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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2007 Volume 17 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Epigenetic DNA-methylation regulation of genes coding for lipid raft-associated components: A role for raft proteins in cell transformation and cancer progression (Review)

Samir K. Patra, Saverio Bettuzzi
Pages: 1279-1290
Published online on: 01 June 2007

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Article

Oral Kaposi's sarcoma in Tanzania: Presentation, immunopathology and human herpesvirus-8 association

Amos R. Mwakigonja, Fatemeh Pak, Pawan Pyakurel, Innocent J. Mosha, Willy K. Urassa, Ephata E. Kaaya, Peter Biberfeld
Pages: 1291-1299
Published online on: 01 June 2007

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Article

Overexpression of SPARC protein contrasts with its transcriptional silencing by aberrant hypermethylation of SPARC CpG-rich region in endometrial carcinoma

Francisco-Javier Rodríguez-Jiménez, Trinidad Caldés, Pilar Iniesta, Jose Antonio Vidart, José López Garcia-Asenjo, Manuel Benito
Pages: 1301-1307
Published online on: 01 June 2007

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Article

Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma

Takahiro Noda, Takashi Kumada, Shinji Takai, Rie Matsushima-Nishiwaki, Naoki Yoshimi, Eisuke Yasuda, Kanefusa Kato, Hidenori Toyoda, Yuji Kaneoka, Akihiro Yamaguchi, Osamu Kozawa
Pages: 1309-1314
Published online on: 01 June 2007

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Article

Purification of human primary neuroblastomas by magnetic beads and their in vitro culture

Hiroko Nakanishi, Toshinori Ozaki, Youko Nakamura, Kohei Hashizume, Tadashi Iwanaka, Akira Nakagawara
Pages: 1315-1320
Published online on: 01 June 2007

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Article

HPV infection and the alterations of the pRB pathway in oral carcinogenesis

Kue Peng Lim, Sharifah Hamid, Shin-Hin Lau, Soo-Hwang Teo, Sok Ching Cheong
Pages: 1321-1326
Published online on: 01 June 2007

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Article

Predictive value of vascular endothelial growth factor-C expression for local recurrence of rectal carcinoma

Eiji Noda, Kiyoshi Maeda, Toru Inoue, Tamahiro Nishihara, Yukio Nishiguchi, Masaichi Ohira, Kosei Hirakawa
Pages: 1327-1331
Published online on: 01 June 2007

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Article

Increased synthesis of indoleamine-2,3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer

Miho Takao, Aikou Okamoto, Takashi Nikaido, Mitsuyoshi Urashima, Satoshi Takakura, Misato Saito, Motoaki Saito, Sanshiro Okamoto, Osamu Takikawa, Hiroshi Sasaki, Makoto Yasuda, Kazunori Ochiai, Tadao Tanaka
Pages: 1333-1339
Published online on: 01 June 2007

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Article

Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo

Xuerui Zhou, Xiuling Zhi, Ping Zhou, Sifeng Chen, Fengdi Zhao, Zhimin Shao, Zhouluo Ou, Lianhua Yin
Pages: 1341-1346
Published online on: 01 June 2007

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Article

Expression of the Epstein-Barr virus in lymphoproliferative diseases of the lung

Misuzu Shimakage, Haruhiko Sakamoto, Shizuko Harada, Toshiyuki Sasagawa, Ken Kodama
Pages: 1347-1352
Published online on: 01 June 2007

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Article

A reduced COX-2 expression and a reduced number of pericryptal myofibroblasts are associated with depressed adenoma of the colon

Katsunori Harada, Shingo Higaki, Ayaka Amano, Kazuo Hashimoto, Shinichi Hashimoto, Toshikazu Gondo, Isao Sakaida
Pages: 1353-1358
Published online on: 01 June 2007

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Article

Radiotherapy plus concurrent and adjuvant procarbazine, lomustine, and vincristine chemotherapy for patients with malignant glioma

Seung-Ho Yang, Yong-Kil Hong, Sei-Chul Yoon, Bum-Soo Kim, Youn-Soo Lee, Tae-Kyu Lee, Kwan-Sung Lee, Sin-Soo Jeun, Moon-Chan Kim, Chun-Kun Park
Pages: 1359-1364
Published online on: 01 June 2007

