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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2010 Volume 24 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Nutrition in oncology: the case of micronutrients (Review)

Alexander Ströhle, Kurt Zänker, Andreas Hahn
Pages: 815-828
Published online on: 01 October 2010

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Article Open Access

Pathotropic targeting advances clinical oncology: Tumor-targeted localization of therapeutic gene delivery

Frederick L. Hall, John P. Levy, Rebecca A. Reed, Wasinee N. Petchpud, Victoria S. Chua, Sant P. Chawla, Erlinda M. Gordon
Pages: 829-833
Published online on: 01 October 2010

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Article

Irinotecan overcomes the resistance to 5-fluorouracil in human colon cancer xenografts by down-regulation of intratumoral thymidylate synthase

Masakazu Fukushima, Kazuki Sakamoto, Hideyuki Ohshimo, Fumio Nakagawa, Tetsuo Taguchi
Pages: 835-842
Published online on: 01 October 2010

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Article Open Access

Anti-tumor effect by inhibition of NF-κB activation using nafamostat mesilate for pancreatic cancer in a mouse model

Kenei Furukawa, Tomonori Iida, Hiroaki Shiba, Yuki Fujiwara, Tadashi Uwagawa, Yohta Shimada, Takeyuki Misawa, Toya Ohashi, Katsuhiko Yanaga
Pages: 843-850
Published online on: 01 October 2010

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Article

p53 mutation, but not in vitro predictor genes of therapeutic efficacy of cisplatin, is clinically relevant in comparing partial and complete responder cases of maxillary squamous cell carcinoma

Itsuhiro Kudo, Mariko Esumi, Akihiro Kida, Minoru Ikeda
Pages: 851-856
Published online on: 01 October 2010

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Article

A new approach to concordance in mid-infrared spectromicroscopy mapping of malignant tumors

Kaiser Ali, Todd Reichert, Daniel Gomez, Yanjie Lu, Alexander Jan, Colleen Christensen
Pages: 857-860
Published online on: 01 October 2010

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Article

CD98 expression is associated with the grade of malignancy in thymic epithelial tumors

Kyoichi Kaira, Toshiaki Takahashi, Masato Abe, Hiroaki Akamatsu, Kazuo Nakagawa, Yasuhisa Ohde, Takehiro Okumura, Haruyasu Murakami, Asuka Tsuya, Yukiko Nakamura, Tateaki Naito, Haruhiko Kondo, Takashi Nakajima, Masahiro Endo, Nobuyuki Yamamoto
Pages: 861-867
Published online on: 01 October 2010

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Article

Increased apoptosis and decreased proliferation of colonic epithelium in dextran sulfate sodium-induced colitis in mice

Yoshio Araki, Ken-Ichi Mukaisyo, Hiroyuki Sugihara, Yoshihide Fujiyama, Takanori Hattori
Pages: 869-874
Published online on: 01 October 2010

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Article

DNA copy number aberrations associated with aneuploidy and chromosomal instability in breast cancers

Shigeto Kawauchi, Tomoko Furuya, Kenzo Ikemoto, Motonao Nakao, Shigeru Yamamoto, Masaaki Oka, Kohsuke Sasaki
Pages: 875-883
Published online on: 01 October 2010

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Article

Genetic profiles distinguish different types of hereditary ovarian cancer

Katarina Domanska, Susanne Malander, Johan Staaf, Anna Karlsson, Åke Borg, Göran Jönsson, Mef Nilbert
Pages: 885-895
Published online on: 01 October 2010

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Article

High-level transgene expression mediated by the piggyBac transposon enhances transgenic therapeutic effects in cervical cancer xenografts

Yu Kang, Wenbo Yu, Qinwen Sun, Xiaoyan Zhang, Wei Jiang, Chaoqun Wu, Chunmei Chen, Jianren Gu, Yufang Zheng, Congjian Xu
Pages: 897-907
Published online on: 01 October 2010

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Article

Elevated L1CAM expression in precursor lesions and primary and metastastic tissues of pancreatic ductal adenocarcinoma

Frank Bergmann, Frauke Wandschneider, Bence Sipos, Gerhard Moldenhauer, Bodo Schniewind, Thilo Welsch, Peter Schirrmacher, Günter Klöppel, Peter Altevogt, Heiner Schäfer, Susanne Sebens Müerköster
Pages: 909-915
Published online on: 01 October 2010

