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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2002 Volume 9 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Expression of p53 in preneoplastic and early neoplastic bronchial lesions

B. Martin, J.-M. Verdebout, C. Mascaux, M. Paesmans, G. Rouas, A. Verhest, V. Ninane, J.-P. Sculier
Pages: 223-229
Published online on: 01 March 2002

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Article

Primary colorectal tumour is not an accurate predictor of thymidylate synthase in lymph node metastasis

Sharon Marsh, Judith A. McKay, Stephanie Curran, G. I. Murray, James Cassidy, Howard L. McLeod
Pages: 231-234
Published online on: 01 March 2002

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Article

The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma

Jan Stoehlmacher, Sue A. Ingles, David J. Park, Wu Zhang, Heinz-Josef Lenz
Pages: 235-238
Published online on: 01 March 2002

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Article

Neovascularization in pancreatic ductal adenocarcinoma: Microvessel count analysis, comparison with non-cancerous regions and other types of carcinomas

Takanori Ueda, Tatsuya Oda, Taira Kinoshita, Masaru Konishi, Chigusa Nakahashi, Shinichirou Takahashi, Takahiro Hasebe, Katashi Fukao, Atsushi Ochiai
Pages: 239-245
Published online on: 01 March 2002

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Article

Expression of Fas ligand in patients with evident skull base involvement of nasopharyngeal carcinoma

Ming-Hsui Tsai, Kuan-Chih Chow, Tze-Yi Lin, Su-Peng Yeh, Chung-Tsen Hsueh, Kwan-Hwa Chi
Pages: 247-251
Published online on: 01 March 2002

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Article

Clinical significance of p53, MDM2 and bcl-2 expression in transitional cell carcinoma of the bladder

T. Uchida, S. Minei, J.-P. Gao, C. Wang, T. Satoh, S. Baba
Pages: 253-259
Published online on: 01 March 2002

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Article

Differential expression of heat shock protein 27 in normal oral mucosa, oral epithelial dysplasia and squamous cell carcinoma

Rosy Leonardi, Giuseppe Pannone, Gaetano Magro, Yasusei Kudo, Takashi Takata, Lorenzo Lo Muzio
Pages: 261-266
Published online on: 01 March 2002

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Review

Cancer vaccines: An update with special focus on ganglioside antigens (Review)

R. J. Bitton, M. D. Guthmann, M. R. Gabri, A. J.L. Carnero, D. F. Alonso, L. Fainboim, D. E. Gomez
Pages: 267-276
Published online on: 01 March 2002

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Article

Clinical evaluation of granisetron as an inhibitor of nausea and vomiting induced by oral anticancer drugs

Shinji Togo, Hirotoshi Akiyama, Shigeki Yamaguchi, Yasushi Ichikawa, Hideyuki Ike, Hiroshi Shimada
Pages: 277-282
Published online on: 01 March 2002

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Article

Treatment of patients with superficial bladder cancer by intravesical instillation of anticancer drugs plus oral chemotherapy following TUR-Bt: A randomized controlled trial

Hisashi Matsushima, Kazuki Kawabe, Makoto Fujime, Tadaichi Kitamura, Yukio Homma, Hiroichi Kishi, Takeshi Kawamura, Takashi Umeda, Yukihiko Ohishi, Masaru Murai, Tsuneo Kawai, Hideki Yoshida, Takashi Fukuda
Pages: 283-288
Published online on: 01 March 2002

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Article

Prognostic significance of a combination of thymidylate synthase and dihydropyrimidine dehydrogenase activities in grades 1 and 2 superficial bladder cancer

Yoichi Mizutani, Hiromi Wada, Osamu Yoshida, Masakazu Fukushima, Benjamin Bonavida, Akihiro Kawauchi, Tsuneharu Miki
Pages: 289-292
Published online on: 01 March 2002

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Article

Overexpression of p53 protein and point mutation of K-ras genes in primary carcinoma of the small intestine

Ken-ichi Nishiyama, Takashi Yao, Hirotoshi Yonemasu, Koji Yamaguchi, Masao Tanaka, Masazumi Tsuneyoshi
Pages: 293-300
Published online on: 01 March 2002

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Article

Prediction of cell kill kinetics of anticancer agents using the collagen gel droplet embedded-culture drug sensitivity test

