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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2006 Volume 16 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Cystatins in non-small cell lung cancer: Tissue levels, localization and relation to prognosis

Bernd Werle, Ulrike Schanzenbächer, Tamara Turensek Lah, Eileen Ebert, Britta Jülke, Werner Ebert, Werner Fiehn, Klaus Kayser, Eberhard Spiess, Magnus Abrahamson, Janko Kos
Pages: 647-655
Published online on: 01 October 2006

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Article

Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer

Wilko I. Staiger, Johannes F. Coy, Rainer Grobholz, Ralf-Dieter Hofheinz, Nadine Lukan, Stefan Post, Matthias H. Schwarzbach, Frank Willeke
Pages: 657-661
Published online on: 01 October 2006

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Article

Differential expression in histologically normal crypts of ulcerative colitis suggests primary crypt disorder

Mijung Kim, Seungkoo Lee, Suk-Kyun Yang, Kyuyoung Song, Inchul Lee
Pages: 663-670
Published online on: 01 October 2006

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Article

The role of S100A1 in external auditory canal cholesteatoma

Ramin Naim, Karl Hormann
Pages: 671-675
Published online on: 01 October 2006

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Article

Assessment of the severity of liver disease and fibrotic change: The usefulness of hepatic CT perfusion imaging

Kazuhiko Hashimoto, Takamichi Murakami, Keizo Dono, Masatoshi Hori, Tonsok Kim, Masayuki Kudo, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Hiroaki Nagano, Koji Umeshita, Hironobu Nakamura, Morito Monden
Pages: 677-683
Published online on: 01 October 2006

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Article

Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis

Hideyuki Shima, Toru Hiyama, Shinji Tanaka, Masaharu Yoshihara, Koji Arihiro, Kazuaki Chayama
Pages: 685-691
Published online on: 01 October 2006

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Article

Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma

Baocun Sun, Shiwu Zhang, Danfang Zhang, Jing Du, Hua Guo, Xiulan Zhao, Wei Zhang, Xishan Hao
Pages: 693-698
Published online on: 01 October 2006

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Article

The S1P receptor modulator FTY720 prevents the development of experimental colitis in mice

Yasuyuki Deguchi, Akira Andoh, Yuki Yagi, Shigeki Bamba, Osamu Inatomi, Tomoyuki Tsujikawa, Yoshihide Fujiyama
Pages: 699-703
Published online on: 01 October 2006

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Article

Proteomic analysis of a highly metastatic gastric cancer cell line using two-dimensional differential gel electrophoresis

Masako Takikawa, Yasuto Akiyama, Kouji Maruyama, Ayako Suzuki, Feng Liu, Sachiko Tai, Chie Ohshita, Yoshihiro Kawaguchi, Etsurou Bandou, Yutaka Yonemura, Ken Yamaguchi
Pages: 705-711
Published online on: 01 October 2006

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Article

Inhibition of murine K-BALB and CT26 tumour growth using a Semliki Forest virus vector with enhanced expression of IL-18

C. P. Chikkanna-Gowda, S. McNally, B. J. Sheahan, M. N. Fleeton, G. J. Atkins
Pages: 713-719
Published online on: 01 October 2006

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Article

Expression of chemoresistance-related proteins in α-fetoprotein-producing adenocarcinoma of the digestive organs

Shingo Kamoshida, Mai Suzuki, Yoichi Sakurai, Masahiro Ochiai, Fumikazu Kimura, Sadahito Kuwao, Kazuki Sakamoto, Yoshikazu Sugimoto, Masakazu Fukushima, Yutaka Tsutsumi
Pages: 721-727
Published online on: 01 October 2006

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Article

Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer

Wen-Ling Kuo, Li-Yu Lee, Chi-Ming Wu, Chee-Chan Wang, Jau-Song Yu, Ying Liang, Chih-Hong Lo, Kuo-Hao Huang, Tsann-Long Hwang
Pages: 729-734
Published online on: 01 October 2006

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Article

Characteristic features of disseminated carcinomatosis of the bone marrow due to gastric cancer: The pathogenesis of bone destruction

Hiroki Kusumoto, Masaru Haraguchi, Yoko Nozuka, Yoshinao Oda, Masazumi Tsuneyoshi, Haruo Iguchi
Pages: 735-740
Published online on: 01 October 2006

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Article

Comparison of CD44 expression in primary tumours and metastases of colorectal cancer

R. Bendardaf, A. Algars, A. Elzagheid, E. Korkeila, R. Ristamäki, H. Lamlum, Y. Collan, K. Syrjänen, S. Pyrhönen
Pages: 741-746
Published online on: 01 October 2006

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Article

Differential expression in normal-adenoma-carcinoma sequence suggests complex molecular carcinogenesis in colon

