|
1
|
Bray F, Laversanne M, Sung H, Ferlay J,
Siegel RL, Soerjomataram I and Jemal A: Global cancer statistics
2022: GLOBOCAN estimates of incidence and mortality worldwide for
36 cancers in 185 countries. CA Cancer J Clin. 74:229–263.
2024.PubMed/NCBI
|
|
2
|
Global cancer burden growing, amidst
mounting need for services. Saudi Med J. 45:326–327. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Li P, Dong J, Li Y, Yan J, Wang J, Cao S,
Cao W, Zhao X, Xue A, Xu Z and Yang L: The impact of ADAMTS14
genetic polymorphisms and its function on susceptibility to and
prognosis of gastric cancer in a Chinese Han population. Gastric
Cancer. 28:326–343. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Zhou X, Shen K, Cao S, Li P, Xiao J, Dong
J, Cheng Q, Hu L, Xu Z and Yang L: Polymorphism rs2327430 in TCF21
predicts the risk and prognosis of gastric cancer by affecting the
binding between TFAP2A and TCF21. Cancer Cell Int. 24:1592024.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Wang YQ, Li HZ, Gong WW, Chen YY, Zhu C,
Wang L, Zhong JM and Du LB: Cancer incidence and mortality in
Zhejiang Province, Southeast China, 2016: A population-based study.
Chin Med J (Engl). 134:1959–1966. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Han SH, Jang S, Kim Y, Tan K, Wilkinson
MF, Jeong H and Choe J: Genetic variants reshape the m6A
epitranscriptome and drive transcriptomic reprogramming in
colorectal cancer. Sci Rep. 15:393842025. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Hua J, Qian Y, Lu Y, Zhang Q, Que H, Zeng
T, Li Q, Deng J and Xie J: Cross-tissue transcriptome-wide
association studies identify genetic susceptibility genes for
prostate cancer. BMC Cancer. 25:17082025. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Chidambaram D, Subashini V, Nanthanalaxmi
M, Saranya I and Selvamurugan N: Regulation of matrix
metalloproteinase-13 in cancer: Signaling pathways and non-coding
RNAs in tumor progression and therapeutic targeting. World J Clin
Oncol. 16:1059962025. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Niland S, Riscanevo AX and Eble JA: Matrix
metalloproteinases shape the tumor microenvironment in cancer
progression. Int J Mol Sci. 23:1462021. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Piperigkou Z, Mangani S, Kremmydas S,
Koletsis NE and Karamanos NK: A guide to the types, structures, and
multifaceted functions of matrix metalloproteinases in cancer. FEBS
J. Oct 29–2025.(Epub ahead of print). View Article : Google Scholar
|
|
11
|
Mustafa S, Koran S and AlOmair L: Insights
into the role of matrix metalloproteinases in cancer and its
various therapeutic aspects: A review. Front Mol Biosci.
