Published online on: 29 May 2014
Review
Diagnostic and therapeutic issues for patients with advanced non‑small cell lung cancer harboring anaplastic lymphoma kinase rearrangement: European vs. US perspective (Review)
Massimo Di Maio, Filippo De Marinis, Fred R. Hirsch, Cesare Gridelli
Pages: 509-515 Published online on: 21 May 2014
Review
Emerging targeted therapies for melanoma treatment (Review)
Angela Russo, Bartolomea Ficili, Saverio Candido, Franca Maria Pezzino, Claudio Guarneri, Antonio Biondi, Salvatore Travali, James A. McCubrey, Demetrios A. Spandidos, Massimo Libra
Pages: 516-524 Published online on: 03 June 2014
Review
The non-reverse transcriptase activity of the human telomerase reverse transcriptase promotes tumor progression (Review)
Yong Qin, Hong Guo, Bo Tang, Shi-Ming Yang
Pages: 525-531 Published online on: 28 May 2014
Article
Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer
Irene Zinonos, Ke-Wang Luo, Agatha Labrinidis, Vasilios Liapis, Shelley Hay, Vasilios Panagopoulos, Mark Denichilo, Chun-Hay Ko, Grace Gar-Lee Yue, Clara Bik-San Lau, Wendy Ingman, Vladimir Ponomarev, Gerald J. Atkins, David M. Findlay, Andrew C.W. Zannettino, Andreas Evdokiou
Pages: 532-540 Published online on: 27 May 2014
Article
Collagen triple helix repeat containing 1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation and motility
Masahiko Tameda, Kazushi Sugimoto, Katsuya Shiraki, Norihiko Yamamoto, Ryuji Okamoto, Masanobu Usui, Masaaki Ito, Yoshiyuki Takei, Tsutomu Nobori, Takahiro Kojima, Hideaki Suzuki, Masako Uchida, Kazuhiko Uchida
Pages: 541-548 Published online on: 19 May 2014
Article
Model to predict the survival benefit of radiation for patients with rhabdomyosarcoma after surgery: A population-based study
Weidong Shen, Naoko Sakamoto, Limin Yang
Pages: 549-557 Published online on: 26 May 2014
Article
Daurinol, a catalytic inhibitor of topoisomerase IIα, suppresses SNU-840 ovarian cancer cell proliferation through cell cycle arrest in S phase
Kyungsu Kang, Chu Won Nho, Nam Doo Kim, Dae-Geun Song, Young Gyun Park, Minkyun Kim, Cheol-Ho Pan, Dongyun Shin, Seung Hyun Oh, Ho-Suk Oh
Pages: 558-566 Published online on: 16 May 2014
Article
Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer
Soichiro Honjo, Jaffer A. Ajani, Ailing W. Scott, Qiongrong Chen, Heath D. Skinner, John Stroehlein, Randy L. Johnson, Shumei Song
Pages: 567-574 Published online on: 21 May 2014
Article
Human colorectal CD24+ cancer stem cells are susceptible to epithelial-mesenchymal transition
Miho Okano, Masamitsu Konno, Yoshihiro Kano, Hirotoshi Kim, Koichi Kawamoto, Masahisa Ohkuma, Naotsugu Haraguchi, Takehiko Yokobori, Koshi Mimori, Hirofumi Yamamoto, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori, Hideshi Ishii
Pages: 575-580 Published online on: 23 May 2014
Article
Plastic induction of CD133AC133-positive cells in the microenvironment of glioblastoma spheroids
Ken Ohnishi, Toshiaki Tani, Shin-Ichi Bando, Nobuo Kubota, Yoshihiro Fujii, Osamu Hatano, Hirosi Harada
Pages: 581-586 Published online on: 03 June 2014
Article
