1
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar
|
2
|
Lou C, Du Z, Yang B, Gao Y, Wang Y and
Fang S: Aberrant DNA methylation profile of hepatocellular
carcinoma and surgically resected margin. Cancer Sci. 100:996–1004.
2009. View Article : Google Scholar : PubMed/NCBI
|
3
|
Matsuda Y, Ichida T, Matsuzawa J, Sugimura
K and Asakura H: p16(INK4) is inactivated by extensive CpG
methylation in human hepatocellular carcinoma. Gastroenterology.
116:394–400. 1999. View Article : Google Scholar : PubMed/NCBI
|
4
|
Zhang YJ, Ahsan H, Chen Y, Lunn RM, Wang
LY, Chen SY, Lee PH, Chen CJ and Santella RM: High frequency of
promoter hypermethylation of RASSF1A and p16 and its relationship
to aflatoxin B1-DNA adduct levels in human hepatocellular
carcinoma. Mol Carcinog. 35:85–92. 2002. View Article : Google Scholar : PubMed/NCBI
|
5
|
Tchou JC, Lin X, Freije D, Isaacs WB,
Brooks JD, Rashid A, De Marzo AM, Kanai Y, Hirohashi S and Nelson
WG: GSTP1 CpG island DNA hypermethylation in hepatocellular
carcinomas. Int J Oncol. 16:663–676. 2000.PubMed/NCBI
|
6
|
Calvisi DF, Ladu S, Gorden A, Farina M,
Lee JS, Conner EA, Schroeder I, Factor VM and Thorgeirsson SS:
Mechanistic and prognostic significance of aberrant methylation in
the molecular pathogenesis of human hepatocellular carcinoma. J
Clin Invest. 117:2713–2722. 2007. View
Article : Google Scholar : PubMed/NCBI
|
7
|
Nishida N, Kudo M, Nagasaka T, Ikai I and
Goel A: Characteristic patterns of altered DNA methylation predict
emergence of human hepatocellular carcinoma. Hepatology.
56:994–1003. 2012. View Article : Google Scholar : PubMed/NCBI
|
8
|
Benjamini Y and Hochberg Y: Controlling
the false discovery rate: A practical and powerful approach to
multiple testing. J R Stat Soc Series B Stat Methodol. 57:289–300.
1995.
|
9
|
Zen K, Yasui K, Nakajima T, Zen Y, Zen K,
Gen Y, Mitsuyoshi H, Minami M, Mitsufuji S, Tanaka S, et al: ERK5
is a target for gene amplification at 17p11 and promotes cell
growth in hepatocellular carcinoma by regulating mitotic entry.
Genes Chromosomes Cancer. 48:109–120. 2009. View Article : Google Scholar
|
10
|
Dohi O, Yasui K, Gen Y, Takada H, Endo M,
Tsuji K, Konishi C, Yamada N, Mitsuyoshi H, Yagi N, et al:
Epigenetic silencing of miR-335 and its host gene MEST in
hepatocellular carcinoma. Int J Oncol. 42:411–418. 2013.
|
11
|
Kanehisa M and Goto S: KEGG: Kyoto
encyclopedia of genes and genomes. Nucleic Acids Res. 28:27–30.
2000. View Article : Google Scholar
|
12
|
Huang W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2009. View Article : Google Scholar
|
13
|
Huang W, Sherman BT and Lempicki RA:
Bioinformatics enrichment tools: Paths toward the comprehensive
functional analysis of large gene lists. Nucleic Acids Res.
37:1–13. 2009. View Article : Google Scholar :
|
14
|
Nishida N, Nagasaka T, Nishimura T, Ikai
I, Boland CR and Goel A: Aberrant methylation of multiple tumor
suppressor genes in aging liver, chronic hepatitis, and
hepatocellular carcinoma. Hepatology. 47:908–918. 2008. View Article : Google Scholar
|
15
|
Edamoto Y, Hara A, Biernat W, Terracciano
L, Cathomas G, Riehle HM, Matsuda M, Fujii H, Scoazec JY and Ohgaki
H: Alterations of RB1, p53 and Wnt pathways in hepatocellular
carcinomas associated with hepatitis C, hepatitis B and alcoholic
liver cirrhosis. Int J Cancer. 106:334–341. 2003. View Article : Google Scholar : PubMed/NCBI
|
16
|
Sugi T, Oyama T, Muto T, Nakanishi S,
Morikawa K and Jingami H: Crystal structures of autoinhibitory PDZ
domain of Tamalin: Implications for metabotropic glutamate receptor
trafficking regulation. EMBO J. 26:2192–2205. 2007. View Article : Google Scholar : PubMed/NCBI
|
17
|
Venkataraman A, Nevrivy DJ, Filtz TM and
Leid M: Grp1-associated scaffold protein (GRASP) is a regulator of
the ADP ribosylation factor 6 (Arf6)-dependent membrane trafficking
pathway. Cell Biol Int. 36:1115–1128. 2012. View Article : Google Scholar : PubMed/NCBI
|
18
|
Tao R, Li J, Xin J, Wu J, Guo J, Zhang L,
Jiang L, Zhang W, Yang Z and Li L: Methylation profile of single
hepatocytes derived from hepatitis B virus-related hepatocellular
carcinoma. PLoS One. 6:e198622011. View Article : Google Scholar : PubMed/NCBI
|
19
|
Fukai K, Yokosuka O, Chiba T, Hirasawa Y,
Tada M, Imazeki F, Kataoka H and Saisho H: Hepatocyte growth factor
activator inhibitor 2/placental bikunin (HAI-2/PB) gene is
frequently hypermethylated in human hepatocellular carcinoma.
