[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Lee,Geum-Hwa; Kim,Do-Sung; Chung,Myung Ja; Chae,Soo-Wan; Kim,Hyung-Ryong; Chae,Han-Jung

doi:10.3892/ol.2026.15867

November-2026 Volume 32 Issue 5

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November-2026 Volume 32 Issue 5

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Authors:
- Geum-Hwa Lee
- Do-Sung Kim
- Myung Ja Chung
- Soo-Wan Chae
- Hyung-Ryong Kim
- Han-Jung Chae
View Affiliations / Copyright

Affiliations: Department of Pharmacology and Cardiovascular Research Institute, Chonbuk National University, Jeonju 560-182, Republic of Korea, Department of Pathology, School of Medicine, Chonbuk National University, Jeonju 560-182, Republic of Korea, Department of Dental Pharmacology, School of Dentistry, Wonkwang University, Iksan 570-749, Republic of Korea

Copyright: © Lee et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 512
|
Published online on: September 16, 2026

https://doi.org/10.3892/ol.2026.15867
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Oncol Lett 2: [Related article:] 831–838, 2011; DOI: 10.3892/ol.2011.353

Subsequently to the publication of the above article, an interested reader drew to the authors' attention that, concerning the cellular invasion assay data shown in Fig. 3A on p. 835, data shown in the ‘LOCL-1 siRNA’ panel were strikingly similar to data that had already appeared in an article written by the same research group, which was published in the journal Oncogene.

Figure 3.

Endogenous LOXL-1 plays a significant role in the extracellular accumulation of lactate and the expression of its transporter, MCT1/2, in in vitro cancer metastasis. (A) HT1080 cells were transfected with non-specific or LOXL-1-specific siRNA and the expression of LOXL-1 was confirmed (upper panel). The invasion analysis was performed as in Fig. 2A. The 0.1% crystal violet staining cells in the lower chamber are shown (A, lower panel). (B) The number was determined by counting cells in the lower wells (C). The width of the injury line was quantified at the indicated culturing periods, 0, 6, 12, 18 or 24 h. (D) Lactate in the medium was measured when non-specific and LOXL-1 siRNA-transfected cells were cultured for the indicated periods (12, 24, 36 or 48 h) (E and F) Western blotting was performed with anti-MCT1/2, MMP2/9, LOXL-1 or β-actin antibodies. (G) Zymography was performed for MMP2/9 activity. *P<0.05, significantly different from the non-specific siRNA-transfected condition. NSsi, non-specific siRNA.

After re-examining their original data, the authors were able to confirm that Fig. 3 had been assembled incorrectly in the above paper. A revised version of Fig. 3, now showing the correct data for the ‘LOCL-1 siRNA’ panel in Fig. 3A, is shown on the next page. Note that the revision made to this figure has not led to any significant changes in either the results or the conclusions reported in this paper. The authors are grateful to the Editor of Oncology Letters for allowing them this opportunity to publish a Corrigendum, and all the authors agree with its publication; furthermore, they apologize to the readership for any inconvenience caused.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

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