Differential expression of miRNAs in colon cancer between African and Caucasian Americans: Implications for cancer racial health disparities
Ellen Li, Ping Ji, Nengtai Ouyang, Yuanhao Zhang, Xin Yu Wang, Deborah C. Rubin, Nicholas O. Davidson, Roberto Bergamaschi, Kenneth R. Shroyer, Stephanie Burke, Wei Zhu, Jennie L. Williams
Pages: 587-594 Published online on: 27 May 2014
Article
The estrogen receptor signaling pathway activated by phthalates is linked with transforming growth factor-β in the progression of LNCaP prostate cancer models
Hye-Rim Lee, Kyung-A Hwang, Kyung-Chul Choi
Pages: 595-602 Published online on: 22 May 2014
Article
Deep sequencing reveals complex mechanisms of microRNA deregulation in colorectal cancer
Gaofeng Liang, Junsheng Li, Bo Sun, Shuchun Li, Lanxin Lü, Yuanyuan Wang, Baoan Chen, Zhongdang Xiao
Pages: 603-610 Published online on: 29 May 2014
Article
Klotho suppresses growth and invasion of colon cancer cells through inhibition of IGF1R-mediated PI3K/AKT pathway
Xin-Xiang Li, Li-Yong Huang, Jun-Jie Peng, Lei Liang, De-Bing Shi, Hong-Tu Zheng, San-Jun Cai
Pages: 611-618 Published online on: 09 May 2014
Article
Integrated analysis of long non-coding RNAs and mRNA expression profiles reveals the potential role of lncRNAs in gastric cancer pathogenesis
Xiao-Cong Lin, Ying Zhu, Wen-Biao Chen, Lie-Wen Lin, De-Heng Chen, Jian-Rong Huang, Kai Pan, Yan Lin, Bi-Tao Wu, Yong Dai, Zhi-Guang Tu
Pages: 619-628 Published online on: 09 May 2014
Article
MST4 promotes hepatocellular carcinoma epithelial-mesenchymal transition and metastasis via activation of the p-ERK pathway
Zhen-Hai Lin, Liying Wang, Ju-Bo Zhang, Yanfeng Liu, Xiao-Qiang Li, Lei Guo, Bo Zhang, Wen-Wei Zhu, Qing-Hai Ye
Pages: 629-640 Published online on: 22 May 2014
Article
Upregulation of FGFR1 expression is associated with parathyroid carcinogenesis in HPT-JT syndrome due to an HRPT2 splicing mutation
Ji-Young Lee, Su Yeon Kim, Eun-Yeong Mo, Eun-Sook Kim, Je-Ho Han, Lee-So Maeng, An-Hee Lee, Jung Woo Eun, Suk Woo Nam, Sung-Dae Moon
Pages: 641-650 Published online on: 29 May 2014
Article
Gemcitabine inhibits the micrometastasis of non-small cell lung cancer by targeting the EpCAM-positive circulating tumor cells via the HGF/cMET pathway
Z. J. Liao, Y. H. Guo, Z. Zhao, J. T. Yao, R. Xu, K. J. Nan
Pages: 651-658 Published online on: 26 May 2014
Article
Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells
Lei Liang, Qian Li, Li Yong Huang, Da Wei Li, Yu Wei Wang, Xin Xiang Li, San Jun Cai
Pages: 659-666 Published online on: 21 May 2014
Article
Licochalcone A, a natural chalconoid isolated from Glycyrrhiza inflata root, induces apoptosis via Sp1 and Sp1 regulatory proteins in oral squamous cell carcinoma
Jung Jae Cho, Jung-Il Chae, Goo Yoon, Ka Hwi Kim, Jin Hyoung Cho, Seung-Sik Cho, Young Sik Cho, Jung-Hyun Shim
Pages: 667-674 Published online on: 23 May 2014
Article
Nutlin-3 induces BCL2A1 expression by activating ELK1 through the mitochondrial p53-ROS-ERK1/2 pathway
Sun-Young Lee, Hyun Chul Choi, Yun-Jeong Choe, Seok Joon Shin, Sug Hyung Lee, Ho-Shik Kim
Pages: 675-682 Published online on: 26 May 2014