Takeshi Mori, Masafumi Ohnishi, Megumi Komiyama, Arisa Tsutsui, Hiromitsu Yabushita, Hiroshi Okada
Pages: 301-305
Published online on: 01 March 2002

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Article

Using technetium-99m-tetrofosmin scan to predict chemotherapy response of malignant lymphomas, compared with P-glycoprotein and multidrug resistance related protein expression

J.-A. Liang, Y.-C. Shiau, S.-N. Yang, F.-J. Lin, C.-C. Lin, A. Kao, C.-C. Lee
Pages: 307-312
Published online on: 01 March 2002

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Article

Clinicopathologic characteristics of superficial spreading type squamous cell carcinoma of the esophagus

T. Nozoe, H. Saeki, T. Ohga, K. Sugimachi
Pages: 313-316
Published online on: 01 March 2002

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Article

Adenosquamous cell carcinoma arising from the papilla major

N. Ueno, T. Sano, T. Kanamaru, K.-I. Tanaka, T. Nishihara, Y. Idei, M. Yamamoto, T. Okuno, K. Kawaguchi
Pages: 317-320
Published online on: 01 March 2002

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Article

Comparison of 18F-fluoro-2-deoxyglucose positron emission tomography and gallium-67 citrate scintigraphy for detecting malignant lymphoma

Y.-Y. Shen, A. Kao, R.-F. Yen
Pages: 321-325
Published online on: 01 March 2002

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Article

Polymorphism analysis of CYP3A5 in myeloid leukemia

Ta-Chih Liu, Sheng-Fung Lin, Tyen-Po Chen, Jan-Gowth Chang
Pages: 327-329
Published online on: 01 March 2002

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Article

Chronological changes of causes of death and distant metastasis in hepatocellular carcinoma

Yoshinobu Itoh, Keiji Ohkubo, Hideto Iuchi, Kojiro Michitaka, Norio Horiike, Morikazu Onji
Pages: 331-335
Published online on: 01 March 2002

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Article

Suppression of tumor growth and pulmonary metastasis in murine osteosarcoma using gene therapy

Masashi Seto, Takashi Yamazaki, Jun Sonoda, Akihiko Matsumine, Yoshitaka Shinto, Atsumasa Uchida
Pages: 337-340
Published online on: 01 March 2002

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Article

Prognostic significance of heat shock protein 27 (HSP27) in patients with oral squamous cell carcinoma

Hiroshi Mese, Akira Sasaki, Shuko Nakayama, Norie Yoshioka, Yasuto Yoshihama, Koji Kishimoto, Tomohiro Matsumura
Pages: 341-344
Published online on: 01 March 2002

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Article

L-myc restriction fragment length polymorphism and histological pattern of invasion in lung adenocarcinoma

Hiroaki Suzuki, Katsushige Yamashiro
Pages: 345-347
Published online on: 01 March 2002

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Article

Intratumoral level of gonadotropin-releasing hormone in ovarian and endometrial cancers

Tatsuro Furui, Atsushi Imai, Teruhiko Tamaya
Pages: 349-352
Published online on: 01 March 2002

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Article

Uptake of indium-111-labeled human polyclonal immunoglobulin G in pancreatic cancer: In vivo and in vitro studies

Georgios Karanikas, Herbert Ulrich-Pur, Alexander Becherer, Karoline Wiesner, Robert Dudczak, Markus Raderer, Kurt Kletter
Pages: 353-357
Published online on: 01 March 2002

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Article

Changes in natural killer cell activity by external radiotherapy and/or brachytherapy

Hideya Yamazaki, Yasuo Yoshioka, Takehiro Inoue, Eiichi Tanaka, Miki Nishikubo, Tadayuki Sato, Takeshi Ishida, Hironobu Nakamura, Toshihiko Inoue
Pages: 359-363
Published online on: 01 March 2002

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Article

Thermochemotherapy of a human salivary adenocarcinoma cell line

Jun-ichi Asaumi, Yuzuru Higuchi, Hidenobu Matsuzaki, Jun Murakami, Shoji Kawasaki, Masahiro Kuroda, Koichi Shibuya, Hironobu Konouchi, Miki Hisatomi, Toru Wakasa, Kanji Kishi, Yoshio Hiraki
Pages: 365-369
Published online on: 01 March 2002

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Article

Leucine zipper structure of TSC-22 (TGF-β stimulated clone-22) markedly inhibits the anchorage-independent growth of salivary gland cancer cells

