Hypothesis: more mutations to cure cancer?

  • Authors:
    • F Eisinger
    • H Sobol
    • D Birnbaum
  • View Affiliations

  • Published online on: November 1, 1999     https://doi.org/10.3892/or.6.6.1189
  • Pages: 1189-1279
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Abstract

Cancer results from the accumulation of selected mutations. We propose here that some combinations of mutations may be counterselected. To illustrate this, we show an analysis of allelotyping in human breast tumors in which we demonstrate that specific associations of genetic events are statistically under-represented. This emerging concept could be used in a new therapeutical approach of cancer.

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Nov-Dec 1999
Volume 6 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Eisinger F, Sobol H and Birnbaum D: Hypothesis: more mutations to cure cancer?. Oncol Rep 6: 1189-1279, 1999
APA
Eisinger, F., Sobol, H., & Birnbaum, D. (1999). Hypothesis: more mutations to cure cancer?. Oncology Reports, 6, 1189-1279. https://doi.org/10.3892/or.6.6.1189
MLA
Eisinger, F., Sobol, H., Birnbaum, D."Hypothesis: more mutations to cure cancer?". Oncology Reports 6.6 (1999): 1189-1279.
Chicago
Eisinger, F., Sobol, H., Birnbaum, D."Hypothesis: more mutations to cure cancer?". Oncology Reports 6, no. 6 (1999): 1189-1279. https://doi.org/10.3892/or.6.6.1189