Article
Tanshinone IIA induces cytochrome c-mediated caspase cascade apoptosis in A549 human lung cancer cells via the JNK pathway
Jian Zhang, Ju Wang, Jiu-Yang Jiang, Shang-Dian Liu, Kai Fu, Hong-Yu Liu
Pages: 683-690 Published online on: 28 May 2014
Article
The role of nuclear EpICD in extrahepatic cholangiocarcinoma: Association with β-catenin
Sarangerel Jachin, Jun Sang Bae, Jong Jin Sung, Ho Sung Park, Kyu Yun Jang, Myoung Ja Chung, Dae Gohn Kim, Woo Sung Moon
Pages: 691-698 Published online on: 28 May 2014
Article
β-elemene inhibits stemness, promotes differentiation and impairs chemoresistance to temozolomide in glioblastoma stem-like cells
Ting-Zhun Zhu, Xiao-Ming Li, Li-Han Luo, Zhen-Quan Song, Xu Gao, Zhi-Qing Li, Jing-Yuan Su, Guo-Biao Liang
Pages: 699-709 Published online on: 19 May 2014
Article
Podocalyxin-like 1 is associated with tumor aggressiveness and metastatic gene expression in human oral squamous cell carcinoma
Cheng-Wei Lin, Min-Siou Sun, Han-Chung Wu
Pages: 710-718 Published online on: 08 May 2014
Article
Upregulation of the putative oncogene COTE1 contributes to human hepatocarcinogenesis through modulation of WWOX signaling
Hai Zhang, Yuan Tian, Jian Shen, Yun Wang, Yonghua Xu, Yuping Wang, Zeguang Han, Xiangcheng Li
Pages: 719-731 Published online on: 03 June 2014
Article
Transcutaneous application of CO2 enhances the antitumor effect of radiation therapy in human malignant fibrous histiocytoma
Yasuo Onishi, Toshihiro Akisue, Teruya Kawamoto, Takeshi Ueha, Hitomi Hara, Mitsunori Toda, Risa Harada, Masaya Minoda, Masayuki Morishita, Ryohei Sasaki, Kotaro Nishida, Ryosuke Kuroda, Masahiro Kurosaka
Pages: 732-738 Published online on: 29 May 2014
Article
miR-451: Potential role as tumor suppressor of human hepatoma cell growth and invasion
Xuemin Liu, Xufeng Zhang, Junxi Xiang, Yi Lv, Jianhua Shi
Pages: 739-745 Published online on: 19 May 2014
Article
miRNA microarray reveals specific expression in the peripheral blood of glioblastoma patients
Lun Dong, Yuping Li, Chongxu Han, Xiaodong Wang, Lei She, Hengzhu Zhang
Pages: 746-756 Published online on: 22 May 2014
Article
The anticancer effect and mechanism of α-hederin on breast cancer cells
Lin Cheng, Tian-Song Xia, Yi-Fen Wang, Wenbin Zhou, Xiu-Qing Liang, Jin-Qiu Xue, Liang Shi, Ying Wang, Qiang Ding, Minhai Wang
Pages: 757-763 Published online on: 19 May 2014
Article
Helicobacter pylori cytotoxin-associated gene A protein upregulates α-enolase expression via Src/MEK/ERK pathway: Implication for progression of gastric cancer
Shuaiyin Chen, Guangcai Duan, Rongguang Zhang, Qingtang Fan
Pages: 764-770 Published online on: 19 May 2014
Article
A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway
Tian-En Wang, Yong-Kang Wang, Jing Jin, Bai-Ling Xu, Xiao-Guang Chen
Pages: 771-781 Published online on: 22 May 2014
Article
The novel pterostilbene derivative ANK-199 induces autophagic cell death through regulating PI3 kinase class III/beclin 1/Atg‑related proteins in cisplatin‑resistant CAR human oral cancer cells
