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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2010 Volume 37 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Behind the scenes: Unravelling the molecular mechanisms of p53 target gene selectivity (Review)

Leonie Smeenk, Marion Lohrum
Pages: 1061-1070
Published online on: 01 November 2010

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Review

Augmentation of the ubiquitin-mediated proteolytic system by F-box and additional motif-containing proteins (Review)

Kazuyuki Sato, Kenichi Yoshida
Pages: 1071-1076
Published online on: 01 November 2010

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Article Open Access

Somatostatin analogue inhibits the mobility of prostate carcinoma cells: A new therapeutic method for advanced prostate carcinoma

Xiaoyan Tang, Susumu Takekoshi, Johbu Itoh, Shinobu Umemura, Sunao Shoji, Toshiro Terachi, Robert Yoshiyuki Osamura
Pages: 1077-1083
Published online on: 01 November 2010

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Article Open Access

Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis

Masahiko Ajiro, Toshihiko Nishidate, Toyomasa Katagiri, Yusuke Nakamura
Pages: 1085-1093
Published online on: 01 November 2010

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Article

Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells

Soichi Iwai, Atsuko Yonekawa, Chie Harada, Masakazu Hamada, Wataru Katagiri, Mituhiro Nakazawa, Yoshiaki Yura
Pages: 1095-1103
Published online on: 01 November 2010

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Article

Clinical significance of ASB9 in human colorectal cancer

Masayoshi Tokuoka, Norikatsu Miyoshi, Toshiki Hitora, Koshi Mimori, Fumiaki Tanaka, Koichi Shibata, Hideshi Ishii, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori
Pages: 1105-1111
Published online on: 01 November 2010

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Article

Prediction of the response to chemotherapy in advanced esophageal cancer by gene expression profiling of biopsy samples

Masaaki Motoori, Ichiro Takemasa, Makoto Yamasaki, Takamichi Komori, Atsushi Takeno, Hiroshi Miyata, Shuji Takiguchi, Yoshiyuki Fujiwara, Takushi Yasuda, Masahiko Yano, Nariaki Matsuura, Kenichi Matsubara, Morito Monden, Masaki Mori, Yuichiro Doki
Pages: 1113-1120
Published online on: 01 November 2010

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Article

Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity

Akihiro Inoue, Hisaaki Takahashi, Hironobu Harada, Shohei Kohno, Shiro Ohue, Kana Kobayashi, Hajime Yano, Junya Tanaka, Takanori Ohnishi
Pages: 1121-1131
Published online on: 01 November 2010

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Article

Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53

Shiho Ohnishi, Manabu Futamura, Hiroki Kamino, Yasuyuki Nakamura, Noriaki Kitamura, Yuji Miyamoto, Takafumi Miyamoto, Daisuke Shinogi, Olga Goda, Hirofumi Arakawa
Pages: 1133-1141
Published online on: 01 November 2010

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Article

Mechanisms behind COX-1 and COX-2 inhibition of tumor growth in vivo

Hans Axelsson, Christina Lönnroth, Marianne Andersson, Kent Lundholm
Pages: 1143-1152
Published online on: 01 November 2010

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Article

Abnormal expression of Endoglin and its receptor complex (TGF-β1 and TGF-β receptor II) as early angiogenic switch indicator in premalignant lesions of the colon mucosa

Graziella Bellone, Claudia Gramigni, Barbara Vizio, Francesco A. Mauri, Adriana Prati, Dino Solerio, Luca Dughera, Enrico Ruffini, Guido Gasparri, Michele Camandona
Pages: 1153-1165
Published online on: 01 November 2010

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Article

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts

Antonino B. D'Assoro, Alexey Leontovich, Angela Amato, Jennifer R. Ayers-Ringler, Cosima Quatraro, Kari Hafner, Robert B. Jenkins, Massimo Libra, James Ingle, Franca Stivala, Evanthia Galanis, Jeffrey L. Salisbury
Pages: 1167-1176
Published online on: 01 November 2010

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Article

Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway

Min Jung Kim, Tae Hwa Lee, Sung Han Kim, Yeon-Joo Choi, Jeonghoon Heo, Young-Ho Kim
Pages: 1177-1185
Published online on: 01 November 2010

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Article

Amifostine enhancement of the anti-cancer effects of paclitaxel in endometrial cancer is TP53-dependent

Wentao Luo, Fan Wu, Ruba Elmaoued, Brandon B. Beck, Edgar Fischer, Xiangbing Meng, Kimberly K. Leslie, Donghai Dai
Pages: 1187-1194
Published online on: 01 November 2010

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Article

Parity is associated with an expanded macrophage population in the mammary gland

Wei Zhao, Clinton J. Grubbs, Ronald K. Myers, Marit Nilsen-Hamilton
Pages: 1195-1202
Published online on: 01 November 2010

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Article

Optimization studies for the coupling of bispecific antibodies to viral anchor molecules of a tumor vaccine

Philippe Fournier, Maximilian Aigner, Volker Schirrmacher
Pages: 1203-1217
Published online on: 01 November 2010

