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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2006 Volume 16 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Expression of vascular endothelial growth factor receptors is closely related to the histological grade of hepatocellular carcinoma

Nozomi Amaoka, Masanao Saio, Kenichi Nonaka, Hisashi Imai, Hiroyuki Tomita, Fumio Sakashita, Takao Takahashi, Yasuyuki Sugiyama, Tsuyoshi Takami, Yosuke Adachi
Pages: 3-10
Published online on: 01 July 2006

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Article

Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients

Shogo Sasao, Toru Hiyama, Shinji Tanaka, Masaharu Yoshihara, Wataru Yasui, Kazuaki Chayama
Pages: 11-15
Published online on: 01 July 2006

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Article

Does the degree of intratumoural microvessel density and VEGF expression have prognostic significance in osteosarcoma?

Eugene T.H. Ek, Joseline Ojaimi, Yasuyuki Kitagawa, Peter F.M. Choong
Pages: 17-23
Published online on: 01 July 2006

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Article

Effect of hepatocyte growth factor on endogenous hepatocarcinogenesis in rats fed a choline-deficient L-amino acid-defined diet

Chihiro Nakanishi, Akihiro Moriuchi, Akio Ido, Masatsugu Numata, Il-Deok Kim, Kazunori Kusumoto, Satoru Hasuike, Hiroo Abe, Kenji Nagata, Yutaka Akiyama, Hirofumi Uto, Hiroaki Kataoka, Hirohito Tsubouchi
Pages: 25-31
Published online on: 01 July 2006

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Article

Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas

Ji Tae Kim, Jong-Soo Kim, Kwang Won Ko, Doo-Sik Kong, Chang-Mo Kang, Mi Hyun Kim, Myung Jin Son, Hyun Seok Song, Hyung-Jin Shin, Dong-Sup Lee, Whan Eoh, Do-Hyun Nam
Pages: 33-39
Published online on: 01 July 2006

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Article

Loss of protein expression of hMLH1 and hMSH2 with double primary carcinomas of the stomach and colorectum

Manabu Yamamoto, Kenichi Taguchi, Hideo Baba, Kazuya Endo, Shunji Kohnoe, Takeshi Okamura, Yoshihiko Maehara
Pages: 41-47
Published online on: 01 July 2006

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Article

The role of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in microcystic meningiomas

Sun Ha Paek, Dong Gyu Kim, Chul-Kee Park, Ji Hoon Phi, Young Yim Kim, Soo Young Im, Jeong Eun Kim, Sung-Hye Park, Hee-Won Jung
Pages: 49-56
Published online on: 01 July 2006

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Article

Predictive and prognostic role of activated mammalian target of rapamycin in cervical cancer treated with cisplatin-based neoadjuvant chemotherapy

Leri S. Faried, Ahmad Faried, Tatsuya Kanuma, Takaaki Sano, Tomoko Nakazato, Tomohiro Tamura, Hiroyuki Kuwano, Takashi Minegishi
Pages: 57-63
Published online on: 01 July 2006

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Article

The TP53 codon 72 polymorphism and predisposition to adrenocortical cancer in Polish patients

Magdalena Ignaszak-Szczepaniak, Wanda Horst-Sikorska, Joanna Sawicka, Marta Kaczmarek, Ryszard Slomski
Pages: 65-71
Published online on: 01 July 2006

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Article

Development of a self-proliferating Leydig cell line: a hyper-sensitive E-screening model

James W. DuMond, Kamaleshwar P. Singh, Deodutta Roy
Pages: 73-77
Published online on: 01 July 2006

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Article

Activation of the PKB/Akt pathway in histological benign prostatic tissue adjacent to the primary malignant lesions

Axel S. Merseburger, Jörg Hennenlotter, Perikles Simon, Carolin C. Müller, Ursula Kühs, Ruth Knüchel-Clarke, Judd W. Moul, Arnulf Stenzl, Markus A. Kuczyk
Pages: 79-83
Published online on: 01 July 2006

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Article

Alterations in the Smad4 gene in hamster pancreatic duct adenocarcinomas and established cell lines