Min-Tsang Hsieh, Hao-Ping Chen, Chi-Cheng Lu, Jo-Hua Chiang, Tian-Shung Wu, Daih-Huang Kuo, Li-Jiau Huang, Sheng-Chu Kuo, Jai-Sing Yang
Pages: 782-794 Published online on: 02 June 2014
Article
Oridonin inhibits the proliferation of human osteosarcoma cells by suppressing Wnt/β-catenin signaling
Yang Liu, Ying-Zi Liu, Ran-Xi Zhang, Xing Wang, Zi-Jun Meng, Jun Huang, Ke Wu, Jin-Yong Luo, Guo-Wei Zuo, Liang Chen, Liang-Jun Yin, Zhong-Liang Deng, Bai-Cheng He
Pages: 795-803 Published online on: 22 May 2014
Article
The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays antitumor activity in vivo
Gui'e Xie, Hongping Tang, Shaoqing Wu, Jingsong Chen, Jiangwen Liu, Can Liao
Pages: 804-812 Published online on: 26 May 2014
Article
Knockdown of toll-like receptor 4 inhibits human NSCLC cancer cell growth and inflammatory cytokine secretion in vitro and in vivo
Dan Li, Yingli Jin, Ying Sun, Jing Lei, Chaoying Liu
Pages: 813-821 Published online on: 02 June 2014
Article
Differentially expressed proteins in human breast cancer cells sensitive and resistant to paclitaxel
Nela Pavlikova, Irena Bartonova, Lucia Dincakova, Petr Halada, Jan Kovar
Pages: 822-830 Published online on: 03 June 2014
Article
Synthesis and anticancer activity of new flavonoid analogs and inconsistencies in assays related to proliferation and viability measurements
Alaina M. Forbes, Huimin Lin, Gary G. Meadows, G. Patrick Meier
Pages: 831-842 Published online on: 21 May 2014
Article
Involvement of histone H3 phosphorylation via the activation of p38 MAPK pathway and intracellular redox status in cytotoxicity of HL-60 cells induced by Vitex agnus-castus fruit extract
Hidetomo Kikuchi, Bo Yuan, Eisuke Yuhara, Masahiko Imai, Ryota Furutani, Shin Fukushima, Shingo Hazama, Chieko Hirobe, Kunio Ohyama, Norio Takagi, Hiroo Toyoda
Pages: 843-852 Published online on: 21 May 2014
Article
Mammalian sterile-like 1 kinase inhibits TGFβ and EGF‑dependent regulation of invasiveness, migration and proliferation of HEC-1-A endometrial cancer cells
Sanaz Attarha, Sonia Andersson, Miriam Mints, Serhiy Souchelnytskyi
Pages: 853-860 Published online on: 19 May 2014
Article
Exercise effects on polyp burden and immune markers in the ApcMin/+ mouse model of intestinal tumorigenesis
Jamie L. McClellan, Jennifer L. Steiner, Stani D. Day, Reilly T. Enos, Mark J. Davis, Udai P. Singh, E. Angela Murphy
Pages: 861-868 Published online on: 22 May 2014
Article
HOXB13 regulates the prostate-derived Ets factor: Implications for prostate cancer cell invasion
In-Je Kim, Taek Won Kang, Taeoh Jeong, Young-Rang Kim, Chaeyong Jung
Pages: 869-876 Published online on: 03 June 2014
Article
Cytochrome P450 3A-mediated metabolism of the topoisomerase I inhibitor 9-aminocamptothecin: Ιmpact on cancer therapy
Alexandra Maier-Salamon, Theresia Thalhammer, Gottfried Reznicek, Michaela Böhmdorfer, István Zupkó, Alexander Hartl, Walter Jaeger
Pages: 877-886 Published online on: 29 May 2014
Article
Modulation of uPA, MMPs and their inhibitors by a novel nutrient mixture in human glioblastoma cell lines
M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 887-894 Published online on: 26 May 2014
Article