Open Access

Feasibility and safety of laparoscopic resection for gastric GISTs larger than 5 cm: Results from a prospective study

  • Authors:
    • Feng Cao
    • Ang Li
    • Jia Li
    • Yu Fang
    • Fei Li
  • View Affiliations

  • Published online on: July 30, 2015     https://doi.org/10.3892/ol.2015.3547
  • Pages: 2081-2086
  • Copyright: © Cao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The role of laparoscopic resection for large gastric gastrointestinal stromal tumors (GISTs), particularly those >5 cm, remains under debate due the possibility of intraoperative tumor rupture. To determine the feasibility and safety of the laparoscopic approach in the treatment of large gastric GISTs, a prospective study was performed between March 2011 and March 2014. Intraoperative tumor rupture was studied as the primary outcome. Secondary outcomes were the conversion rate, surgical duration, estimated blood loss, time to tolerate fluid and solid diets, length of post‑operative hospital stay and recurrence rate at the end of the follow‑up. A total of 16 patients were included in this study, with a tumor size of 7.04±1.53 cm (range, 5.2‑10.8 cm). No intraoperative tumor rupture occurred. The median duration of surgery was 88.1±31.9 min, with an estimated blood loss volume of 37.1±18.7 ml. No patient required a blood transfusion. The mean time until the start of oral intake for fluid and solid diets was 1.1±0.6 and 2.5±0.9 days, respectively. The median length of post‑operative hospital stay was 5.4±5.8 days. The follow‑up period for all patients was 16.9±11.2 months (range, 2‑38 months). No local or distant recurrence was observed. The study indicates that laparoscopic resection for large gastric GISTs is feasible and safe. Laparoscopic surgery should be considered as the standard approach in all cases, irrespective of tumor size or location.
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October-2015
Volume 10 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Cao F, Li A, Li J, Fang Y and Li F: Feasibility and safety of laparoscopic resection for gastric GISTs larger than 5 cm: Results from a prospective study. Oncol Lett 10: 2081-2086, 2015
APA
Cao, F., Li, A., Li, J., Fang, Y., & Li, F. (2015). Feasibility and safety of laparoscopic resection for gastric GISTs larger than 5 cm: Results from a prospective study. Oncology Letters, 10, 2081-2086. https://doi.org/10.3892/ol.2015.3547
MLA
Cao, F., Li, A., Li, J., Fang, Y., Li, F."Feasibility and safety of laparoscopic resection for gastric GISTs larger than 5 cm: Results from a prospective study". Oncology Letters 10.4 (2015): 2081-2086.
Chicago
Cao, F., Li, A., Li, J., Fang, Y., Li, F."Feasibility and safety of laparoscopic resection for gastric GISTs larger than 5 cm: Results from a prospective study". Oncology Letters 10, no. 4 (2015): 2081-2086. https://doi.org/10.3892/ol.2015.3547