Medulloblastoma with soft‑tissue and skeletal metastases in an adult: A case report

  • Authors:
    • Dianzhong Geng
    • Xiaohua Song
    • Jing Liu
    • Zeshun Yu
    • Fangling Ning
  • View Affiliations

  • Published online on: August 11, 2015     https://doi.org/10.3892/ol.2015.3595
  • Pages: 2295-2298
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Abstract

Medulloblastoma (MB) is a highly malignant primary brain tumor, which occurs in the cerebellum or posterior cranial fossa. MB is most commonly identified in children <10 years of age. The disease is rare in adults, affecting patients aged between 30 and 50 years of age, with an incidence of 0.5 cases per 1,000,000 individuals. Extraneural metastases are reported in 7-10% of cases, most commonly involving the bones and more rarely involving the lymph nodes, visceral organs and bone marrow. The current study presents the case of a 36‑year-old male who underwent a gross total resection followed by radiation therapy to the craniospinal axis for the treatment of MB. The patient subsequently developed widespread metastasis, which involved the soft tissue of the occipital bone. Subsequently, the patient was administered palliative radiotherapy and initially exhibited a good clinical response. However, the patient succumbed at 18 months post‑diagnosis due to dissemination of the disease. The literature on the extraneural metastasis of MB is also reviewed in the current study.
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October-2015
Volume 10 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Geng D, Song X, Liu J, Yu Z and Ning F: Medulloblastoma with soft‑tissue and skeletal metastases in an adult: A case report. Oncol Lett 10: 2295-2298, 2015
APA
Geng, D., Song, X., Liu, J., Yu, Z., & Ning, F. (2015). Medulloblastoma with soft‑tissue and skeletal metastases in an adult: A case report. Oncology Letters, 10, 2295-2298. https://doi.org/10.3892/ol.2015.3595
MLA
Geng, D., Song, X., Liu, J., Yu, Z., Ning, F."Medulloblastoma with soft‑tissue and skeletal metastases in an adult: A case report". Oncology Letters 10.4 (2015): 2295-2298.
Chicago
Geng, D., Song, X., Liu, J., Yu, Z., Ning, F."Medulloblastoma with soft‑tissue and skeletal metastases in an adult: A case report". Oncology Letters 10, no. 4 (2015): 2295-2298. https://doi.org/10.3892/ol.2015.3595