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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2010 Volume 23 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Anticancer bioactive peptide suppresses human gastric cancer growth through modulation of apoptosis and the cell cycle

Liya Su, Guihua Xu, Jie Shen, Ya Tuo, Xingguang Zhang, Shuqin Jia, Zhong Chen, Xiulan Su
Pages: 3-9
Published online on: 01 January 2010

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Article

The ubiquitin-like molecule interferon-stimulated gene 15 is overexpressed in human prostate cancer

Hirofumi Satake, Kenji Tamura, Mutsuo Furihata, Takashi Anchi, Hatsune Sakoda, Chiaki Kawada, Tatsuo Iiyama, Shingo Ashida, Taro Shuin
Pages: 11-16
Published online on: 01 January 2010

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Article

The stem cell marker nestin predicts poor prognosis in human melanoma

Franca Piras, Maria Teresa Perra, Daniela Murtas, Luigi Minerba, Carlo Floris, Cristina Maxia, Paolo Demurtas, Jorge Ugalde, Domenico Ribatti, Paola Sirigu
Pages: 17-24
Published online on: 01 January 2010

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Article

Molecular analysis of single isolated glands in gastric cancers and their surrounding gastric intestinal metaplastic mucosa

Tamotsu Sugai, Wataru Habano, Yu-Fei Jiao, Minoru Toyota, Hiromu Suzuki, Mitsunori Tsukahara, Hitohiko Koizuka, Risaburo Akasaka, Keisuke Koeda, Go Wakabayashi, Kazuyuki Suzuki
Pages: 25-33
Published online on: 01 January 2010

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Article

Notch pathway as candidate therapeutic target in Her2/Neu/ErbB2 receptor-negative breast tumors

Hajime Hirose, Hideshi Ishii, Koshi Mimori, Daisuke Ohta, Masahisa Ohkuma, Hirohiko Tsujii, Toshiyuki Saito, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori
Pages: 35-43
Published online on: 01 January 2010

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Article

Expression status of S100A14 and S100A4 correlates with metastatic potential and clinical outcome in colorectal cancer after surgery

Hong-Yi Wang, Jing-Yu Zhang, Jian-Tao Cui, Xiao-Hui Tan, Wen-Mei Li, Jin Gu, You-Yong Lu
Pages: 45-52
Published online on: 01 January 2010

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Article

Chemopreventive effect of fermented brown rice and rice bran (FBRA) on the inflammation-related colorectal carcinogenesis in ApcMin/+ mice

Suphot Phutthaphadoong, Yasuhiro Yamada, Akihiro Hirata, Hiroyuki Tomita, Akira Hara, Pornngarm Limtrakul, Teruaki Iwasaki, Hiroshi Kobayashi, Hideki Mori
Pages: 53-59
Published online on: 01 January 2010

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Article

State of homeobox A10 expression as a putative prognostic marker for oral squamous cell carcinoma

Masanobu Yamatoji, Atsushi Kasamatsu, Yukio Yamano, Kentaro Sakuma, Kenji Ogoshi, Manabu Iyoda, Keiji Shinozuka, Katsunori Ogawara, Yuichi Takiguchi, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa
Pages: 61-67
Published online on: 01 January 2010

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Expression of matrix metalloproteinase-26 promotes human glioma U251 cell invasion in vitro and in vivo

Yiping Deng, Wei Li, Yilei Li, Hongfa Yang, Hua Xu, Shanshan Liang, Lihong Zhang, Yulin Li
Pages: 69-78
Published online on: 01 January 2010

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Article

Na+/H+ exchanger blockade inhibits the expression of vascular endothelial growth factor in SGC7901 cells

Bingyan He, Ming Zhang, Rui Zhu
Pages: 79-87
Published online on: 01 January 2010

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Article

Effects and action mechanism of Diospyros kaki on the differentiation of human leukemia HL-60 cells

Seung Hyun Kim, Seung Sik Cho, Jaya Ram Simkhada, Sung Ju Park, Hyo Jeong Lee, Tae Sung Kim, Jin Cheol Yoo
Pages: 89-95
Published online on: 01 January 2010

