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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-February 2002 Volume 9 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

The role of HER-2 oncoprotein in drug-sensitivity in breast cancer (Review)

R. Kim, K. Tanabe, Y. Uchida, A. Osaki, T. Toge
Pages: 3-9
Published online on: 01 January 2002

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Article

Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas

Fabio Puglisi, Fabio Barbone, Gianluca Tell, Giuseppe Aprile, Barbara Pertoldi, Concetta Raiti, Mark R. Kelley, Giuseppe Damante, Alberto Sobrero, Carlo Alberto Beltrami, Carla Di Loreto
Pages: 11-17
Published online on: 01 January 2002

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Article

Different antigen unmasking techniques lead to significant differences in immunohistochemical staining of Ki-67 (Mib-1) in renal cell carcinomas

Martin Heuschmid, Georg Hofmockel, Barbara Dexler, Jobst Dammrich, Ioannis D. Bassukas
Pages: 19-22
Published online on: 01 January 2002

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Article

Prognostic significance of thymidine phosphorylase and p53 co-expression in esophageal squamous cell carcinoma

O. Makoto, A. Takeda, L. Ting-Leig, Okazumi Shinnichi, M. Hisahiro, F. Yutaka, N. Yoshihiro, S. Kobayashi, Y. Gunji, T. Suzuki, O. Takenori, S. Hideaki
Pages: 23-28
Published online on: 01 January 2002

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Article

5-FU improves p27-related poor prognosis in patients with Astler-Coller B2-C colorectal carcinoma

Minako Kobayashi, Taizo Shiraishi, Hitoshi Tonouchi, Chikao Miki, Masato Kusunoki
Pages: 29-33
Published online on: 01 January 2002

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Article

C-met and hepatocyte growth factor expression in combined hepatocellular and cholangiocarcinoma

Heike Varnholt, Yoshiki Asayama, Shin-ichi Aishima, Ken-ichi Taguchi, Keishi Sugimachi, Masazumi Tsuneyoshi
Pages: 35-41
Published online on: 01 January 2002

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Article

Telomerase activity during carcinogenesis in the bronchus

Masatoshi Kakihana, Naoyuki Yahata, Takashi Hirano, Hidetoshi Honda, Norihiko Ikeda, Norihiko Kawate, Chimori Konaka, Yoshiro Ebihara, Kazuma Ohyashiki, Harubumi Kato
Pages: 43-49
Published online on: 01 January 2002

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Article

Expression of CD44s and CD44 splice variants in human melanoma

Stella Maris Ranuncolo, Virginia Ladeda, Susana Gorostidy, Ana Morandi, Mirta Varela, Jose Lastiri, Dora Loria, Roxana Del Aguila, Elisa Bal de Kier Joffe, Guadalupe Pallotta, Lydia Puricelli
Pages: 51-56
Published online on: 01 January 2002

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Review

The tumor suppressor gene RIZ in cancer gene therapy (Review)

Richard Canote, Yong Du, Tobias Carling, Fang Tian, Zhaohui Peng, Shi Huang
Pages: 57-60
Published online on: 01 January 2002

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Article

Cellular calcium homeostasis changes in lymphoma-induction by ATP iron complex

Leopold J. Anghileri, Emilio Mayayo, Jose L. Domingo, Pierre Thouvenot
Pages: 61-64
Published online on: 01 January 2002

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Article

A novel strategy for remission induction and maintenance in cancer therapy

H. Tsuda, M. Sata, H. Ijuuin, T. Kumabe, M. Uchida, Y. Ogou, Y. Akagi, K. Shirouzu, H. Hara, Y. Nakashima
Pages: 65-68
Published online on: 01 January 2002

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Article

Prevention by long-term fermented miso of induction of colonic aberrant crypt foci by azoxymethane in F344 rats

M. Ohara, H. Lu, K. Shiraki, Y. Ishimura, T. Uesaka, O. Katoh, H. Watanabe
Pages: 69-73
Published online on: 01 January 2002

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Article

Up-regulation of vitamin D3 up-regulated protein 1 gene in response to 5-fluorouracil in colon carcinoma SW620

