Open Access

Intramuscular dendritic fibromyxolipoma in a 24-year-old male: A case report and review of the literature

  • Authors:
    • Xia Xu
    • Wen Xiong
    • Liduan Zheng
    • Jie Yu
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  • Published online on: December 12, 2014     https://doi.org/10.3892/ol.2014.2794
  • Pages: 583-586
  • Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Dendritic fibromyxolipoma (DFML) is an uncommon, benign soft tumor that usually arises in the subcutis. To date, ~24 cases of DFML have been reported in the literature and only one of these has been in the muscle. The present study reports the case of a 24‑year‑old male with a slow‑growing, painless mass located deep in the triceps brachii in the left shoulder region. The mass was 14.0x8.5x8.0 cm in size, with well‑circumscribed margins. Microscopically, the resected mass was characterized by a proliferation of small spindle or stellate cells, prominent abundant myxoid stroma with ropey collagen bundles and admixed mature adipose tissue. Further immunohistochemical staining indicated that the spindle and stellate cells were reactive with cluster of differentiation 34, vimentin and B‑cell lymphoma‑2, but not with smooth muscle actin and desmin. Fluorescence in situ hybridization showed that the tumor cells did not have the DDIT3 alteration or amplification of MDM2. The tumor was confirmed to be a DFML due to the typical histological, immunophenotypic and genetic findings. To date, subsequent to 4 years of clinical follow‑up, there is no sign of recurrence or metastasis. The present study reports a case of DFML in the youngest known patient, and is the second reported case of an intramuscular DFML occurring in the triceps brachii in the left shoulder region. The study discusses the clinicopathological features and the differential diagnosis of DFML, with a review of the literature.
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February-2015
Volume 9 Issue 2

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Copy and paste a formatted citation
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Spandidos Publications style
Xu X, Xiong W, Zheng L and Yu J: Intramuscular dendritic fibromyxolipoma in a 24-year-old male: A case report and review of the literature. Oncol Lett 9: 583-586, 2015
APA
Xu, X., Xiong, W., Zheng, L., & Yu, J. (2015). Intramuscular dendritic fibromyxolipoma in a 24-year-old male: A case report and review of the literature. Oncology Letters, 9, 583-586. https://doi.org/10.3892/ol.2014.2794
MLA
Xu, X., Xiong, W., Zheng, L., Yu, J."Intramuscular dendritic fibromyxolipoma in a 24-year-old male: A case report and review of the literature". Oncology Letters 9.2 (2015): 583-586.
Chicago
Xu, X., Xiong, W., Zheng, L., Yu, J."Intramuscular dendritic fibromyxolipoma in a 24-year-old male: A case report and review of the literature". Oncology Letters 9, no. 2 (2015): 583-586. https://doi.org/10.3892/ol.2014.2794