9:8960992022. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gonzalez-Avila G, Sommer B,
García-Hernández AA and Ramos C: Matrix metalloproteinases' role in
tumor microenvironment. Adv Exp Med Biol. 1245:97–131. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Xu DM, Chen LX, Xue T, Zhuang XY, Wei LC,
Han H and Mo M: Decoding the impact of MMP1+ malignant subsets on
tumor-immune interactions: Insights from single-cell and spatial
transcriptomics. Cell Death Discov. 11:2442025. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Aleman JD, Young CD, Karam SD and Wang XJ:
Revisiting laminin and extracellular matrix remodeling in
metastatic squamous cell carcinoma: What have we learned after more
than four decades of research? Mol Carcinog. 62:5–23. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Rong S, Li C, Li S, Wu S and Sun F:
Genetically modified adipose-derived stem cells with matrix
metalloproteinase 3 promote scarless cutaneous repair. Dermatol
Ther. 33:e141122020. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Niwa H, Kanno Y, Shu E and Seishima M:
Decrease in matrix metalloproteinase-3 activity in systemic
sclerosis fibroblasts causes α2-antiplasmin and extracellular
matrix deposition, and contributes to fibrosis development. Mol Med
Rep. 22:3001–3007. 2020.PubMed/NCBI
|
|
17
|
Boukpessi T, Menashi S, Camoin L, Tencate
JM, Goldberg M and Chaussain-Miller C: The effect of stromelysin-1
(MMP-3) on non-collagenous extracellular matrix proteins of
demineralized dentin and the adhesive properties of restorative
resins. Biomaterials. 29:4367–4373. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Juurikka K, Butler GS, Salo T, Nyberg P
and Åström P: The role of MMP8 in cancer: A systematic review. Int
J Mol Sci. 20:45062019. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Brassart-Pasco S, Brézillon S, Brassart B,
Ramont L, Oudart JB and Monboisse JC: Tumor microenvironment:
Extracellular matrix alterations influence tumor progression. Front
Oncol. 10:3972020. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kourie HR, Zouein J, Succar B,
Mardirossian A, Ahmadieh N, Chouery E, Mehawej C, Jalkh N, Kattan J
and Nemr E: Genetic polymorphisms involved in bladder cancer: A
global review. Oncol Rev. 17:106032023. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Chen H, Xu X, Hua C, Zhang H, Jian J, Ge
T, Xie J and Yu Z: Polymorphisms of matrix metalloproteinases
affect the susceptibility of esophageal cancer: Evidence from 20412
subjects, systematic review and updated meta-analysis. Medicine
(Baltimore). 100:e272292021. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chen CC, Pei JS, Tzeng HE, Hsu PC, Hsia
TC, Wang YC, Su MY, Shih HY, Chang WS, Bau DT and Tsai CW: The
genetic role of matrix metalloproteinase-12 in determining
childhood acute lymphocytic leukemia risk. Anticancer Res.
45:4231–4241. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Li X, Liu C, Ran R, Liu G, Yang Y, Zhao W,
Xie X and Li J: Matrix metalloproteinase family gene polymorphisms
and lung cancer susceptibility: An updated meta-analysis. J Thorac
Dis. 12:349–362. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Khoury MJ, Bertram L, Boffetta P,
Butterworth AS, Chanock SJ, Dolan SM, Fortier I, Garcia-Closas M,
Gwinn M, Higgins JP, et al: Genome-wide association studies, field
synopses, and the development of the knowledge base on genetic
variation and human diseases. Am J Epidemiol. 170:269–279. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Sagoo GS, Little J and Higgins JP:
Systematic reviews of genetic association studies. Human genome
epidemiology network. PLoS Med. 6:e282009. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Page MJ, McKenzie JE, Bossuyt PM, Boutron
I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan
SE, et al: The PRISMA 2020 statement: An updated guideline for
reporting systematic reviews. BMJ. 372:n712021. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Egger M, Davey Smith G, Schneider M and
Minder C: Bias in meta-analysis detected by a simple, graphical
test. BMJ. 315:629–634. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Begg CB and Mazumdar M: Operating
characteristics of a rank correlation test for publication bias.
Biometrics. 50:1088–1101. 1994. View
Article : Google Scholar : PubMed/NCBI
|
|
29
|
Zhang WP, Yang C, Xu LJ, Wang W, Song L
and He XF: Individual and combined effects of GSTM1, GSTT1, and
GSTP1 polymorphisms on lung cancer risk: A meta-analysis and
re-analysis of systematic meta-analyses. Medicine (Baltimore).
100:e261042021. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Cargnin S, Galli U, Lee KS, Shin JI and
Terrazzino S: Gene polymorphisms and risk of acute renal graft
rejection: A field synopsis of meta-analyses and genome-wide
association studies. Transplant Rev (Orlando). 34:1005482020.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Ioannidis JP, Boffetta P, Little J,
O'Brien TR, Uitterlinden AG, Vineis P, Balding DJ, Chokkalingam A,
Dolan SM, Flanders WD, et al: Assessment of cumulative evidence on
genetic associations: Interim guidelines. Int J Epidemiol.