Seungkoo Lee, Seunghyun Bang, Kyuyoung Song, Inchul Lee
Pages: 747-754
Published online on: 01 October 2006

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Article

AKAPs competing peptide HT31 disrupts the inhibitory effect of PKA on RhoA activity

Ying Wang, Yongchang Chen, Min Chen, Wenrong Xu
Pages: 755-761
Published online on: 01 October 2006

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Article

99mTc-tetrofosmin SPECT in solitary pulmonary nodule evaluation

Angela Spanu, Orazio Schillaci, Pietro Pirina, Antonio Arru, Giordano Madeddu, Francesca Chessa, Pietro Marongiu, Maria Elisabetta Solinas, Giuseppe Madeddu
Pages: 763-769
Published online on: 01 October 2006

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Article

Cyclooxygenase-2 inhibitor, nimesulide, improves radiation treatment against non-small cell lung cancer both in vitro and in vivo

Kristopher R. Grimes, Graham W. Warren, Fang Fang, Yong Xu, William H. St. Clair
Pages: 771-776
Published online on: 01 October 2006

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Article

Thymidine phosphorylase levels and dihydropyrimidine dehydrogenase levels in non-small cell lung cancer tissues

Masao Chujo, Takashi Miura, Yozo Kawano, Michiyo Miyawaki, Takayuki Imakiire, Yoji Hayashita, Katsunobu Kawahara
Pages: 777-780
Published online on: 01 October 2006

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Article

Breast cancer risk and polymorphisms in genes involved in metabolism of estrogens (CYP17, HSD17β1, COMT and MnSOD): Possible protective role of MnSOD gene polymorphism Val/Ala and Ala/Ala in women that never breast fed

Susana N. Silva, Marisa N. Cabral, Guilherme Bezerra de Castro, Marcelo Pires, Ana Paula Azevedo, Isabel Manita, Julieta Esperança Pina, José Rueff, Jorge Gaspar
Pages: 781-788
Published online on: 01 October 2006

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Article

Epidermal growth factor induction of resistance to topoisomerase II toxins in human squamous carcinoma A431 cells

Wing-Pui Tsang, Siu-Kai Kong, Tim-Tak Kwok
Pages: 789-793
Published online on: 01 October 2006

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Article

Disruption of protein-protein interaction in the Mgl-1 oncoprotein

Yong-Soo Kim, Yu-Kyung Kim, Jung-Mi Park, In-Soo Han, Brijesh S. Ajjappala, Incheol Kang, Kwang-Hyun Baek
Pages: 795-800
Published online on: 01 October 2006

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Article

Linkage disequilibrium of UGT1A1∗6 and UGT1A1∗28 in relation to UGT1A6 and UGT1A7 polymorphisms

Naohito Urawa, Yoshinao Kobayashi, Jun Araki, Ryosuke Sugimoto, Motoh Iwasa, Masahiko Kaito, Yukihko Adachi
Pages: 801-806
Published online on: 01 October 2006

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Article

Evaluation of Ki67, p53 and angiogenesis in patients enrolled in a randomized study of neoadjuvant chemotherapy with or without cystectomy: A southwest oncology group study

H. Barton Grossman, Catherine M. Tangen, Carlos Cordon-Cardo, Richard Cote, Frederic M. Waldman, Ralph W. De Vere White, Anand B. Karnad, Michael Glode, E. David Crawford
Pages: 807-810
Published online on: 01 October 2006

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Article

Missense mutations of BRCA1 gene affect the binding with p53 both in vitro and in vivo

Barbara Quaresima, Maria C. Faniello, Francesco Baudi, Telma Crugliano, Maddalena Di Sanzo, Giovanni Cuda, Francesco Costanzo, Salvatore Venuta
Pages: 811-815
Published online on: 01 October 2006

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Article

Genome-wide cDNA microarray screening of genes related to survival in patients after curative resection of non-small cell lung cancer

Fumihiro Oshita, Akiko Sekiyama, Hiroyuki Ito, Yoichi Kameda, Yohei Miyagi
Pages: 817-821
Published online on: 01 October 2006

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Article

Relationship between E-cadherin, matrix metalloproteinase-7 gene expression and clinicopathological features in gastric carcinoma

Kyung Hee Lee, Sang Joon Shin, Kyeong Ok Kim, Min Kyoung Kim, Myung Soo Hyun, Tae Nyeun Kim, Byung Ik Jang, Sang Woon Kim, Sun Kyo Song, Hee Sun Kim, Sung Hwa Bae, Hun Mo Ryoo
Pages: 823-830
Published online on: 01 October 2006

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Article

Androgen receptor negatively influences the expression of chemokine receptors (CXCR4, CCR1) and ligand-mediated migration in prostate cancer DU-145