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Article

Local recurrence and occult neoplastic cells in the extranodal fat of dissected lymph nodes in patients with curatively resected primary colorectal cancer

Masaya Mukai, Masato Nakamura, Kyoko Kishima, Hiromi Ninomiya, Nozomi Nomura, Hisayoshi Sato, Nobuaki Kato, Tomohisa Machida, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1365-1369
Published online on: 01 June 2007

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Article

Activation of human natural killer cells by recombinant membrane-expressed fractalkine on the surface of tumor cells

Xiaojun Zhang, Haiming Wei, Qingfeng Chen, Zhigang Tian
Pages: 1371-1375
Published online on: 01 June 2007

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Article

STAT3-decoy oligodeoxynucleotide inhibits the growth of human lung cancer via down-regulating its target genes

Xulong Zhang, Jian Zhang, Haiming Wei, Zhigang Tian
Pages: 1377-1382
Published online on: 01 June 2007

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Article

Biphasic expression of RhoGDI2 in the progression of breast cancer and its negative relation with lymph node metastasis

Li De Hu, Hua Fei Zou, Shu Xuan Zhan, Kai Ming Cao
Pages: 1383-1389
Published online on: 01 June 2007

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Article

Inhibition of tumor growth and tumor metastasis by a Chinese herbal formula - ZYD88, in an animal model with metastatic Lewis lung carcinoma

Yan-Wen Duan, Ying Huang, Li-Qun Cai, Quwen Duan, Yuan-Shan Zhu
Pages: 1391-1397
Published online on: 01 June 2007

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Article

The non-competitive metabotropic glutamate receptor-1 antagonist CPCCOEt inhibits the in vitro growth of human melanoma

Helga Susanne Haas, Roswitha Pfragner, Veronika Siegl, Elisabeth Ingolic, Elfgard Heintz, Elisabeth Schraml, Konrad Schauenstein
Pages: 1399-1404
Published online on: 01 June 2007

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Article

EGFR activating aberration occurs independently of other genetic aberrations or telomerase activation in adenocarcinoma of the lung

Marina Arifin, Keiko Hiyama, Keiji Tanimoto, Wiwien Heru Wiyono, Eiso Hiyama, Masahiko Nishiyama
Pages: 1405-1411
Published online on: 01 June 2007

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Article

VEGF transcription and mRNA stability are altered by WT1 not DDS(R384W) expression in LNCaP cells

Jennifer Cash, Amanda Korchnak, Jacquelyn Gorman, Yasmeen Tandon, Gail Fraizer
Pages: 1413-1419
Published online on: 01 June 2007

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Article

O6-methylguanine-DNA methyltransferase promoter hypermethylation in colorectal carcinogenesis

Mirco Menigatti, Monica Pedroni, Anna Maria Verrone, Francesca Borghi, Alessandra Scarselli, Piero Benatti, Lorena Losi, Carmela Di Gregorio, Primo Schär, Giancarlo Marra, Maurizio Ponz de Leon, Luca Roncucci
Pages: 1421-1427
Published online on: 01 June 2007

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Article

Enhancement of lymphokine-activated killer cell induction using anti-CD25 and anti-CTLA-4 monoclonal antibodies

Riki Okita, Yoshiyuki Yamaguchi, Akiko Emi, Kazuo Matsuura, Tetsuya Toge
Pages: 1429-1435
Published online on: 01 June 2007

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Article

Timing of apoptosis onset depends on cell cycle progression in peripheral blood lymphocytes and lymphocytic leukemia cells

Yongdong Feng, Jianhong Wu, Xiaolan Feng, Deding Tao, Junbo Hu, Jichao Qin, Xiaolan Li, Wei Xiao, Kevin Gardner, Susan I.V. Judge, Qingdi Q. Li, Jianping Gong
Pages: 1437-1444
Published online on: 01 June 2007

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Article

Down-regulation of the nuclear factor-κB by lidamycin in association with inducing apoptosis in human pancreatic cancer cells and inhibiting xenograft growth

Jing Chen, Zhi-gang Ouyang, Sheng-hua Zhang, Yong-su Zhen
Pages: 1445-1451
Published online on: 01 June 2007

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Article

Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil

Hiromi Kazuno, Yuji Shimamoto, Hiroaki Tsujimoto, Masakazu Fukushima, Akira Matsuda, Takuma Sasaki
Pages: 1453-1460
Published online on: 01 June 2007

