Primary mediastinal giant liposarcoma with smooth muscle and neural differentiation: A case report

  • Authors:
    • Jian Ma
    • Hong‑Mei Zhang
    • Li‑Wang Zhang
    • Min‑Wen Zheng
    • Min Yu
  • View Affiliations

  • Published online on: April 8, 2015     https://doi.org/10.3892/ol.2015.3103
  • Pages: 2667-2669
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Abstract

Liposarcoma has previously been described in Western studies, however, such cases are rarely reported in the mediastinum. In addition, the presence of a liposarcoma with smooth muscle and neural differentiation has not been previously reported. Thus, the present study describes the rare case of a 28‑year‑old Chinese male admitted to our hospital with the symptoms of chest tightness and shortness of breath due to a recurrent fibrolipoma in the mediastinum. The resected tumor measured 23 cm at its largest diameter, with histopathological and immunohistochemical features indicating a well‑differentiated liposarcoma accompanied by smooth muscle and neural differentiation. Following the resection, the patient underwent radiation treatment and remains alive with no evidence of disease recurrence at two months post‑surgery. To the best of our knowledge, the present study is the first to report a case of liposarcoma with smooth muscle and neural differentiation, which indicates that liposarcomas could potentially originate from stem cells. The present study highlights the fact that pathologists must carefully investigate the histopathological characteristics of liposarcomas in order to obtain an accurate diagnosis.
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June-2015
Volume 9 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Ma J, Zhang HM, Zhang LW, Zheng MW and Yu M: Primary mediastinal giant liposarcoma with smooth muscle and neural differentiation: A case report. Oncol Lett 9: 2667-2669, 2015
APA
Ma, J., Zhang, H., Zhang, L., Zheng, M., & Yu, M. (2015). Primary mediastinal giant liposarcoma with smooth muscle and neural differentiation: A case report. Oncology Letters, 9, 2667-2669. https://doi.org/10.3892/ol.2015.3103
MLA
Ma, J., Zhang, H., Zhang, L., Zheng, M., Yu, M."Primary mediastinal giant liposarcoma with smooth muscle and neural differentiation: A case report". Oncology Letters 9.6 (2015): 2667-2669.
Chicago
Ma, J., Zhang, H., Zhang, L., Zheng, M., Yu, M."Primary mediastinal giant liposarcoma with smooth muscle and neural differentiation: A case report". Oncology Letters 9, no. 6 (2015): 2667-2669. https://doi.org/10.3892/ol.2015.3103