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<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">OR</journal-id>
<journal-title-group>
<journal-title>Oncology Reports</journal-title>
</journal-title-group>
<issn pub-type="ppub">1021-335X</issn>
<issn pub-type="epub">1791-2431</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/or.2023.8581</article-id>
<article-id pub-id-type="publisher-id">OR-50-1-08581</article-id>
<article-categories>
<subj-group>
<subject>Corrigendum</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>[Corrigendum] Downregulation of Notch1 induces apoptosis and inhibits cell proliferation and metastasis in laryngeal squamous cell carcinoma</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Dai</surname><given-names>Meng-Yuan</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Fang</surname><given-names>Fang</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Zou</surname><given-names>You</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Yi</surname><given-names>Xing</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Ding</surname><given-names>Yong-Jun</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Chen</surname><given-names>Chen</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Tao</surname><given-names>Ze-Zhang</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Chen</surname><given-names>Shi-Ming</given-names></name>
</contrib>
</contrib-group>
<pub-date pub-type="collection">
<month>07</month>
<year>2023</year></pub-date>
<pub-date pub-type="epub">
<day>06</day>
<month>06</month>
<year>2023</year></pub-date>
<volume>50</volume>
<issue>1</issue>
<elocation-id>144</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x00A9; Dai et al.</copyright-statement>
<copyright-year>2023</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.</license-p></license>
</permissions>
</article-meta>
</front>
<body>
<p>Oncol Rep 34: <related-article xmlns:xlink="http://www.w3.org/1999/xlink" related-article-type="corrected-article" vol="34" page="3111" id="RA1" xlink:href="10.3892/or.2015.4274" ext-link-type="doi">3111&#x2013;3119</related-article>, 2015; DOI: 10.3892/or.2015.4274</p>
<p>Following the publication of this article, a concerned reader drew to the authors&#x0027; attention that a pair of the 24 h scratch-wound assay data panels in <xref rid="f4-or-50-1-08581" ref-type="fig">Fig. 4A</xref>, and three of the migration and invasion assay data panels in <xref rid="f4-or-50-1-08581" ref-type="fig">Fig. 4B</xref>, exhibited overlapping sections, suggesting that data which were intended to have shown the results from differently performed experiments had originated from the same sources. In addition, the total number of cases for the LSCC sample data in <xref rid="tII-or-50-1-08581" ref-type="table">Table II</xref> did not reflect the sum of the samples indicated in the &#x2018;negative&#x2019;, &#x2018;positive&#x2019; and &#x2018;strong positive&#x2019; categories.</p>
<p>After having consulted their original data, the authors have realized that <xref rid="tII-or-50-1-08581" ref-type="table">Table II</xref> and <xref rid="f4-or-50-1-08581" ref-type="fig">Fig. 4</xref> contained some inadvertent errors: The authors divided their control group data into two subgroups, namely the non-transfection and negative-shRNA groups, although they overlooked details of the filing system they had devised for saving the data, and mistakenly included images from the non-transfection group in with the negative-shRNA group due to unclear file labeling. Moreover, in <xref rid="tII-or-50-1-08581" ref-type="table">Table II</xref>, the data value for the &#x2018;positive&#x2019; stained samples should have been written as &#x2018;43&#x2019;, not &#x2018;44&#x2019;.</p>
<p>The corrected versions of <xref rid="tII-or-50-1-08581" ref-type="table">Table II</xref> and <xref rid="f4-or-50-1-08581" ref-type="fig">Fig. 4</xref>, which now shows the corrected data for the &#x2018;Negative-shRNA / 24 h&#x2019; experiment in <xref rid="f4-or-50-1-08581" ref-type="fig">Fig. 4A</xref> and the &#x2018;Non-transfection / Invasion&#x2019; and &#x2018;Negative-shRNA / Migration&#x2019; experiments in <xref rid="f4-or-50-1-08581" ref-type="fig">Fig. 4B</xref>, are shown below and on the next page, respectively. The authors sincerely apologize for the errors that were introduced during the preparation of this table and this figure, thank the Editor of <italic>Oncology Reports</italic> for granting them the opportunity to publish this corrigendum, and regret any inconvenience that these mistakes may have caused to the readership.</p>
</body>
<floats-group>
<fig id="f4-or-50-1-08581" position="float">
<label>Figure 4.</label>
<caption><p>Notch1 knockdown inhibits HEp-2 cell migration and invasion abilities. (A) Photomicrograph of scratches made in the shRNA-transfected HEp-2 cell layer showing inhibition of cellular motility in the Notch1-silenced cells as compared with the non-transfected and negative shRNA groups. (B) Representative images of the Transwell assay without (top panel) or with (bottom panel) Matrigel coating after shRNA transfection. (C) Migration assay results showing the number of HEp-2 cells that had migrated through the non-Matrigel coated filters. (D) invasion assay showing the number of cells that had passed through the Matrigel-precoated filters. The cell counts presented are the mean values/field from at least five randomly selected low-power fields (magnification, &#x00D7;200) from three independent experiments (error bars, means &#x00B1; SD). &#x002A;P&#x003C;0.05 compared with the non-transfected group; <sup>#</sup>P&#x003C;0.05 compared with the negative shRNA group.</p></caption>
<graphic xlink:href="or-50-01-08581-g00.jpg"/>
</fig>
<table-wrap id="tII-or-50-1-08581" position="float">
<label>Table II.</label>
<caption><p>QD-IHC detection of Notch1 expression in LSCC and normal vocal polyp tissues.</p></caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="bottom">Sample</th>
<th align="center" valign="bottom">Case</th>
<th align="center" valign="bottom">Negative</th>
<th align="center" valign="bottom">Positive</th>
<th align="center" valign="bottom">Strong positive</th>
<th align="center" valign="bottom">P-value</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Normal vocal polyps</td>
<td align="center" valign="top">31</td>
<td align="center" valign="top">24</td>
<td align="center" valign="top">5</td>
<td align="center" valign="top">2</td>
<td/>
</tr>
<tr>
<td align="left" valign="top">LSCC</td>
<td align="center" valign="top">95</td>
<td align="center" valign="top">11</td>
<td align="center" valign="top"><bold>43</bold></td>
<td align="center" valign="top">41</td>
<td align="center" valign="top">&#x003C;0.01<sup><xref rid="tfn1-or-50-1-08581" ref-type="table-fn">a</xref></sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x00A0;&#x00A0;Without metastasis</td>
<td align="center" valign="top">72</td>
<td align="center" valign="top">11</td>
<td align="center" valign="top">39</td>
<td align="center" valign="top">22</td>
<td align="center" valign="top">&#x003C;0.01<sup><xref rid="tfn1-or-50-1-08581" ref-type="table-fn">a</xref></sup></td>
</tr>
<tr>
<td align="left" valign="top">&#x00A0;&#x00A0;With metastasis</td>
<td align="center" valign="top">23</td>
<td align="center" valign="top">0</td>
<td align="center" valign="top">4</td>
<td align="center" valign="top">19</td>
<td align="center" valign="top">&#x003C;0.01<sup><xref rid="tfn2-or-50-1-08581" ref-type="table-fn">b</xref></sup></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="tfn1-or-50-1-08581"><label>a</label><p>When compared with normal vocal polyp tissues.</p></fn>
<fn id="tfn2-or-50-1-08581"><label>b</label><p>When compared with normal vocal polyp tissues and LSCC without metastasis. QD-IHC, quantum dot immunohistochemistry; LSCC, laryngeal squamous cell carcinoma.</p></fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</article>