Takuya Akashi, Keiichi Koizumi, Osamu Nagakawa, Hideki Fuse, Ikuo Saiki
Pages: 831-836
Published online on: 01 October 2006

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Article

Aging of patients with hepatitis C virus-associated hepatocellular carcinoma: Long-term trends in Japan

Naota Taura, Keisuke Hamasaki, Kazuhiko Nakao, Tatsuki Ichikawa, Daisuke Nishimura, Takashi Goto, Mariko Fukuta, Hiroshi Kawashimo, Hisamitsu Miyaaki, Masumi Fujimoto, Kouichiro Kusumoto, Yasuhide Motoyoshi, Hidetaka Shibata, Kaoru Inokuchi, Katsumi Eguchi
Pages: 837-843
Published online on: 01 October 2006

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Article

MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers

Yukihiro Akao, Yoshihito Nakagawa, Tomoki Naoe
Pages: 845-850
Published online on: 01 October 2006

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Article

Regulatory roles of cell surface sialylation in sphingolipid-induced cell death in human B cell lymphoma

Osamu Suzuki, Yoshihiro Nozawa, Masafumi Abe
Pages: 851-857
Published online on: 01 October 2006

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Article

skewed X chromosome inactivation of blood cells is associated with early development of lung cancer in females

Gang Li, Qin Su, Gui-Qiu Liu, Li Gong, Wei Zhang, Shao-Jun Zhu, He-Long Zhang, Ying-Ming Feng
Pages: 859-864
Published online on: 01 October 2006

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Article

Alternating hepatic arterial infusion and systemic chemotherapy for stage IV colorectal cancer with synchronous liver metastasis

Masaya Mukai, Yasuhisa Oida, Takayuki Tajima, Kyoko Kishima, Hiromi Ninomiya, Shinkichi Sato, Masato Nakamura, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 865-870
Published online on: 01 October 2006

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Article

Analgesic activity of high-dose intravenous calcitonin in cancer patients with bone metastases

Nicolas Tsavaris, Petros Kopterides, Christos Kosmas, Maria Vadiaka, Antonios Dimitrakopoulos, Helias Scopelitis, Roxanni Tenta, George Vaiopoulos, Christos Koufos
Pages: 871-875
Published online on: 01 October 2006

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Article

A phase II trial with gemcitabine and paclitaxel for the treatment of refractory and relapsed multiple myeloma patients

Yair Gazitt, Paul Shaughnessy, Mace L. Rothenberg
Pages: 877-884
Published online on: 01 October 2006

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Article

Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer

Hernán G. Farina, Monica Pomies, Daniel F. Alonso, Daniel E. Gomez
Pages: 885-891
Published online on: 01 October 2006

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Article

Proliferation studies on chromosome preparations of bone marrow in hematological disease

J.-U. Walther, I. Pohl, A. Rausch, M. Fuehrer
Pages: 893-899
Published online on: 01 October 2006

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Article

Time course of enhanced activity of deoxycytidine kinase and thymidine kinase 1 and 2 in cultured human squamous lung carcinoma cells, SW-1573, induced by γ-irradiation

J. Haveman, J. Sigmond, C. van Bree, N. A. Franken, C. Koedooder, G. J. Peters
Pages: 901-905
Published online on: 01 October 2006

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Article

Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells

Lihua Qiu, Changlin Zhou, Yun Sun, Wen Di, Erica Scheffler, Sarah Healey, Harold Wanebo, Nicola Kouttab, Wenming Chu, Yinsheng Wan
Pages: 907-913
Published online on: 01 October 2006

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Article

Allelic loss of Hox11L1 gene locus predicts outcome of gastrointestinal stromal tumors

Jussuf T. Kaifi, Meike Wagner, Paulus G. Schurr, Robin Wachowiak, Uta Reichelt, Emre F. Yekebas, Oliver Mann, Yogesh Vashist, Helge Kleinhans, Bjoern-Christian Link, Tim Strate, Viacheslav Kalinin, Jakob R. Izbicki
Pages: 915-919
Published online on: 01 October 2006

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Article

Inhibitory effect of ailanthoidol on 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion in mouse skin

Yean-Jang Lee, Erl-Shyh Kao, Chia-Yih Chu, Wea-Lung Lin, Yea-Huey Chiou, Tsui-Hwa Tseng
Pages: 921-927
Published online on: 01 October 2006

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Article

Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1α

Hyo-Eun Moon, Hwanju Cheon, Kwang-Hoon Chun, Seung Ki Lee, Yong-Sik Kim, Bo-Kyung Jung, Jeong Ae Park, Se-Hee Kim, Joo-Won Jeong, Myung-Shik Lee
Pages: 929-935
Published online on: 01 October 2006

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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