Yasuo Takahashi, Toshihito Nagata, Yukimoto Ishii, Masahito Ikarashi, Koichi Ishikawa, Satoshi Asai
Pages: 75-79
Published online on: 01 January 2002

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Article

Effect of wortmannin on the suppression of thermotolerance in tsAF8 cells

K. Shibuya, S. Kawasaki, M. Kuroda, M. Takemoto, J.-I. Asaumi, Y. Hiraki
Pages: 81-84
Published online on: 01 January 2002

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Article

Echocardiographic and pathological characteristics of cardiac metastasis in patients with lymphoma

Qingyi Meng, Hong Lai, Joao Lima, Wenjing Tong, Yuanyu Qian, Shenghan Lai
Pages: 85-88
Published online on: 01 January 2002

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Article

Paclitaxel and carboplatin in pretreated advanced gastric cancer: A phase II study

G. P. Stathopoulos, S. K. Rigatos, G. Fountzilas, A. Polyzos, J. G. Stathopoulos
Pages: 89-92
Published online on: 01 January 2002

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Article

Treatment of advanced colorectal adenocarcinoma with weekly high-dose l-leucovorin and 5-fluorouracil

Mutsumi Nozue, Naohide Isaka, Tsunehiko Maruyama, T. Kawamoto, K.-I. Seino, H. Tanagichi, K. Fukao
Pages: 93-96
Published online on: 01 January 2002

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Article

Prognostic factors of intrahepatic cholangiocarcinoma after surgical treatment

Hiroyuki Kinoshita, Hiroshi Tanimura, Kazuhisa Uchiyama, Masaji Tani, Hironobu Onishi, Hiroki Yamaue
Pages: 97-101
Published online on: 01 January 2002

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Article

Expression of Fas ligand and sFas ligand in human gastric adenocarcinomas

Sung-Chul Lim
Pages: 103-107
Published online on: 01 January 2002

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Article

Treatment and prognosis in colorectal cancer patients with bone metastasis

Mutsumi Nozue, Yukio Oshiro, Masanao Kurata, Ken-ichiro Seino, Naoto Koike, Toru Kawamoto, Hideki Taniguchi, Takeshi Todoroki, Katashi Fukao
Pages: 109-112
Published online on: 01 January 2002

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Article

Cell cycle arrest and the induction of apoptosis in pancreatic cancer cells exposed to adenosine triphosphate in vitro

Takayuki Yamada, Fumikazu Okajima, Mohammed Akbar, Hideaki Tomura, T. Narita, Tatsuya Yamada, Susumu Ohwada, Yasuo Morishita, Yoichi Kondo
Pages: 113-117
Published online on: 01 January 2002

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Article

Expression of vascular endothelial growth factor and basic fibroblast growth factor in small adenocarcinomas

Hiroyuki Ito, Fumihiro Oshita, Yoichi Kameda, Rie Suzuki, Mizuki Ikehara, Hiromasa Arai, Aki Mitsuda, Haruhiro Saito, Kouzo Yamada, Kazumasa Noda, Haruhiko Nakayama
Pages: 119-123
Published online on: 01 January 2002

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Article

Autocrine motility factor receptor gene expression and cell motility in lung cancer cell lines

I. Takanami, K. Takeuchi, H. Watanabe, T. Yanagawa, K. Takagishi
Pages: 125-128
Published online on: 01 January 2002

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Article

K-ras mutations and HPV infection in cervicitis and intraepithelial neoplasias of the cervix

Prokopis Prokopakis, George Sourvinos, Yvoni Koumantaki, Eugenios Koumantakis, Demetrios A. Spandidos
Pages: 129-133
Published online on: 01 January 2002

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Article

Differential TAG-72 epitope expression in breast cancer and lymph node metastases: a marker of a more aggressive phenotype

Annamaria Galietta, Claudia Pizzi, Guido Pettinato, Gennaro Limite, Alessandro Sgambato, Maria Lamberti, Raffaella Muraro, Cesare Formisano, Matilde Pensabene, Angelo Raffaele Bianco, Renato Mariani-Costantini, Alma Contegiacomo
Pages: 135-140
Published online on: 01 January 2002

