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<article xml:lang="en" article-type="retraction" xmlns:xlink="http://www.w3.org/1999/xlink">
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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">IJMM</journal-id>
<journal-title-group>
<journal-title>International Journal of Molecular Medicine</journal-title></journal-title-group>
<issn pub-type="ppub">1107-3756</issn>
<issn pub-type="epub">1791-244X</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name></publisher></journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/ijmm.2024.5459</article-id>
<article-id pub-id-type="publisher-id">ijmm-55-02-05459</article-id>
<article-categories>
<subj-group>
<subject>Retraction</subject></subj-group></article-categories>
<title-group>
<article-title>[Retracted] PLGA/poloxamer nanoparticles loaded with EPAS1 siRNA for the treatment of pancreatic cancer <italic>in vitro</italic> and <italic>in vivo</italic></article-title></title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Pan</surname><given-names>Xinting</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Zhu</surname><given-names>Qingyun</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Sun</surname><given-names>Yunbo</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Li</surname><given-names>Liandi</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Zhu</surname><given-names>Yunpeng</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Zhao</surname><given-names>Zhihui</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Zuo</surname><given-names>Jianxin</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Fang</surname><given-names>Wei</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Li</surname><given-names>Kun</given-names></name></contrib></contrib-group>
<pub-date pub-type="collection">
<month>02</month>
<year>2025</year></pub-date>
<pub-date pub-type="epub">
<day>18</day>
<month>11</month>
<year>2024</year></pub-date>
<volume>55</volume>
<issue>2</issue>
<elocation-id>18</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x000A9; 2024 Pan et al.</copyright-statement>
<copyright-year>2024</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.</license-p></license></permissions></article-meta></front>
<body>
<p>Int J Mol Med 35: <related-article id="RA1" related-article-type="retracted-article" vol="35" page="995" ext-link-type="doi" xlink:href="10.3892/ijmm.2015.2096">995-1002</related-article>, 2015; DOI: 10.3892/ijmm.2015.2096</p>
<p>Following the publication of this article, a concerned reader drew to the Editor's attention that, in the tumor tissue images shown in Fig. 5A and B on p. 1001, there were two pairs of overlapping data panels, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the same original sources. Subsequently, after having conducted a separate investigation in the Editorial Office, it came to light that there were also matching data panels intending to show the results from different experiments in the flow cytometric plots shown in Fig. 2; moreover, there appeared to be potential issues with the presentation of some of the western blots in Fig. 3.</p>
<p>Although the possibility of a corrigendum was considered, upon reflection, the Editor of <italic>International Journal of Molecular Medicine</italic> has decided that, owing to the number of problems that were identified with the data in the published paper, the article should be retracted from the publication on account of data mishandling issues and an overall lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused, and thanks the interested reader for initially drawing this matter to our attention.</p></body></article>