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Article

Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer

Cristiana Lo Nigro, Martino Monteverde, Michela Riba, Laura Lattanzio, Federica Tonissi, Ornella Garrone, Abdelhamid Heouaine, Fabio Gallo, Marcello Ceppi, Felice Borghi, Alberto Comino, Marco Merlano
Pages: 1219-1228
Published online on: 01 November 2010

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Article

Anti-proliferative and anti-invasive properties of a purified fraction from Streptomyces sp. H7372

Wai Kien Yip, Sarot Cheenpracha, Leng Chee Chang, Coy Choke Ho, Heng Fong Seow
Pages: 1229-1241
Published online on: 01 November 2010

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Article

Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondria-dependent signal pathways

Jehn-Hwa Kuo, Yung-Lin Chu, Jai-Sing Yang, Jing-Pin Lin, Kuang-Chi Lai, Hsiu-Maan Kuo, Te-Chun Hsia, Jing-Gung Chung
Pages: 1243-1250
Published online on: 01 November 2010

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Article

Angiotensin II induces tumor progression and fibrosis in intrahepatic cholangiocarcinoma through an interaction with hepatic stellate cells

Koichi Okamoto, Hidehiro Tajima, Tetsuo Ohta, Shinichi Nakanuma, Hironori Hayashi, Hisatoshi Nakagawara, Ichiro Onishi, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Tani, Takashi Fujimura, Masato Kayahara, Shinichi Harada, Tomohiko Wakayama, Shoichi Iseki
Pages: 1251-1259
Published online on: 01 November 2010

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Article

Down-regulation of CacyBP is associated with poor prognosis and the effects on COX-2 expression in breast cancer

Fang Nie, Xiao-Ling Yu, Xiao-Ge Wang, Yu-Fu Tang, Ling-Ling Wang, Lie Ma
Pages: 1261-1269
Published online on: 01 November 2010

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Article Open Access

Comparative proteomic analysis of the ribosomes in 5-fluorouracil resistance of a human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis

Kosei Kimura, Akira Wada, Masami Ueta, Akihiko Ogata, Satoru Tanaka, Akiko Sakai, Hideji Yoshida, Hideo Fushitani, Akiko Miyamoto, Masakazu Fukushima, Toshio Uchiumi, Nobuhiko Tanigawa
Pages: 1271-1278
Published online on: 01 November 2010

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Article

Neuroblastoma cells can be classified according to glycosphingolipid expression profiles identified by liquid chromatography-tandem mass spectrometry

Tomonori Kaneko, Hajime Okita, Hideki Nakajima, Kazutoshi Iijima, Nao Ogasawara, Yoshitaka Miyagawa, Yohko U. Katagiri, Atsuko Nakagawa, Nobutaka Kiyokawa, Toshinori Sato, Junichiro Fujimoto
Pages: 1279-1288
Published online on: 01 November 2010

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Article

Calpain is involved in cisplatin-induced endothelial injury in an in vitro three-dimensional blood vessel model

Ryoji Eguchi, Yoshihiro Fujimori, Toshiro Ohta, Kazuhiro Kunimasa, Takashi Nakano
Pages: 1289-1296
Published online on: 01 November 2010

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Article

Pharmacological inhibition of Rho-kinase (ROCK) signaling enhances cisplatin resistance in neuroblastoma cells

Catharine A. Street, Alissa A. Routhier, Carrie Spencer, Ashley L. Perkins, Katherine Masterjohn, Alexander Hackathorn, John Montalvo, Emily A. Dennstedt, Brad A. Bryan
Pages: 1297-1305
Published online on: 01 November 2010

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Article

Parthenolide treatment activates stress signaling proteins in high-risk acute lymphoblastic leukemia cells with chromosomal translocation t(4;11)

Susan J. Zunino, David H. Storms, Jonathan M. Ducore
Pages: 1307-1313
Published online on: 01 November 2010

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Article

Suppression of p21 by c-Myc through members of miR-17 family at the post-transcriptional level

Zaozao Wang, Mei Liu, Hongxia Zhu, Wei Zhang, Shun He, Chenfei Hu, Lanping Quan, Jinfeng Bai, Ningzhi Xu
Pages: 1315-1321
Published online on: 01 November 2010

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Article

Suppression of RIZ in biologically unfavourable neuroblastomas

Janos Geli, Nimrod Kiss, Per Kogner, Catharina Larsson
Pages: 1323-1330
Published online on: 01 November 2010

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Article

Hedyotis Diffusa Willd extract induces apoptosis via activation of the mitochondrion-dependent pathway in human colon carcinoma cells

Jiumao Lin, Youqin Chen, Lihui Wei, Xuzhen Chen, Wei Xu, Zhenfeng Hong, Thomas J. Sferra, Jun Peng
Pages: 1331-1338
Published online on: 01 November 2010

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Article

Increased Cul1 expression promotes melanoma cell proliferation through regulating p27 expression

Guangdi Chen, Gang Li
Pages: 1339-1344
Published online on: 01 November 2010

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Article

Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: The role of reactive oxygen species and Akt

