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<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Molecular Medicine Reports</journal-id>
<journal-title-group>
<journal-title>Molecular Medicine Reports</journal-title>
</journal-title-group>
<issn pub-type="ppub">1791-2997</issn>
<issn pub-type="epub">1791-3004</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/mmr.2025.13622</article-id>
<article-id pub-id-type="publisher-id">MMR-32-4-13622</article-id>
<article-categories>
<subj-group>
<subject>Retraction</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>[Retracted] Inhibition of TLR4 protects rat islets against lipopolysaccharide-induced dysfunction </article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Wang</surname><given-names>Xiao</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Ge</surname><given-names>Qin Min</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Bian</surname><given-names>Fan</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Dong</surname><given-names>Yan</given-names></name>
</contrib>
<contrib contrib-type="author"><name><surname>Huang</surname><given-names>Chun Mei</given-names></name>
</contrib>
</contrib-group>
<pub-date pub-type="collection"><month>10</month><year>2025</year></pub-date>
<pub-date pub-type="epub"><day>16</day><month>07</month><year>2025</year></pub-date>
<volume>32</volume>
<issue>4</issue>
<elocation-id>257</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2025 Wang et al.</copyright-statement>
<copyright-year>2025</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.</license-p></license>
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<body>
<p>Mol Med Rep 15: <related-article xmlns:xlink="http://www.w3.org/1999/xlink" related-article-type="retracted-article" vol="15" page="805" id="RA1" xlink:href="10.3892/mmr.2016.6097" ext-link-type="doi">805&#x2013;812</related-article>, 2017; DOI: 10.3892/mmr.2016.6097</p>
<p>Following the publication of the above paper, it was drawn to the Editor&#x0027;s attention by a concerned reader that, regarding the lower two flow cytometric plots shown in Fig. 3A on p. 809 (namely, the plots for the &#x2018;anti-TLR4&#x002B;LPS&#x2019; and &#x2018;TLR4-shRNA&#x002B;LPS&#x2019; experiments), these appeared to show similar groupings of dots, which would not have been anticipated if these experiments had been performed discretely under different experimental conditions, suggesting a fundamental flaw either in the way in which these experiments were performed, or in how the results were outputted.</p>
<p>The Editor of <italic>Molecular Medicine Reports</italic> has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.</p>
</body>
</article>