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Article

Enhanced tumor radiosensitivity by a survivin dominant-negative mutant

Qing-Zhong Yuan, Chun-Ting Wang, Yong-Qiu Mao, Peng Zhang, Hua-Shan Shi, Zhi-Yong Li, Li Pan, Dan-Dan Yu, Fei Leng, Xiang Chen, Wei Ying, Jing-Hui Xu, Wei Li, Fan Wu, Yuan Wen, Tian-Tai Ma, Yu-Quan Wei
Pages: 97-103
Published online on: 01 January 2010

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Article

Isolation and characterization of lymphatic endothelial cells from human glossal lymphangioma

Lanying You, Mingfu Wu, Ying Chen, Gang Xu, Juncheng Wei, Qiong Li, Anping Song, Liangpin Zhao, Shuang Li, Zhiqiang Han, Jianfeng Zhou, Yunpin Lu, Shixuan Wang, Ding Ma, Li Meng
Pages: 105-111
Published online on: 01 January 2010

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Article

High expression of microRNA-15b predicts a low risk of tumor recurrence following curative resection of hepatocellular carcinoma

Goh Eun Chung, Jung-Hwan Yoon, Sun Jung Myung, Jeong-Hoon Lee, Sung-Hee Lee, Soo-Mi Lee, Seung-Jun Kim, Seung Yong Hwang, Hyo-Suk Lee, Chung Yong Kim
Pages: 113-119
Published online on: 01 January 2010

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Article

5-Fluorouracil and oxaliplatin modify the expression profiles of microRNAs in human colon cancer cells in vitro

Jianfeng Zhou, Yanping Zhou, Bin Yin, Wei Hao, Lin Zhao, Wenyi Ju, Chunmei Bai
Pages: 121-128
Published online on: 01 January 2010

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Article

Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells

Haitao Zhu, Jicui Zheng, Xianmin Xiao, Shan Zheng, Kuiran Dong, Jiangbin Liu, Yang Wang
Pages: 129-139
Published online on: 01 January 2010

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Article

Co-elevated expression of hepatocyte growth factor and interleukin-8 contributes to poor prognosis of patients with primary nasopharyngeal carcinoma

Li-Qiong Xie, Li-Juan Bian, Zhi Li, Yang Li, Ying-Jie Liang
Pages: 141-150
Published online on: 01 January 2010

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Article

The mitogenic effectors of isoproterenol in human hepatocellular carcinoma cells

Aihua Yuan, Zongfang Li, Xinqiu Li, Shanyong Yi, Shukui Wang, Yongdong Cai, Hongyong Cao
Pages: 151-157
Published online on: 01 January 2010

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Article

Activation of mTOR in renal cell carcinoma is due to increased phosphorylation rather than protein overexpression

Stephan Kruck, Jens Bedke, Jörg Hennenlotter, Petra A. Ohneseit, Ursula Kuehs, Erika Senger, Karl-Dietrich Sievert, Arnulf Stenzl
Pages: 159-163
Published online on: 01 January 2010

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Article

Etoposide induces growth arrest and disrupts androgen receptor signaling in prostate cancer cells

Shicheng Liu, Hitoshi Yamauchi
Pages: 165-170
Published online on: 01 January 2010

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Article

Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatin

Patrizia Gazzerro, Anna M. Malfitano, Maria Chiara Proto, Antonietta Santoro, Simona Pisanti, Maria Gabriella Caruso, Maria Notarnicola, Caterina Messa, Chiara Laezza, Gabriella Misso, Michele Caraglia, Maurizio Bifulco
Pages: 171-175
Published online on: 01 January 2010

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Article

Wnt-5a regulates proliferation in lung cancer cells

Ying Huang, Guangxiang Liu, Bo Zhang, Gang Xu, Wei Xiong, Heping Yang
Pages: 177-181
Published online on: 01 January 2010

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Article

Down-regulation of MTUS1 in human colon tumors

Christina Zuern, Jutta Heimrich, Roland Kaufmann, Konrad K. Richter, Utz Settmacher, Christoph Wanner, Jan Galle, Stefan Seibold
Pages: 183-189
Published online on: 01 January 2010

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Article

CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients

Masatsugu Hiraki, Yoshihiko Kitajima, Yuji Nakafusa, Jun Nakamura, Kazuyoshi Hashiguchi, Kenji Sumi, Hirokazu Noshiro, Kohji Miyazaki
Pages: 191-197
Published online on: 01 January 2010

