| Chemoenzymatic preparation of intermediates for the taxol side chain and analogs
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Authors: Bimal K. Banik, Mahima Negi, Maghar S. Manhas, Ajay K. Bose |
Affiliations: Department of Chemistry, The University of Texas Pan American, Edinburg, TX 78539, USA. banik@panam.edu
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Doi: 10.3892/mmr_00000258 |
Pages: 317-318 |
Abstract:
In the present study, optically active cis and trans α-hydroxy-β-lactams were prepared by Baker's yeast reduction of a racemic α-keto-β-lactam and by the hydrolysis of a racemic α-acetoxy β-lactam with the resting cells of Bacillus Subtilis.
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