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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">OL</journal-id>
<journal-title-group>
<journal-title>Oncology Letters</journal-title>
</journal-title-group>
<issn pub-type="ppub">1792-1074</issn>
<issn pub-type="epub">1792-1082</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/ol.2025.15042</article-id>
<article-id pub-id-type="publisher-id">OL-29-6-15042</article-id>
<article-categories>
<subj-group>
<subject>Retraction</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>[Retracted] 5‑Fluorouracil‑induced apoptosis in colorectal cancer cells is caspase‑9‑dependent and mediated by activation of protein kinase C‑&#x03B4;</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Mhaidat</surname><given-names>Nizar M.</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Bouklihacene</surname><given-names>Mohammed</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Thorne</surname><given-names>Rick F.</given-names></name>
</contrib>
</contrib-group>
<pub-date pub-type="collection">
<month>06</month>
<year>2025</year></pub-date>
<pub-date pub-type="epub">
<day>14</day>
<month>04</month>
<year>2025</year></pub-date>
<volume>29</volume>
<issue>6</issue>
<elocation-id>296</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2025 Mhaidat et al.</copyright-statement>
<copyright-year>2025</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.</license-p></license>
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<body>
<p>Oncol Lett 8: <related-article xmlns:xlink="http://www.w3.org/1999/xlink" related-article-type="retracted-article" vol="8" page="699" id="RA1" xlink:href="10.3892/ol.2014.2211" ext-link-type="doi">699&#x2013;704</related-article>, 2014; DOI: 10.3892/ol.2014.2211</p>
<p>Following the publication of the above paper, concerns were raised about the presentation of data in Figs. 6 and 9. In Fig. 6 (and Fig. 9, which shared the same control &#x03B2;-actin protein bands), it was drawn to the Editor&#x0027;s attention that the leftmost pair of the &#x03B2;-actin bands shown for the HCT116 experimental gels were strikingly similar to the rightmost &#x03B2;-actin bands featured for the SW480 gels; furthermore, in Fig. 9, the phosphorylated (P)-PKC&#x03B5; and PKC&#x03B5; panels for both the HCT116 and SW480 experiments also looked remarkably similar.</p>
<p>Upon investigating this matter independently in the Editorial Office, the Editor of <italic>Oncology Letters</italic> has decided that this paper should be retracted from the Journal on the grounds of a lack of confidence in the presented data, with probable errors having been made in compiling the data in these figures. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.</p>
</body>
</article>