Xiao-Chun Zhao, Li Tian, Jian-Guo Cao, Fei Liu
Pages: 1345-1352
Published online on: 01 November 2010

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Journal Cover
July-2026 Volume 69 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Emerging agents that target signaling pathways in cancer fibroblast cells (Review)

Yan Wan, Xiang-Qing Liu, Dong Liu, Ke-Di Li, Dan-Dan Zhang
Article Number: 87
Published online on: 03 June 2026

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Review Open Access

Metabolic remodeling by circular RNAs in gastric tumorigenesis: From mechanisms to biomarker discovery (Review)

Xinyi Liang, Tianlin Wang, Jiale Ma, Shuangmei Zhao, Wang Gao, Yan Yang, Xinyuan Zhang, Huizhen Li
Article Number: 86
Published online on: 03 June 2026

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Correction Open Access

[Corrigendum] Cell density‑dependent regulation of p73 in breast cancer cells

Chaitali Tophkhane, Shihe Yang, Zhizhuang Joe Zhao, Xiaohe Yang
Article Number: 85
Published online on: 25 May 2026

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Review Open Access

P2X7 receptor: An emerging therapeutic target in acute myeloid leukemia (Review)

Yunqing Liu, Hongfan Xue, Hanheng Mai, Tan Sang, Zonghong Li, Na Wang, Lili Feng
Article Number: 84
Published online on: 22 May 2026

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Expression of Concern Open Access

[Expression of Concern] Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects

D. Carlisi, B. Vassallo, M. Lauricella, S.  Emanuele, A. D'anneo, E. Di Leonardo, P. Di Fazio, R.  Vento, G.  Tesoriere
Article Number: 83
Published online on: 20 May 2026

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Article Open Access

Integrin beta 4 promotes colorectal cancer progression by upregulating Ezrin and activating the Wnt/β‑catenin signaling pathway

Jing Wang, Yi Si, Mingda Xuan, Shuangshuang Han, Kunyi Liu, Jiao Jiao, Xiaoyan Men, Hongfei Li, Jia Wang, Ting Liu, Weifang Yu
Article Number: 82
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Semaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells

Pin-Hao Ko, Govinda Lenka, Yu-An Chen, Eric Y. Chuang, Mong-Hsun Tsai, Yuh-Pyng Sher, Liang-Chuan Lai
Article Number: 81
Published online on: 18 May 2026

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Review Open Access

snoRNAs and their derived sdRNAs: Emerging regulators, biomarkers, and therapeutic targets in human cancers (Review)

Jiahui Mao, Hao Lin, Feng Gu, Zhaoji Pan
Article Number: 80
Published online on: 15 May 2026

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Review Open Access

Deubiquitinating enzymes in cervical cancer: Molecular mechanisms and therapeutic implications (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 79
Published online on: 14 May 2026

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Article Open Access

BMP4 derived from human gastrointestinal carcinoma cells impairs myogenic differentiation: A possible in vitro mechanism of cancer‑induced cachexia

Kazuki Higure, Yoshihiko Kitajima, Naoya Kimura, Shota Ikeda, Shohei Matsufuji, Tomokazu Tanaka, Hirokazu Noshiro
Article Number: 78
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Radiation‑inducible silencing of uPA and uPAR in vitro and in vivo in meningioma

Venkateswara Rao Gogineni, Arun Kumar Nalla, Reshu Gupta, Bharathi Gorantla, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao
Article Number: 77
Published online on: 11 May 2026

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Review Open Access

Circulating proteins as biomarkers of response to cancer immunotherapy (Review)

Celeste Pinard, Angeline Ginzac, Catherine Abrial, Xavier Durando, Nina Radosevic‑Robin
Article Number: 76
Published online on: 06 May 2026

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Correction Open Access

[Corrigendum] Tumor necrosis factor‑α triggers opposing signals in head and neck squamous cell carcinoma and induces apoptosis via mitochondrial‑ and non‑mitochondrial‑dependent pathways

Denis Selimovic, Renate   U. Wahl, Emmanuelle Ruiz, Rizwan Aslam, Thomas   W. Flanagan, Sofie-Yasmin Hassan, Simeon Santourlidis, Youssef Haikel, Paul Friedlander, Mosaad Megahed, Emad Kandil, Mohamed Hassan
Article Number: 75
Published online on: 27 April 2026

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Journal Cover
August-2026 Volume 69 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Downregulation of uPA/uPAR inhibits intermittent hypoxia‑induced epithelial‑mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells

Reshu Gupta, Chandramu Chetty, Praveen Bhoopathi, Sajani Lakka, Sanjeeva Mohanam, Asti S. Rao, Dzung H. Dinh
Article Number: 89
Published online on: 08 June 2026

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Review Open Access

Targeted therapy in BRAF‑mutant melanoma: Advances and challenges (Review)

Lu Zhang, Dongliang Shen, Jianguo Feng, Liling Tang
Article Number: 88
Published online on: 04 June 2026

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