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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2010 Volume 3 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Modulation of ryanodine receptor Ca2+ channels (Review)

Terutaka Ozawa
Pages: 199-204
Published online on: 01 March 2010

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Article

Genetic risk factors of chronic venous leg ulceration: Can molecular screening aid in the prevention of chronic venous insufficiency complications?

Tomasz Grzela, Agata Bialoszewska
Pages: 205-211
Published online on: 01 March 2010

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Article Open Access

Gene expression in the adrenal glands of three spontaneously hypertensive rat substrains

Mohammad S. Ashenagar, Masaki Tabuchi, Kosho Kinoshita, Kana Ooshima, Atsuko Niwa, Yuko Watanabe, Momoko Yoshida, Kazunori Shimada, Teruo Yasunaga, Hiromichi Yamanishi, Hideaki Higashino
Pages: 213-222
Published online on: 01 March 2010

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Article Open Access

Novel ETHE1 mutation in a carrier couple having prior offspring affected with ethylmalonic encephalopathy: Genetic analysis, clinical management and reproductive outcome

David J. Walsh, Eric S. Sills, Deborah M. Lambert, Nils Gregersen, Fergal D. Malone, Anthony P.H. Walsh
Pages: 223-226
Published online on: 01 March 2010

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Article

Anti-tumor activity of Sann-Joong-Kuey-Jian-Tang alone and in combination with 5-fluorouracil in a human colon cancer colo 205 cell xenograft model

Chun-Yuan Cheng, Yi-Hsiang Lin, Chin-Cheng Su
Pages: 227-231
Published online on: 01 March 2010

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Article

Expression of sphingosine-1 phosphate receptor in rat renal ischemia-reperfusion injury

Masahide Matsuyama, Kiyoaki Funao, Katsuyuki Kuratsukuri, Tomoaki Tanaka, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Norio Yoshimura, Rikio Yoshimura
Pages: 233-236
Published online on: 01 March 2010

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Article

Evaluation of valid reference genes during stimulation with static magnetic fields in human myoblast cultures

Jens Stern-Straeter, Gabriel A. Bonaterra, Stefanie Zügel, Stefan S. Kassner, Karl Hörmann, Ralf Kinscherf, Ulrich R. Goessler
Pages: 237-243
Published online on: 01 March 2010

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Article

Cysteinyl-leukotriene1 receptor is a potent target for the prevention and treatment of human urological cancer

Masahide Matsuyama, Rikio Yoshimura
Pages: 245-251
Published online on: 01 March 2010

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Article

Optimization of molecular detection of GD2 synthase mRNA in retinoblastoma

Viviana E. Laurent, Laura L. Otero, Valeria Vazquez, Sandra Camarero, Mariano R. Gabri, María Labraga, María T.G. De Dávila, Guillermo L. Chantada, Daniel F. Alonso
Pages: 253-259
Published online on: 01 March 2010

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Article

The intrinsic apoptotic signaling pathway in gastric adenocarcinomas of Brazilian patients: Immunoexpression of the Bcl-2 family (Bcl-2, Bcl-x, Bak, Bax, Bad) determined by tissue microarray analysis

Luis F.M. Barrezueta, Celina T.F. Oshima, Flávio O. Lima, Henrique De Oliveira Costa, Thiago S. Gomes, Ricardo A. Neto, Marcello F. De Franco
Pages: 261-267
Published online on: 01 March 2010

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Article

Tissue factor-factor VIIa regulates interleukin-8, tissue factor and caspase-7 expression in SW620 cells through protease-activated receptor-2 activation

Hong Zhou, Wenxia Shi, Baocheng Zhou, Donglin Guo, Ting Wang
Pages: 269-274
Published online on: 01 March 2010

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Article

Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma

Eunyoung Ha, Ji-Hye Bang, Jung N. Son, Ho-Chan Cho, Kyo-Chul Mun
Pages: 275-279
Published online on: 01 March 2010

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Article

Saponified sunflower and safflower oils inhibit melanogenesis in B16 melanoma cells

Jeung-Hyun Koo, Ikjae Lee, Seok-Kweon Yun, Han-Uk Kim, Byung-Hyun Park, Jin-Woo Park
Pages: 281-285
Published online on: 01 March 2010

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Article

Inhibitory effects of cytoplasmic-domain substituted epidermal growth factor receptor on growth, invasion and angiogenesis in human gastric cancer cells

Gang Liao, Ziwei Wang, Lin Zhao, Neng Zhang, Pujiang Dong
Pages: 287-294
Published online on: 01 March 2010

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Article

Lentiviral-mediated Smad4 RNAi promotes SMMC-7721 cell migration by regulation of MMP-2, VEGF and MAPK signaling

