Open Access

Sarcoidosis manifesting as hepatic and splenic nodules mimicking ovarian cancer metastases: A case report

  • Authors:
    • Yoshikuni Yonenaga
    • Fumiki Kushihata
    • Hitoshi Inoue
    • Jota Watanabe
    • Taiji Tohyama
    • Atsuro Sugita
    • Yasutsugu Takada
  • View Affiliations

  • Published online on: August 4, 2015     https://doi.org/10.3892/ol.2015.3566
  • Pages: 2166-2170
  • Copyright: © Yonenaga et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The current study presents a case of sarcoidosis manifesting as hepatic and splenic nodules, which was difficult to differentiate from ovarian cancer metastases. A 24‑year‑old female, who was previously diagnosed with right ovarian cancer and underwent surgery at the age of 21, was found to have two nodules in the spleen revealed by contrast‑enhanced computed tomography (CT). 18F‑fluorodeoxyglucose positron emission tomography/CT revealed two abnormal high uptake lesions in the spleen and one abnormal high uptake lesion in the liver. Under a diagnosis of hepatic and splenic metastases from right ovarian cancer, a laparoscopic splenectomy and partial hepatectomy were performed. Histopathological examination showed that a large number of non‑caseating epithelioid cell granulomas formed these nodules, which was compatible with sarcoidosis. This case indicates that it is difficult to distinguish sarcoidosis from metastatic disease even using the latest modalities, and that laparoscopic surgery is a minimally invasive and useful tool for forming a differential diagnosis.
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October-2015
Volume 10 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Yonenaga Y, Kushihata F, Inoue H, Watanabe J, Tohyama T, Sugita A and Takada Y: Sarcoidosis manifesting as hepatic and splenic nodules mimicking ovarian cancer metastases: A case report. Oncol Lett 10: 2166-2170, 2015
APA
Yonenaga, Y., Kushihata, F., Inoue, H., Watanabe, J., Tohyama, T., Sugita, A., & Takada, Y. (2015). Sarcoidosis manifesting as hepatic and splenic nodules mimicking ovarian cancer metastases: A case report. Oncology Letters, 10, 2166-2170. https://doi.org/10.3892/ol.2015.3566
MLA
Yonenaga, Y., Kushihata, F., Inoue, H., Watanabe, J., Tohyama, T., Sugita, A., Takada, Y."Sarcoidosis manifesting as hepatic and splenic nodules mimicking ovarian cancer metastases: A case report". Oncology Letters 10.4 (2015): 2166-2170.
Chicago
Yonenaga, Y., Kushihata, F., Inoue, H., Watanabe, J., Tohyama, T., Sugita, A., Takada, Y."Sarcoidosis manifesting as hepatic and splenic nodules mimicking ovarian cancer metastases: A case report". Oncology Letters 10, no. 4 (2015): 2166-2170. https://doi.org/10.3892/ol.2015.3566