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Article

Enhanced levels of deoxycytidine kinase and thymidine kinase 1 and 2 after pulsed low dose rate irradiation as an adaptive response to radiation

Natasja Castro Kreder, Chris van Bree, Godefridus J. Peters, Willem J. P. Loves, Jaap Haveman
Pages: 141-144
Published online on: 01 January 2002

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Article

Combined effects of lutenizing hormone-releasing hormone analogue with antiestrogen on rat mammary tumors

Hiroshi Matsumoto, Yukio Koibuchi, Jun Horiguchi, Yuichi Iino, Yasuo Morishita
Pages: 145-151
Published online on: 01 January 2002

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Article

Heterogeneity of apoptosis and proliferative activity within superficial spreading type early gastric cancer

Hirofumi Awata, Kazuo Hirose, Akio Yamaguchi
Pages: 153-158
Published online on: 01 January 2002

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Article

Elevated IL-8 levels in the drainage vein of resectable Dukes' C colorectal cancer indicate high risk for developing hepatic metastasis

Masashi Haraguchi, Ko Komuta, Arifumi Akashi, Sumihiro Matsuzaki, Junichiro Furui, Takashi Kanematsu
Pages: 159-165
Published online on: 01 January 2002

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Article

Accuracy of The Oncology Patients Information System in a regional cancer centre

Jonathan C. Yau, Arlene Chan, Tamina Eapen, Keith Oirourke, Libni Eapen
Pages: 167-169
Published online on: 01 January 2002

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Article

Prognostic significance of serum alkaline phosphatase in osteosarcoma of the extremity treated with neoadjuvant chemotherapy: Recent experience at Rizzoli Institute

Gaetano Bacci, Alessandra Longhi, Stefano Ferrari, Stefano Lari, Marco Manfrini, Davide Donati, Cristiana Forni, Michela Versari
Pages: 171-175
Published online on: 01 January 2002

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Article

Expression of Po66-CBP, a galectin-8, in different types of primary and secondary broncho-pulmonary tumors

S. Henno, F. Brichory, T. Langanay, B. Desrues, N. Bidon, P. Delaval, M.-P. Ramee, L. Dazord, S. Caulet-Maugendre
Pages: 177-180
Published online on: 01 January 2002

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Article

Improvement of the methylation specific PCR technical conditions for the detection of p16 promoter hypermethylation in small amounts of tumor DNA

X. Fan, M. M. Inda, T. Tunon, J. S. Castresana
Pages: 181-183
Published online on: 01 January 2002

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Article

Mammary tumors in splenectomized rats

G. Kossoy, H. Ben-Hur, O. Lifschitz, I. Zusman
Pages: 185-188
Published online on: 01 January 2002

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Article

Therapy of local recurrence of renal cell carcinoma

Christoph Wiesner, Gerhard Jakse, Detlef Rohde
Pages: 189-192
Published online on: 01 January 2002

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Article

The serum ferritin concentration is a significant prognostic indicator of survival in primary lung cancer

Nils Milman, Lars Moller Pedersen
Pages: 193-198
Published online on: 01 January 2002

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Article

Potentiated antitumor effects of butyrate and actinomycin D in melanoma model in mice

Adam Giermasz, Marcin Makowski, Dominika Nowis, Ahmad Jalili, Malgorzata Maj, Anna Dabrowska, Anna Czajka, Marek Jakobisiak, Jakub Golab
Pages: 199-203
Published online on: 01 January 2002

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Article

Retinoic acid inhibits fibronectin and laminin synthesis and cell migration of human pleural mesothelioma in vitro

Susanna Scarpa, Anna Giuffrida, Camilla Palumbo, Anna Coletti, Maria Grazia Cerrito, Fortunata Vasaturo, Paola Sinibaldi, Lucilla Simonelli, Antonio Procopio, Andrea Modesti
Pages: 205-209
Published online on: 01 January 2002

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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