Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review

  • Authors:
    • Shinichi Hayashi
    • Yoshiro Abe
    • Shigeki Tomita
    • Yuko Nakanishi
    • Shigeharu Miwa
    • Takahiko Nakajima
    • Kazuhiro Nomoto
    • Koichi Tsuneyama
    • Takahiro Fujimori
    • Johji Imura
  • View Affiliations

  • Published online on: February 26, 2015     https://doi.org/10.3892/ol.2015.2985
  • Pages: 2109-2111
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Abstract

Pure non‑gestational choriocarcinoma is a primary germ cell neoplasm that has been defined as a tumor without other germ cell elements. The current study presents an extremely rare case of non‑gestational pure choriocarcinoma in a postmenarcheal young female and describes details of the tumor, including the clinicopathological findings. The patient was a 10‑year‑old female who underwent salpingo‑oophorectomy. Histologically, the extensive hemorrhagic tumor was composed of choriocarcinoma without additional germ cell tumor components. The tumor cells were immunohistochemically positive for epithelial markers, including cytokeratins and epithelial membrane antigens, and there was a positive cytoplasmic reaction for β‑human chorionic gonadotropin in the syncytiotrophoblasts. Furthermore, numerous tumor cells were immunohistochemically positive for the β2‑microglobulin antibody. The patient received adjuvant cisplatin, etoposide and bleomycin chemotherapy, and is currently disease‑free without evidence of recurrence or metastasis subsequent to 62 months of follow‑up.
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May-2015
Volume 9 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Hayashi S, Abe Y, Tomita S, Nakanishi Y, Miwa S, Nakajima T, Nomoto K, Tsuneyama K, Fujimori T, Imura J, Imura J, et al: Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review. Oncol Lett 9: 2109-2111, 2015
APA
Hayashi, S., Abe, Y., Tomita, S., Nakanishi, Y., Miwa, S., Nakajima, T. ... Imura, J. (2015). Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review. Oncology Letters, 9, 2109-2111. https://doi.org/10.3892/ol.2015.2985
MLA
Hayashi, S., Abe, Y., Tomita, S., Nakanishi, Y., Miwa, S., Nakajima, T., Nomoto, K., Tsuneyama, K., Fujimori, T., Imura, J."Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review". Oncology Letters 9.5 (2015): 2109-2111.
Chicago
Hayashi, S., Abe, Y., Tomita, S., Nakanishi, Y., Miwa, S., Nakajima, T., Nomoto, K., Tsuneyama, K., Fujimori, T., Imura, J."Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review". Oncology Letters 9, no. 5 (2015): 2109-2111. https://doi.org/10.3892/ol.2015.2985