37:120–132. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zeng J and Li G: T Fmapper: A tool for
searching putative factors regulating gene expression using
ChIP-seq data. Int J Biol Sci. 14:1724–1731. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Ward LD and Kellis M: HaploReg v4:
Systematic mining of putative causal variants, cell types,
regulators and target genes for human complex traits and disease.
Nucleic Acids Res. 44(D1): D877–D881. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Grundberg E, Small KS, Hedman ÅK, Nica AC,
Buil A, Keildson S, Bell JT, Yang TP, Meduri E, Barrett A, et al:
Mapping cis- and trans-regulatory effects across multiple tissues
in twins. Nat Genet. 44:1084–1089. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
GTEx Consortium: The GTEx Consortium atlas
of genetic regulatory effects across human tissues. Science.
369:1318–1330. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
1000 Genomes Project Consortium, . Auton
A, Brooks LD, Durbin RM, Garrison EP, Kang HM, Korbel JO, Marchini
JL, McCarthy S, McVean GA and Abecasis GR: A global reference for
human genetic variation. Nature. 526:68–74. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Machiela MJ and Chanock SJ: LDlink: A
web-based application for exploring population-specific haplotype
structure and linking correlated alleles of possible functional
variants. Bioinformatics. 31:3555–3557. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Li M, Yan T, Cai Y, Wei Y and Xie Q:
Expression of matrix metalloproteinases and their association with
clinical characteristics of solid tumors. Gene. 850:1469272023.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Rutter JL, Mitchell TI, Butticè G, Meyers
J, Gusella JF, Ozelius LJ and Brinckerhoff CE: A single nucleotide
polymorphism in the matrix metalloproteinase-1 promoter creates an
Ets binding site and augments transcription. Cancer Res.
58:5321–5325. 1998.PubMed/NCBI
|
|
40
|
Wu MH, Yueh TC, Chang WS, Tsai CW, Fu CK,
Yang MD, Yu CC and Bau DT: Contribution of matrix
metalloproteinase-1 genotypes to colorectal cancer in Taiwan.
Cancer Genomics Proteomics. 18:245–251. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Liao CH, Tsai CW, Chang WS, Wang ZH, Gong
CL, Wu HC, Wang BR, Hsu SW, Huang WC, Shen TC and Bau DT:
Association of matrix metalloproteinase-1 genotypes with bladder
cancer risk. In Vivo. 35:2535–2540. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Ito K, Kitajima Y, Kai K, Matsufuji S,
Yamada K, Egawa N, Kitagawa H, Okuyama K, Tanaka T and Noshiro H:
Matrix metalloproteinase-1 expression is regulated by
HIF-1-dependent and epigenetic mechanisms and serves a
tumor-suppressive role in gastric cancer progression. Int J Oncol.
59:1022021. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
McCready J, Broaddus WC, Sykes V and
Fillmore HL: Association of a single nucleotide polymorphism in the
matrix metalloproteinase-1 promoter with glioblastoma. Int J
Cancer. 117:781–785. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Aitchison EE, Dimesa AM and Shoari A:
Matrix metalloproteinases in glioma: Drivers of invasion and
therapeutic targets. BioTech (Basel). 14:282025. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Jiang J, Wu Q, Rajasekaran S and Wu R:
MMP3 at the crossroads: Linking molecular pathways to disease
diagnosis and therapy. Pharmacol Res. 216:1077502025. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Boaru DL, De Leon-Oliva D, De
Castro-Martinez P, Garcia-Montero C, Fraile-Martinez O,
García-González B, Pérez-González I, Alhaddadin MNM,
Barrena-Blázquez S, Lopez-Gonzalez L, et al: Extracellular matrix
dysregulation in aging, calcification, and cancer diseases:
Insights into cellular senescence, inflammation, and novel
therapeutic strategies. Int J Biol Sci. 21:6808–6881. 2025.