Kyoko Shimizu, Tsukasa Kitahashi, Hiromasa Fujii, Masahiro Tsutsumi, Toshio Mori, Kanya Honoki, Toshifumi Tsujiuchi
Pages: 85-89
Published online on: 01 July 2006

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Article

Enhancement of GLI1-transcriptional activity by β-catenin in human cancer cells

Osamu Maeda, Masashi Kondo, Takayoshi Fujita, Noriyasu Usami, Takayuki Fukui, Kaoru Shimokata, Takafumi Ando, Hidemi Goto, Yoshitaka Sekido
Pages: 91-96
Published online on: 01 July 2006

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Article

Acquired resistance to imatinib and secondary KIT exon 13 mutation in gastrointestinal stromal tumour

François Bertucci, Anthony Goncalves, Geneviève Monges, Anne Madroszyk, Jérome Guiramand, Vincent Moutardier, Tetsuro Noguchi, Patrice Dubreuil, Hagay Sobol
Pages: 97-101
Published online on: 01 July 2006

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Article

Immunohistochemical study of chymase-positive mast cells in inflammatory bowel disease

Akira Andoh, Yasuyuki Deguchi, Osamu Inatomi, Yuki Yagi, Shigeki Bamba, Tomoyuki Tsujikawa, Yoshihide Fujiyama
Pages: 103-107
Published online on: 01 July 2006

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Article

Chemokine receptor CCR7 enhances intrahepatic and lymphatic dissemination of human hepatocellular cancer

Carl C. Schimanski, Rüdiger Bahre, Ines Gockel, Theodor Junginger, Nektaria Simiantonaki, Stefan Biesterfeld, Tobias Achenbach, Thomas Wehler, Peter R. Galle, Markus Moehler
Pages: 109-113
Published online on: 01 July 2006

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Article

Extraskeletal myxoid chondrosarcoma arising from the clavicle

Shigeto Nakazora, Katsuyuki Kusuzaki, Takao Matsubara, Ken Shintani, Akihiko Matsumine, Kazuo Fukutome, Atsumasa Uchida
Pages: 115-118
Published online on: 01 July 2006

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Article

Erlotinib prevents pulmonary metastasis in curatively resected breast carcinoma using a mouse model

Young-Jin Choi, Seok-Jin Nam, Myung Jin Son, Dae-Kyeum Kim, Jeong-Han Kim, Jung-Hyun Yang, Mi-Hyun Kim, Hyun Seok Song, Do-Hyun Nam, Sa Ik Bang
Pages: 119-122
Published online on: 01 July 2006

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Article

Childhood thyroid carcinoma with BRAFT1799A mutation shows unique pathological features of poor differentiation

Atsushi Kumagai, Hiroyuki Namba, Norisato Mitsutake, Vladimir A. Saenko, Akira Ohtsuru, Masahiro Ito, Jaeduk Yoshimura Noh, Kiminori Sugino, Koichi Ito, Shunichi Yamashita
Pages: 123-126
Published online on: 01 July 2006

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Article

Role of p16 and p14ARF in radio- and chemosensitivity of malignant gliomas

Matthias Simon, David Voss, Tjoung-Won Park-Simon, Ralph Mahlberg, Gertraud Köster
Pages: 127-132
Published online on: 01 July 2006

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Article

A novel metronomic chemotherapy regimen of weekly platinum and daily oral etoposide in high-risk non-small cell lung cancer patients

P. Correale, D. Cerretani, C. Remondo, I. Martellucci, S. Marsili, M. La Placa, A. Sciandivasci, L. Paolelli, A. Pascucci, M. Rossi, M. Di Bisceglie, G. Giorgi, G. Gotti, G. Francini
Pages: 133-140
Published online on: 01 July 2006

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Article

Different mechanisms for anti-tumor effects of low- and high-dose cyclophosphamide

Yasuhide Motoyoshi, Kazuhisa Kaminoda, Ohki Saitoh, Keisuke Hamasaki, Kazuhiko Nakao, Nobuko Ishii, Yuji Nagayama, Katsumi Eguchi
Pages: 141-146
Published online on: 01 July 2006

