Irradiation combined with surgery for function preservation in the treatment of extramedullary plasmacytoma of the left labia majora during pregnancy: A case report

  • Authors:
    • Jinlan He
    • Yulong Zhang
    • Qin Shen
    • Yan Li
    • Zhe Liu
    • Xingchen Peng
    • Yali Shen
    • Rui Yin
    • Nianyong Chen
  • View Affiliations

  • Published online on: August 27, 2015     https://doi.org/10.3892/ol.2015.3648
  • Pages: 3238-3242
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Abstract

Extramedullary plasmacytoma (EMP) in the vulva is extremely rare. The current study presents, for the first time, a case of EMP in the left labia majora in a 36‑year‑old patient during pregnancy. A painful 7x4x2‑cm mass with ulceration, pus and blood scabs, previously misdiagnosed as vulvar ulcer in a local hosipital, was proven to be an EMP by biopsy. Upon magnetic resonance imaging, the tumor was shown to occur in the left labia majora without lymphadenopathy. A complete multiple myeloma (MM) workup excluded coexistence with MM. The goal of treatment was to eradicate the tumor while synchronously preserving the vulva. Therefore, following the termination of the pregnancy, radiotherapy with a total dose of 4,500 cGy markedly reduced the size of the tumor. An extended local excision of the residual tumor, and anaplasty of the vulva preserved the appearance and function of the vulva to the utmost. No post‑operative radiation was administered, as the resection margins were not microscopically involved. There was no relapse, metastasis or progression to MM in a 9‑month post-operative follow-up period, but close follow-up and long-term surveillance are required.
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November-2015
Volume 10 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
He J, Zhang Y, Shen Q, Li Y, Liu Z, Peng X, Shen Y, Yin R and Chen N: Irradiation combined with surgery for function preservation in the treatment of extramedullary plasmacytoma of the left labia majora during pregnancy: A case report. Oncol Lett 10: 3238-3242, 2015
APA
He, J., Zhang, Y., Shen, Q., Li, Y., Liu, Z., Peng, X. ... Chen, N. (2015). Irradiation combined with surgery for function preservation in the treatment of extramedullary plasmacytoma of the left labia majora during pregnancy: A case report. Oncology Letters, 10, 3238-3242. https://doi.org/10.3892/ol.2015.3648
MLA
He, J., Zhang, Y., Shen, Q., Li, Y., Liu, Z., Peng, X., Shen, Y., Yin, R., Chen, N."Irradiation combined with surgery for function preservation in the treatment of extramedullary plasmacytoma of the left labia majora during pregnancy: A case report". Oncology Letters 10.5 (2015): 3238-3242.
Chicago
He, J., Zhang, Y., Shen, Q., Li, Y., Liu, Z., Peng, X., Shen, Y., Yin, R., Chen, N."Irradiation combined with surgery for function preservation in the treatment of extramedullary plasmacytoma of the left labia majora during pregnancy: A case report". Oncology Letters 10, no. 5 (2015): 3238-3242. https://doi.org/10.3892/ol.2015.3648