Xiaodan Huang, Shu Huang, Faming Zhang, Xiang Han, Lin Miao, Zheng Liu, Zhining Fan, Guozhong Ji
Pages: 295-299
Published online on: 01 March 2010

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Article

Different threshold levels for 2-amino-3,8 dimethylimidazo[4,5-f]quinoxaline (MelQx) initiation of lung and colon carcinogenesis and the effects of an additional initiation by 4 (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice

Satoshi Suzuki, Masanao Yokohira, Nozomi Hashimoto, Kousuke Saoo, Yoko Matsuda, Keiko Yamakawa, Yoko Nakano, Toshiya Kuno, Katsumi Imaida
Pages: 301-307
Published online on: 01 March 2010

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Article

Potentiation of the activity of cisplatin in a human colon tumour xenograft model by auristatin PYE, a structural modification of dolastatin 10

Ekatherine M. Prokopiou, Patricia A. Cooper, George R. Pettit, Michael C. Bibby, Steven D. Shnyder
Pages: 309-313
Published online on: 01 March 2010

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Article

Selective anticancer activity of β-lactams derived from polyaromatic compound

Bimal K. Banik, Frederick F. Becker
Pages: 315-316
Published online on: 01 March 2010

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Article

Chemoenzymatic preparation of intermediates for the taxol side chain and analogs

Bimal K. Banik, Mahima Negi, Maghar S. Manhas, Ajay K. Bose
Pages: 317-318
Published online on: 01 March 2010

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Article

Asymmetric synthesis of anticancer β-lactams via Staudinger reaction

Bimal K. Banik, Susanta Samajdar, Frederick F. Becker
Pages: 319-321
Published online on: 01 March 2010

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Article

Adiponectin suppresses inflammatory responses at the early phase of atherosclerosis in hyperglycemic rats

Jin-Bo Liu, Lin Jia, Bing-Rong Li, Li-Zhen Lan, Qian Ge, Hong-Ting Zhen, Hua-Cong Deng
Pages: 323-328
Published online on: 01 March 2010

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Article

Cysteinyl-leukotriene1 receptor antagonist prevents urological cancer cell growth through early apoptosis

Masahide Matsuyama, Kiyoaki Funao, Katsuyuki Kuratukuri, Tomoaki Tanaka, Yutaka Kawahito, Hajime Sano, Norio Yoshimura, Tatsuya Nakatani, Rikio Yoshimura
Pages: 329-332
Published online on: 01 March 2010

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Article

Combined effects of the proteasome inhibitor bortezomib and Hsp70 inhibitors on the B16F10 melanoma cell line

Azmi Yerlikaya, Emrah Okur, Semih Şeker, Nuray Erin
Pages: 333-339
Published online on: 01 March 2010

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Article

A novel putative interactor for the low density lipoprotein receptor cytoplasmic domain

Salvatore Costa, Aldo Nicosia, Maria A. Ragusa, Angelo B. Cefalù, Daniela Pollaccia, Davide Noto, Maurizio Averna, Fabrizio Gianguzza
Pages: 341-345
Published online on: 01 March 2010

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Article

Evaluation of insulin binding and signaling activity of newly synthesized chromium(III) complexes in vitro

Pawel Mackowiak, Zbigniew Krejpcio, Maciej Sassek, Przemyslaw Kaczmarek, Iwona Hertig, Joanna Chmielewska, Tatiana Wojciechowicz, Dawid Szczepankiewicz, Daria Wieczorek, Henryk Szymusiak, Krzysztof W. Nowak
Pages: 347-353
Published online on: 01 March 2010

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Article

CpG islands around exon 1 in the succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene are hypomethylated even in human and mouse hepatic tissues where SCOT gene expression is completely suppressed

Toshiyuki Fukao, Gaixiu Zhang, Naoki Matsuo, Naomi Kondo
Pages: 355-359
Published online on: 01 March 2010

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Article

Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823

Yong-Chang Chen, Feng Ren, Jian-Rong Sang, Yan Tao, Wen-Rong Xu
Pages: 361-366
Published online on: 01 March 2010

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Editorial Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Review Open Access

Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Review Open Access

Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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Retraction Open Access

[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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Article Open Access

FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Review Open Access

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Review Open Access

Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Review Open Access

Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Review Open Access

Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Review Open Access

Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Review Open Access

Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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Article Open Access

ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Review Open Access

Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Review Open Access

Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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Review Open Access

m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Review Open Access

Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Review Open Access

Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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Review Open Access

POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Review Open Access

Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Review Open Access

Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Review Open Access

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Review Open Access

Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Article Open Access

Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Article Open Access

Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Review Open Access

Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
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Published online on: 03 June 2026

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Article Open Access

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

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Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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