Cancer Res. 63:8674–8679. 2003.PubMed/NCBI
|
20
|
Tung EK, Wong CM, Yau TO, Lee JM, Ching YP
and Ng IO: HAI-2 is epigenetically downregulated in human
hepatocellular carcinoma, and its Kunitz domain type 1 is critical
for anti-invasive functions. Int J Cancer. 124:1811–1819. 2009.
View Article : Google Scholar
|
21
|
Dong W, Chen X, Xie J, Sun P and Wu Y:
Epigenetic inactivation and tumor suppressor activity of
HAI-2/SPINT2 in gastric cancer. Int J Cancer. 127:1526–1534. 2010.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Nakamura K, Abarzua F, Kodama J, Hongo A,
Nasu Y, Kumon H and Hiramatsu Y: Expression of hepatocyte growth
factor activator inhibitors (HAI-1 and HAI-2) in ovarian cancer.
Int J Oncol. 34:345–353. 2009.PubMed/NCBI
|
23
|
Nakamura K, Abarzua F, Hongo A, Kodama J,
Nasu Y, Kumon H and Hiramatsu Y: Hepatocyte growth factor activator
inhibitor-2 (HAI-2) is a favorable prognosis marker and inhibits
cell growth through the apoptotic pathway in cervical cancer. Ann
Oncol. 20:63–70. 2009. View Article : Google Scholar
|
24
|
Morris MR, Gentle D, Abdulrahman M, Maina
EN, Gupta K, Banks RE, Wiesener MS, Kishida T, Yao M, Teh B, et al:
Tumor suppressor activity and epigenetic inactivation of hepatocyte
growth factor activator inhibitor type 2/SPINT2 in papillary and
clear cell renal cell carcinoma. Cancer Res. 65:4598–4606. 2005.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Yue D, Fan Q, Chen X, Li F, Wang L, Huang
L, Dong W, Chen X, Zhang Z, Liu J, et al: Epigenetic inactivation
of SPINT2 is associated with tumor suppressive function in
esophageal squamous cell carcinoma. Exp Cell Res. 322:149–158.
2014. View Article : Google Scholar
|
26
|
Lefrançois-Martinez AM, Bertherat J, Val
P, Tournaire C, Gallo-Payet N, Hyndman D, Veyssière G, Bertagna X,
Jean C and Martinez A: Decreased expression of cyclic adenosine
mono-phosphate-regulated aldose reductase (AKR1B1) is associated
with malignancy in human sporadic adrenocortical tumors. J Clin
Endocrinol Metab. 89:3010–3019. 2004. View Article : Google Scholar
|
27
|
Wellen KE, Fucho R, Gregor MF, Furuhashi
M, Morgan C, Lindstad T, Vaillancourt E, Gorgun CZ, Saatcioglu F
and Hotamisligil GS: Coordinated regulation of nutrient and
inflammatory responses by STAMP2 is essential for metabolic
homeostasis. Cell. 129:537–548. 2007. View Article : Google Scholar : PubMed/NCBI
|
28
|
Korkmaz CG, Korkmaz KS, Kurys P, Elbi C,
Wang L, Klokk TI, Hammarstrom C, Troen G, Svindland A, Hager GL, et
al: Molecular cloning and characterization of STAMP2, an
androgen-regulated six transmembrane protein that is overexpressed
in prostate cancer. Oncogene. 24:4934–4945. 2005. View Article : Google Scholar : PubMed/NCBI
|
29
|
Tamura T and Chiba J: STEAP4 regulates
focal adhesion kinase activation and CpG motifs within STEAP4
promoter region are frequently methylated in DU145, human
androgen-independent prostate cancer cells. Int J Mol Med.
24:599–604. 2009. View Article : Google Scholar : PubMed/NCBI
|
30
|
Reinert T, Borre M, Christiansen A,
Hermann GG, Ørntoft TF and Dyrskjøt L: Diagnosis of bladder cancer
recurrence based on urinary levels of EOMES, HOXA9, POU4F2, TWIST1,
VIM, and ZNF154 hypermethylation. PLoS One. 7:e462972012.
View Article : Google Scholar : PubMed/NCBI
|
31
|
Sánchez-Vega F, Gotea V, Petrykowska HM,
Margolin G, Krivak TC, DeLoia JA, Bell DW and Elnitski L: Recurrent
patterns of DNA methylation in the ZNF154, CASP8, and VHL promoters
across a wide spectrum of human solid epithelial tumors and cancer
cell lines. Epigenetics. 8:1355–1372. 2013. View Article : Google Scholar : PubMed/NCBI
|
32
|
Saffin JM, Venoux M, Prigent C, Espeut J,
Poulat F, Giorgi D, Abrieu A and Rouquier S: ASAP, a human
microtubule-associated protein required for bipolar spindle
assembly and cytokinesis. Proc Natl Acad Sci USA. 102:11302–11307.
2005. View Article : Google Scholar : PubMed/NCBI
|
33
|
Rouquier S, Pillaire MJ, Cazaux C and
Giorgi D: Expression of the microtubule-associated protein
MAP9/ASAP and its partners AURKA and PLK1 in colorectal and breast
cancers. Dis Markers. 2014:7981702014. View Article : Google Scholar : PubMed/NCBI
|
34
|
Castleman VH, Romio L, Chodhari R, Hirst
RA, de Castro SC, Parker KA, Ybot-Gonzalez P, Emes RD, Wilson SW,
Wallis C, et al: Mutations in radial spoke head protein genes RSPH9
and RSPH4A cause primary ciliary dyskinesia with
central-micro-tubular-pair abnormalities. Am J Hum Genet.
84:197–209. 2009. View Article : Google Scholar : PubMed/NCBI
|