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Article

A new strategy using autologous dendritic cells and lymphokine-activated killer cells for cancer immunotherapy: efficient maturation of DCs by co-culture with LAK cells in vitro

Yutaro Yano, Yuji Ueda, Tsuyohi Itoh, Nobuaki Fuji, Kaori Okugawa, Kei Naito, Kenichiro Imura, Junji Kohara, Takashi Hayashi, Kazuki Nakane, Yuko Matsuura, Keiichi Kawai, Hisakazu Yamagishi
Pages: 147-152
Published online on: 01 July 2006

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Article

PEA3 cooperates with c-Jun in regulation of HER2/neu transcription

Koshi Matsui, Kazuhito Sugimori, Hiraku Motomura, Naoko Ejiri, Kazuhiro Tsukada, Isao Kitajima
Pages: 153-158
Published online on: 01 July 2006

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Article

Cellular processing in the SW1222 cell line of mAb A33 directly and indirectly radiohalogenated

Johanna Höglund, Anna Orlova, Anders Sundin, Hans Lundqvist, Vladimir Tolmachev
Pages: 159-163
Published online on: 01 July 2006

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Article

Adoptive immunotherapy using autologous lymphocytes sensitized with HLA class I-matched allogeneic tumor cells

Yoshiyuki Yamaguchi, Akiko Ohshita, Katsuji Hironaka, Riki Okita, Makoto Okawaki, Kazuo Matsuura, Ichiro Nagamine, Takuhiro Ikeda, Masahiro Ohara, Jun Hihara
Pages: 165-169
Published online on: 01 July 2006

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Article

Suppression of U937 human monocytic leukemia cell growth by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., via induction of Cdk inhibitor p16 and down-regulation of pRB phosphorylation

Cheol Park, Gi Young Kim, Gun Do Kim, Won Ho Lee, Jae Hun Cheong, Nam Deuk Kim, Song-Ja Bae, Jee H Jung, Yung Hyun Choi
Pages: 171-176
Published online on: 01 July 2006

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Article

The relationship between survival and the expression of dihydropyrimidine dehydrogenase in patients with colorectal cancer

Tsukasa Hotta, Katsunari Takifuji, Katsutoshi Taniguchi, Masaki Sahara, Shozo Yokoyama, Kenji Matsuda, Takashi Higashiguchi, Toshiji Tominaga, Yoshimasa Oku, Hiroki Yamaue
Pages: 177-182
Published online on: 01 July 2006

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Article

Detection and expression of human papillomavirus oncogenes in non-small cell lung cancer

Marco Ciotti, Laura Giuliani, Vincenzo Ambrogi, Corrado Ronci, Arrigo Benedetto, Tommaso C. Mineo, Kari Syrjänen, Cartesio Favalli
Pages: 183-189
Published online on: 01 July 2006

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Article

A single-center report on clinical features and treatment response in patients with intestinal T cell non-Hodgkin's lymphomas

Barbara Jezersek Novakonic, Srdjan Novakonic, Snezana Frkovic-Grazio
Pages: 191-195
Published online on: 01 July 2006

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Article

Malignant tumors in two ancient populations: An approach to historical tumor epidemiology

Andreas G. Nerlich, Helmut Rohrbach, Beatrice Bachmeier, Albert Zink
Pages: 197-202
Published online on: 01 July 2006

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Article

DNA analysis as a tool for breast cancer malpractice determination: An interdisciplinary approach

Ersi Abaci Kalfoglou, Rehat Faikoglu, Sebnem Özcan, Gabriel Petridis, Hülya Yükseloglu, Sevil Atasoy
Pages: 203-206
Published online on: 01 July 2006

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Article

Expression of breast cancer specific gene-1 (BCSG-1/γ-synuclein) is associated with tumour grade but not with clinical outcome of patients with breast cancer

Tracey A. Martin, Kelvin Gomez, Gareth Watkins, Anthony Douglas-Jones, Robert E. Mansel, Wen G. Jiang
Pages: 207-212
Published online on: 01 July 2006

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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