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Article

p53 independent radio-sensitization of human lymphoblastoid cell lines by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin

Yoshihiro Fujii, Takamitsu Kato, Nobuo Kubota, Akira Fujimori, Ohtsura Niwa, Ryuichi Okayasu
Pages: 199-203
Published online on: 01 January 2010

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Article

Anti-tumor effects of AMT in the renal cell carcinoma model

Marcello Caballero, Jürgen Scheele, Ute Zirrgiebel, Norbert Esser, Christoph Schächtele, Jens Soltau, Jochen Rentschler, Klaus Diergarten, Joachim Drevs
Pages: 205-210
Published online on: 01 January 2010

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Article

Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells

Xuan-Bin Wang, Shan-Shan Wang, Qiu-Fang Zhang, Ming Liu, Hong-Liang Li, Ying Liu, Jia-Ning Wang, Fei Zheng, Ling-Yun Guo, Ji-Zhou Xiang
Pages: 211-215
Published online on: 01 January 2010

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Article

Imatinib mesylate (STI571) enhances amrubicin-induced cytotoxic activity through inhibition of the phosphatidylinositol 3-kinase/Akt pathway in small cell lung cancer cells

Hisashi Suyama, Tadashi Igishi, Yasuto Ueda, Yasushi Shigeoka, Masahiro Kodani, Masato Morita, Kenichi Takeda, Takashi Sumikawa, Hirofumi Nakazaki, Keiji Matsunami, Shingo Matsumoto, Eiji Shimizu
Pages: 217-222
Published online on: 01 January 2010

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Article

ERCC1 and XPF expression in human testicular germ cell tumors

Beate Köberle, Walburgis Brenner, Andreas Albers, Svetlana Usanova, Joachim W. Thüroff, Bernd Kaina
Pages: 223-227
Published online on: 01 January 2010

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Article

The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression

Jongkyu Lee, Cheol Hwangbo, Jung Joon Lee, Juhee Seo, Jeong-Hyung Lee
Pages: 229-237
Published online on: 01 January 2010

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Article

Involvement of p21Waf1/Cip1 cleavage during roscovitine-induced apoptosis in non-small cell lung cancer cells

Tao Zhang, Tao Jiang, Feng Zhang, Chen Li, Yong-An Zhou, Yi-Fang Zhu, Xiao-Fei Li
Pages: 239-245
Published online on: 01 January 2010

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Article

Vascular damage in testicular cancer patients: A study on endothelial activation by bleomycin and cisplatin in vitro

Janine Nuver, Esther C. De Haas, Martine Van Zweeden, Jourik A. Gietema, Coby Meijer
Pages: 247-253
Published online on: 01 January 2010

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Article

Hypoxia activates heparanase expression in an NF-κB dependent manner

Wujun Wu, Cheng'en Pan, Kewei Meng, Lin Zhao, Lixue Du, Qingguang Liu, Rong Lin
Pages: 255-261
Published online on: 01 January 2010

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Article

HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA double-strand break repair capacity

Jan C. Purrucker, Andreas Fricke, Mei Fang Ong, Christian Rübe, Claudia E. Rübe, Ulrich Mahlknecht
Pages: 263-269
Published online on: 01 January 2010

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Article

Association of the ABCB1 3435C>T polymorphism and treatment outcomes in advanced gastric cancer patients treated with paclitaxel-based chemotherapy

Hyun Chang, Sun Young Rha, Hei-Cheul Jeung, Chong Kun Im, Sung Hoon Noh, Jin Ju Kim, Hyun Cheol Chung
Pages: 271-278
Published online on: 01 January 2010

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Article

Resveratrol down-regulates survivin and induces apoptosis in human multidrug-resistant SPC-A-1/CDDP cells

Weiguo Zhao, Pengtao Bao, Haowen Qi, Houcheng You
Pages: 279-286
Published online on: 01 January 2010

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Article

Pyrogallol-induced endothelial cell death is related to GSH depletion rather than ROS level changes

Yong Hwan Han, Hwa Jin Moon, Bo Ra You, Sung Zoo Kim, Suhn Hee Kim, Woo Hyun Park
Pages: 287-292
Published online on: 01 January 2010

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

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Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

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Article Open Access

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