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Article

High-throughput DNA hypermethylation profiling in different ovarian epithelial cancer subtypes using universal bead array

Man Soo Yoon, Dong Soo Suh, Kyung Un Choi, Mee Young Sol, Dong Hoon Shin, Won Young Park, Jung Hee Lee, Seong Muk Jeong, Woo Gyeong Kim, Na Ri Shin
Pages: 917-925
Published online on: 01 October 2010

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Article

Microsatellite instability and hMLH1 and hMSH2 expression in renal tumors

Giuseppe Altavilla, Matteo Fassan, Graziella Busatto, Martina Orsolan, Luciano Giacomelli
Pages: 927-932
Published online on: 01 October 2010

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Article

C4orf7 contributes to ovarian cancer metastasis by promoting cancer cell migration and invasion

Changyu Wang, Li Zhou, Shuang Li, Juncheng Wei, Wei Wang, Ting Zhou, Shujie Liao, Danhui Weng, Dongrui Deng, Yanjie Weng, Shixuan Wang, Ding Ma
Pages: 933-939
Published online on: 01 October 2010

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Article

The antitumor and antimetastatic effects of N-trimethyl chitosan-encapsulated camptothecin on ovarian cancer with minimal side effects

Lina Zhou, Licheng Du, Xiancheng Chen, Xingyi Li, Zhiyong Li, Yuan Wen, Zhengyu Li, Xiang He, Yuquan Wei, Xia Zhao, Zhiyong Qian
Pages: 941-948
Published online on: 01 October 2010

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Article

14-3-3σ expression as a prognostic marker in undifferentiated nasopharyngeal carcinoma

Sylvia Yat-Yee Chan, Ka-Fai To, Sing-Fai Leung, William Wai-Lun Yip, Michael Ko-Fung Mak, Grace Tin-Yun Chung, Kwok-Wai Lo
Pages: 949-955
Published online on: 01 October 2010

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Article

Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer

Hyunseung Lee, Ju-Hee Lee, Kyung Hee Jung, Soon-Sun Hong
Pages: 957-963
Published online on: 01 October 2010

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Article

Role for ezrin in breast cancer cell chemotaxis to CCL5

Juanjuan Li, Yi Tu, Jing Wen, Feng Yao, Wen Wei, Shengrong Sun
Pages: 965-971
Published online on: 01 October 2010

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Article

Thermoseed hyperthermia treatment of mammary orthotopic transplantation tumors in rats and impact on immune function

Weiwei Ouyang, Fuping Gao, Lufang Wang, Xiaoxue Xie, Fenglin Lei, Jumei Zhou, Yuping Liao, Meizuo Zhong, Jintian Tang
Pages: 973-979
Published online on: 01 October 2010

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Article

SATB1 is an independent prognostic marker for gastric cancer in a Chinese population

Xiaoming Lu, Chao Cheng, Shikai Zhu, Yun Yang, Liduan Zheng, Guobin Wang, Xiaogang Shu, Ke Wu, Ke Liu, Qiang Tong
Pages: 981-987
Published online on: 01 October 2010

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Article

The chemokine receptor 7 regulates cell adhesion and migration via β1 integrin in metastatic squamous cell carcinoma of the head and neck

Peng Li, Zhen-Jin Zhao, Fa-Yu Liu, Li-Yan Sun, Xue Ding, Wen-Zhong Zhang, De-Hao Shang, Chang-Fu Sun
Pages: 989-995
Published online on: 01 October 2010

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Article

A pivotal role for Pim-1 kinase in esophageal squamous cell carcinoma involving cell apoptosis induced by reducing Akt phosphorylation

Shenglei Li, Yu Xi, Hongyan Zhang, Yange Wang, Xin Wang, Hongtao Liu, Kuisheng Chen
Pages: 997-1004
Published online on: 01 October 2010

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Article

RhoA protein is generally distributed in the nuclei of cancer cells

Yueying Li, Yongchang Chen, Yan Tao, Jin Xu, Miao Chen
Pages: 1005-1009
Published online on: 01 October 2010