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Article

Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines

Jun Murakami, You-Jin Lee, Susumu Kokeguchi, Hidetsugu Tsujigiwa, Jun-Ichi Asaumi, Hitoshi Nagatsuka, Kazuhiro Fukui, Masahiro Kuroda, Noriaki Tanaka, Nagahide Matsubara
Pages: 1461-1467
Published online on: 01 June 2007

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Article

Significance of target cell infection and natural killer cells in the anti-tumor effects of bacillus Calmette-Guerin in murine bladder cancer

Teppei Sonoda, Kazunobu Sugimura, Shin-Ichi Ikemoto, Hidenori Kawashima, Tatsuya Nakatani
Pages: 1469-1474
Published online on: 01 June 2007

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Article

Sentinel lymph node detection using computed tomography lymphography is accurate after neoadjuvant chemotherapy for breast cancer

Hironobu Ue, Yasuhiro Ogawa, Shinji Kariya, Kimiko Nakatani, Kazuhiro Tsuzuki, Kana Miyatake, Hironori Maeda, Yosuke Tanaka, Shiro Sasaguri
Pages: 1475-1480
Published online on: 01 June 2007

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Article

GADD34 induces p21 expression and cellular senescence

Kahori Minami, Hirokazu Inoue, Takao Terashita, Takahiro Kawakami, Ryosuke Watanabe, Masataka Haneda, Ken-Ichi Isobe, Hidetoshi Okabe, Tokuhiro Chano
Pages: 1481-1485
Published online on: 01 June 2007

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Article

Effects of crude aqueous medicinal plant extracts on growth and invasion of breast cancer cells

Severine van Slambrouck, Amber L. Daniels, Carla J. Hooten, Steven L. Brock, Aaron R. Jenkins, Marcia A. Ogasawara, Joann M. Baker, Glen Adkins, Eerik M. Elias, Vincent J. Agustin, Sarah R. Constantine, Michael J. Pullin, Scott T. Shors, Alexander Kornienko, Wim F.A. Steelant
Pages: 1487-1492
Published online on: 01 June 2007

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Article

Combined oncolytic and vaccination activities of parvovirus H-1 in a metastatic tumor model

Zahari Raykov, Svetlana Grekova, Angel S. Galabov, Ginette Balboni, Ute Koch, Marc Aprahamian, Jean Rommelaere
Pages: 1493-1499
Published online on: 01 June 2007

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Article

Additive viability-loss following hsp70/hsc70 double interference and Hsp90 inhibition in two breast cancer cell lines

Bjarte Håvik, Clive R. Bramham
Pages: 1501-1510
Published online on: 01 June 2007

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Article

CCL21 promotes the migration and adhesion of highly lymph node metastatic human non-small cell lung cancer Lu-99 in vitro

Keiichi Koizumi, Yoko Kozawa, Yasukata Ohashi, Eliane Shizuka Nakamura, Yasushi Aozuka, Hiroaki Sakurai, Katsuyuki Ichiki, Yoshinori Doki, Takuro Misaki, Ikuo Saiki
Pages: 1511-1516
Published online on: 01 June 2007

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Article

Onopordum cynarocephalum induces apoptosis and protects against 1,2 dimethylhydrazine-induced colon cancer

Nahed El-Najjar, Najat Saliba, Salma Talhouk, Hala Gali-Muhtasib
Pages: 1517-1523
Published online on: 01 June 2007

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Article

Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis

Susan Cheung, Joseph Tai
Pages: 1525-1531
Published online on: 01 June 2007

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Article

Short-term effects of pamidronate on bone turnover: Can bone markers be considered predictive of the analgesic response?

A. Martinetti, C. Ripamonti, R. Miceli, E. Seregni, L. Mariani, F. De Conno, E. Bajetta, E. Bombardieri
Pages: 1533-1540
Published online on: 01 June 2007

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Article

Genome wide expression profiling identifies genes associated with colorectal liver metastasis

H.-M. Lin, A. Chatterjee, Y.-H. Lin, A. Anjomshoaa, R. Fukuzawa, J. L. McCall, A. E. Reeve
Pages: 1541-1549
Published online on: 01 June 2007

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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