View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Souslova V, Townsend PA, Mann J, van der
Loos CM, Motterle A, D'Acquisto F, Mann DA and Ye S:
Allele-specific regulation of matrix metalloproteinase-3 gene by
transcription factor NFkappaB. PLoS One. 5:e99022010. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Kader AK, Shao L, Dinney CP, Schabath MB,
Wang Y, Liu J, Gu J, Grossman HB and Wu X: Matrix metalloproteinase
polymorphisms and bladder cancer risk. Cancer Res. 66:11644–11648.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Hirata H, Okayama N, Naito K, Inoue R,
Yoshihiro S, Matsuyama H, Suehiro Y, Hamanaka Y and Hinoda Y:
Association of a haplotype of matrix metalloproteinase (MMP)-1 and
MMP-3 polymorphisms with renal cell carcinoma. Carcinogenesis.
25:2379–2384. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Baliu-Piqué M, Pandiella A and Ocana A:
Breast cancer heterogeneity and response to novel therapeutics.
Cancers (Basel). 12:32712020. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Pallavi R, Soni BL, Jha GK, Sanyal S,
Fatima A and Kaliki S: Tumor heterogeneity in retinoblastoma: A
literature review. Cancer Metastasis Rev. 44:462025. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Manolio TA, Collins FS, Cox NJ, Goldstein
DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR,
Chakravarti A, et al: Finding the missing heritability of complex
diseases. Nature. 461:747–753. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Kraft P and Hunter DJ: Genetic risk
prediction-are we there yet? N Engl J Med. 360:1701–1703. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Chatterjee N, Shi J and García-Closas M:
Developing and evaluating polygenic risk prediction models for
stratified disease prevention. Nat Rev Genet. 17:392–406. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Torkamani A, Wineinger NE and Topol EJ:
The personal and clinical utility of polygenic risk scores. Nat Rev
Genet. 19:581–590. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Popejoy AB and Fullerton SM: Genomics is
failing on diversity. Nature. 538:161–164. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Peng B, Cao L, Wang W, Xian L, Jiang D,
Zhao J, Zhang Z, Wang X and Yu L: Polymorphisms in the promoter
regions of matrix metalloproteinases 1 and 3 and cancer risk: a
meta-analysis of 50 case-control studies. Mutagenesis. 25:41–48.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Peng Q and Xu Y: Association between
promoter polymorphisms of matrix metalloproteinase-1 and risk of
gastric cancer. Onco Targets Ther. 8:2519–2526. 2015.PubMed/NCBI
|
|
59
|
Feng J, Chen Y, Hua W, Sun X, Chen Y, Liu
Y, Fan J, Zhao Y, Zhao L, Xu X and Yang X: The MMP-8 rs11225395
promoter polymorphism increases cancer risk of non-Asian
populations: Evidence from a meta-analysis. Biomolecules.
9:5702019. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
McColgan P and Sharma P: Polymorphisms of
matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung,
breast and colorectal cancer in over 30,000 subjects. Int J Cancer.
125:1473–1478. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Fiotti N, Mearelli F, Di Girolamo FG,
Castello LM, Nunnari A, Di Somma S, Lupia E, Colonetti E, Muiesan
ML, Montrucchio G, et al: Genetic variants of matrix
metalloproteinase and sepsis: The need speed study. Biomolecules.
12:2792022. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Zhang H, Luo YB, Wu W, Zhang L, Wang Z,
Dai Z, Feng S, Cao H, Cheng Q and Liu Z: The molecular feature of
macrophages in tumor immune microenvironment of glioma patients.
Comput Struct Biotechnol J. 19:4603–4618. 2021. View Article : Google Scholar : PubMed/NCBI
|
