Pleural synovial sarcoma patient treated with combined chemotherapy and Endostar, plus sunitinib maintenance therapy: A case report and review of the literature

  • Authors:
    • Chong Teng
    • Li Li
    • Weixi Shen
    • Jingang Li
    • Ying Liu
    • Qiuying Jiang
    • Tao Xin
    • Dayong Huang
    • Xiaowei Song
    • Yanju Lv
    • Yinghua Jin
  • View Affiliations

  • Published online on: June 3, 2015     https://doi.org/10.3892/ol.2015.3311
  • Pages: 1141-1144
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Abstract

Synovial sarcoma is a rare, highly malignant soft-tissue tumor that occurs primarily in the extremities. At present, there is no effective clinical treatment for this condition. The present study reports the case of a 49‑year‑old male who was diagnosed with pleural synovial sarcoma and treated with recombinant human endostatin (Endostar) combined with chemotherapy for a total of six cycles, followed by sunitinib maintenance therapy. To the best of our knowledge, this is the first reported use of sunitinib for maintenance therapy in pleural synovial sarcoma. The patient survived for 25 months after the recurrence of the disease following surgery. The results indicate that this combination therapy was effective in the treatment of pleural synovial sarcoma. The present study also briefly reviews the literature on pleural synovial sarcoma, and the features and treatments for this rare case are discussed.
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August-2015
Volume 10 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Teng C, Li L, Shen W, Li J, Liu Y, Jiang Q, Xin T, Huang D, Song X, Lv Y, Lv Y, et al: Pleural synovial sarcoma patient treated with combined chemotherapy and Endostar, plus sunitinib maintenance therapy: A case report and review of the literature. Oncol Lett 10: 1141-1144, 2015
APA
Teng, C., Li, L., Shen, W., Li, J., Liu, Y., Jiang, Q. ... Jin, Y. (2015). Pleural synovial sarcoma patient treated with combined chemotherapy and Endostar, plus sunitinib maintenance therapy: A case report and review of the literature. Oncology Letters, 10, 1141-1144. https://doi.org/10.3892/ol.2015.3311
MLA
Teng, C., Li, L., Shen, W., Li, J., Liu, Y., Jiang, Q., Xin, T., Huang, D., Song, X., Lv, Y., Jin, Y."Pleural synovial sarcoma patient treated with combined chemotherapy and Endostar, plus sunitinib maintenance therapy: A case report and review of the literature". Oncology Letters 10.2 (2015): 1141-1144.
Chicago
Teng, C., Li, L., Shen, W., Li, J., Liu, Y., Jiang, Q., Xin, T., Huang, D., Song, X., Lv, Y., Jin, Y."Pleural synovial sarcoma patient treated with combined chemotherapy and Endostar, plus sunitinib maintenance therapy: A case report and review of the literature". Oncology Letters 10, no. 2 (2015): 1141-1144. https://doi.org/10.3892/ol.2015.3311