S. Hino, H. Kawamata, F. Omotehara, D. Uchida, N.-M. Begum, H. Yoshida, M. Sato, T. Fujimori
Pages: 371-374
Published online on: 01 March 2002

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Article

Predictive value of estrogen receptor status as assessed by ligand-binding assay in patients with early-stage breast cancer treated with breast conserving surgery and radiation therapy

H. Takei, J. Horiguchi, M. Maemura, Y. Koibuchi, T. Oyama, T. Yokoe, Y. Iino, Y. Morishita
Pages: 375-378
Published online on: 01 March 2002

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Article

Synergistic antitumour effect of a combination of toremifene and interferon-α on ZR-75-1 human breast cancer cells: Dependence on interferon-α subtype

J. H.J. Martin, A. Symonds
Pages: 379-382
Published online on: 01 March 2002

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Article

Q356R and S1512I are BRCA1 variants that may be associated with breast cancer in a Cypriot family

Andreas Hadjisavvas, Adamos Adamou, Catherine O'Dowd Phanis, Christopher M. Todd, Petros Kitsios, Kyriacos Kyriacou, Christina G. Christodoulou
Pages: 383-386
Published online on: 01 March 2002

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Article

Cyclic AMP-dependent secretion of Ca 19-9 by LS174T human colon carcinoma cells

Vincenzo Macchia, Maria Gargiulo, Daniela Terracciano, Angelina Di Carlo, Angela Mariano
Pages: 387-391
Published online on: 01 March 2002

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Article

Expression of the genes of methyl-binding domain proteins in human gliomas

Jurgen Schlegel, Suzan Guneysu, Hans-Dieter Mennel
Pages: 393-395
Published online on: 01 March 2002

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Article

Effects of growth factors on growth and radiation sensitivity of the human breast cancer cell line T-47D

Anne Beate Langeland Marthinsen, Anne Dybdahl Wanderas, Steinar Lundgren, Trond Strickert, Elisabeth Hundal, Bjorn Anton Graff
Pages: 397-403
Published online on: 01 March 2002

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Article

Intracystic breast carcinoma in a male: Unusual case presentation and literature review

Dipin Gupta, Michael H. Torosian
Pages: 405-407
Published online on: 01 March 2002

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Article

Expression and amplification of cyclin D1 in primary breast carcinomas: Relationship with histopathological types and clinico-pathological parameters

Rakesh Naidu, Norhanom Abdul Wahab, Man Mohan Yadav, Methil Kannan Kutty
Pages: 409-416
Published online on: 01 March 2002

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Article

Loss of heterozygosity and microsatellite instability in male breast cancer

Yunus A. Luqmani, Labiba L. Temmim, Manoj Mathew
Pages: 417-421
Published online on: 01 March 2002

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Article

Pentoxifylline inhibits perforin-dependent natural cytotoxicity in vitro

M. Lazarczyk, T. Grzela, G. Korczak-Kowalska, J. Niderla, M. Oldak, J. Jozwiak, P. Skopinski
Pages: 423-426
Published online on: 01 March 2002

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Article

IL-12 or IL-15, unlike IL-2, does not interact with histamine in augmenting cytotoxicity of splenocytes against melanoma cells and YAC-1 cells

Katarzyna Kozar, Rafal Kaminski, Adam Giermasz, Grzegorz Basak, Radoslaw Zagozdzon, Jolanta Rybczynska, Maria Wasik, Witold Lasek, Marek Jakobisiak, Jakub Golab
Pages: 427-431
Published online on: 01 March 2002

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Article

Rearrangement of p53 gene with overexpressed p53 protein in primary cervical cancer

Geeta Ram Sahu, Bijaya Kumar Nayak, Srinivas Patnaik, Tithi Parija, Bibhu Ranjan Das
Pages: 433-437
Published online on: 01 March 2002

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Article

Intensified ABVP chemotherapy for the primary treatment of Hodgkin's disease

Nelson Spector, Mario Alberto Costa, Jose Carlos Morais, Irene Biasoli, Cristiana Solza, Maria De Fatima Gaui, Carlos Gil Ferreira, Rodrigo Doyle Portugal, Monique Loureiro, Marcio Nucci, Wolmar Pulcheri
Pages: 439-442
Published online on: 01 March 2002

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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