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Article Open Access

Acquired resistance to miriplatin in rat hepatoma AH109A/MP10 is associated with increased Bcl-2 expression, leading to defects in inducing apoptosis

Mitsuharu Hanada, Hideo Takasu, Makoto Kitaura
Pages: 1011-1018
Published online on: 01 October 2010

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Article

VEGFR and EGFR inhibition increases epithelial cellular characteristics and chemotherapy sensitivity in mesenchymal bladder cancer cells

Yuan Li, Xiaoping Yang, Lih-Jen Su, Thomas W. Flaig
Pages: 1019-1028
Published online on: 01 October 2010

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Article

Possibility of paclitaxel as an alternative radiosensitizer to 5-fluorouracil for colon cancer

Junichiro Hiro, Yasuhiro Inoue, Yuji Toiyama, Shigeyuki Yoshiyama, Koji Tanaka, Yasuhiko Mohri, Chikao Miki, Masato Kusunoki
Pages: 1029-1034
Published online on: 01 October 2010

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Article

WNT pathway in oral cancer: Epigenetic inactivation of WNT-inhibitors

G. Pannone, P. Bufo, A. Santoro, R. Franco, G. Aquino, F. Longo, G. Botti, R. Serpico, B. Cafarelli, A. Abbruzzese, M. Caraglia, S. Papagerakis, L. Lo Muzio
Pages: 1035-1041
Published online on: 01 October 2010

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Article

Up-regulation of NKG2F receptor, a functionally unknown killer receptor, of human natural killer cells by interleukin-2 and interleukin-15

Haihua Huang, Xin Wang, Yukun Zhang, Xiaodong Zheng, Haiming Wei, Rui Sun
Pages: 1043-1048
Published online on: 01 October 2010

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Article

Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy

Alexandra Murray, Samantha J. Little, Paul Stanley, Anthony Maraveyas, Lynn Cawkwell
Pages: 1049-1058
Published online on: 01 October 2010

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Article

Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors Retraction in /10.3892/or.2026.9101

Hao Zhang, Meng-Hua Yang, Jing-Jing Zhao, Ling Chen, Song-Tao Yu, Xu-Dong Tang, Dian-Chun Fang, Shi-Ming Yang
Pages: 1059-1065
Published online on: 01 October 2010

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Article

Establishment of a rhabdomyosarcoma xenograft model in human-adapted mice

Guido Seitz, Matthias Pfeiffer, Jörg Fuchs, Steven W. Warmann, Ivo Leuschner, Christian Vokuhl, Peter Lang, Rupert Handgretinger, Sorin Armeanu-Ebinger
Pages: 1067-1072
Published online on: 01 October 2010

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Article

Association between metalloproteinases 2 and 9 activity and ERK1/2 phosphorylation status in head and neck cancers: An ex vivo study

Werner Garavello, Daniele Maggioni, Gabriella Nicolini, Lorenzo Motta, Giovanni Tredici, Renato Gaini
Pages: 1073-1078
Published online on: 01 October 2010

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Article

The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk

Bruno Costa Gomes, Susana Nunes Silva, Ana Paula Azevedo, Isabel Manita, Octávia Monteiro Gil, Teresa Cruz Ferreira, Edward Limbert, José Rueff, Jorge Francisco Gaspar
Pages: 1079-1085
Published online on: 01 October 2010

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Article

Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro

Zhaoli Dai, Vidhya Nair, Maruf Khan, Henry P. Ciolino
Pages: 1087-1091
Published online on: 01 October 2010

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Article

β-catenin siRNA regulation of apoptosis- and angiogenesis-related gene expression in hepatocellular carcinoma cells: potential uses for gene therapy

Xin-Hong Wang, Xun Sun, Xiang-Wei Meng, Zhi-Wu Lv, Ya-Ju Du, Yan Zhu, Jing Chen, De-Xia Kong, Shi-Zhu Jin
Pages: 1093-1099
Published online on: 01 October 2010

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Article

Predictive significance of the cut-off value of CD20 expression in patients with B-cell lymphoma

Mateja Horvat, Veronika Kloboves Prevodnik, Jaka Lavrencak, Barbara Jezersek Novakovic
Pages: 1101-1107
Published online on: 01 October 2010

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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