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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">IJMM</journal-id>
<journal-title-group>
<journal-title>International Journal of Molecular Medicine</journal-title></journal-title-group>
<issn pub-type="ppub">1107-3756</issn>
<issn pub-type="epub">1791-244X</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name></publisher></journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/ijmm.2022.5100</article-id>
<article-id pub-id-type="publisher-id">ijmm-49-04-05100</article-id>
<article-categories>
<subj-group>
<subject>Corrigendum</subject></subj-group></article-categories>
<title-group>
<article-title>miR-29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC-1&#x003B1; signaling: Implications for age-related hearing loss</article-title></title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Xue</surname><given-names>Tao</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Wei</surname><given-names>Li</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Zha</surname><given-names>Ding-Jun</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Qiu</surname><given-names>Jian-Hua</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Chen</surname><given-names>Fu-Quan</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Qiao</surname><given-names>Li</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Qiu</surname><given-names>Yang</given-names></name></contrib></contrib-group>
<pub-date pub-type="ppub">
<month>04</month>
<year>2022</year></pub-date>
<pub-date pub-type="epub">
<day>07</day>
<month>02</month>
<year>2022</year></pub-date>
<volume>49</volume>
<issue>4</issue>
<elocation-id>45</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x000A9; Xue et al.</copyright-statement>
<copyright-year>2022</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/">Creative Commons Attribution-NonCommercial-NoDerivs License</ext-link>, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.</license-p></license></permissions></article-meta></front>
<body>
<p>Int J Mol Med 38: <related-article id="RA1" related-article-type="corrected-article" vol="38" page="1387" ext-link-type="doi" xlink:href="10.3892/ijmm.2016.2735">1387-1394</related-article>, 2018; DOI: 10.3892/ijmm.2016.2735</p>
<p>Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that the bar charts shown in <xref rid="f4-ijmm-49-04-05100" ref-type="fig">Fig. 4A and B</xref>, which were intending to have shown the RT-qPCR and western blot analyses of SIRT1 and PGC-1&#x003B1; in HEI-OC1 cells, respectively, under different experimental conditions were apparently identical. Similarly, in <xref rid="f5-ijmm-49-04-05100" ref-type="fig">Fig. 5</xref>, the histograms shown in <xref rid="f5-ijmm-49-04-05100" ref-type="fig">Fig. 5C and D</xref>, which were intending to have shown the RT-qPCR and western blot analyses, respectively, of SIRT1 and PGC-1&#x003B1; in HEI-OC1 cells subjected to different treatments were also apparently identical. The authors have re-examined their data, and realize that the data properly belonging to the protein expression levels had been wrongly used to show the mRNA levels, and therefore <xref rid="f4-ijmm-49-04-05100" ref-type="fig">Figs. 4A</xref> and <xref rid="f5-ijmm-49-04-05100" ref-type="fig">5C</xref> were presented incorrectly in these figures.</p>
<p>The revised versions of <xref rid="f4-ijmm-49-04-05100" ref-type="fig">Figs. 4</xref> and <xref rid="f5-ijmm-49-04-05100" ref-type="fig">5</xref>, containing the correct data for the RT-qPCR experiments in <xref rid="f4-ijmm-49-04-05100" ref-type="fig">Figs. 4A</xref> and <xref rid="f5-ijmm-49-04-05100" ref-type="fig">5C</xref>, are shown on the next page. These errors did not affect the major conclusions reported in the paper. All the authors have agreed to this corrigendum, and thank the Editor of <italic>International Journal of Molecular Medicine</italic> for allowing them the opportunity to publish this. The authors regret these errors went unnoticed during the compilation of the figures in question, and apologize to the readership for any confusion that this may have caused.</p>
<fig id="f4-ijmm-49-04-05100" position="float">
<label>Figure 4</label>
<caption>
<p>miR-29b regulates the expression of sirtuin 1 (SIRT1) and proliferator-activated receptor-gamma coactivator 1&#x003B1; (PGC-1&#x003B1;) in HEI-OC1 cells. (A) RT-qPCR analysis of SIRT1 and PGC-1&#x003B1; in HEI-OC1 cells subjected to different treatments. <sup>#</sup>p&lt;0.05 compared to the control group; <sup>&#x0002A;</sup>p&lt;0.05 compared to the H<sub>2</sub>O<sub>2</sub> group. (B) Protein expression of SIRT1 and PGC-1&#x003B1; determined by western blot analysis in HEI-OC1 cells subjected to different treatments. <sup>#</sup>p&lt;0.05 compared to the control group; <sup>&#x0002A;</sup>p&lt;0.05 compared to the H<sub>2</sub>O<sub>2</sub> group.</p></caption>
<graphic xlink:href="IJMM-49-04-05100-g00.tif"/></fig>
<fig id="f5-ijmm-49-04-05100" position="float">
<label>Figure 5</label>
<caption>
<p>Sirtuin 1 (SIRT1) regulates the expression of proliferator-activated receptor-gamma coactivator 1&#x003B1; (PGC-1&#x003B1;), as well as the apoptosis and prolifera- tion of HEI-OC1 cells. (A) HEI-OC1 cell apoptosis was measured by Annexin V and propidium iodine staining. (B) The proliferation of HEI-OC1 cells was measured by MTT assay. (C) RT-qPCR analysis of SIRT1 and PGC-1&#x003B1; in HEI-OC1 cells subjected to different treatments. <sup>#</sup>p&lt;0.05 compared to the control group; <sup>&#x0002A;</sup>p&lt;0.05 compared to the H<sub>2</sub>O<sub>2</sub> group. (D) Protein expression analysis of SIRT1 and PGC-1&#x003B1; determined by western blot analysis in HEI-OC1 cells subjected to different treatments. <sup>#</sup>p&lt;0.05 compared to the control group; <sup>&#x0002A;</sup>p&lt;0.05 compared to the H<sub>2</sub>O<sub>2</sub> group.</p></caption>
<graphic xlink:href="IJMM-49-04-05100-g01.tif"/></fig></body></article>
