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<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">OR</journal-id>
<journal-title-group>
<journal-title>Oncology Reports</journal-title>
</journal-title-group>
<issn pub-type="ppub">1021-335X</issn>
<issn pub-type="epub">1791-2431</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/or.2025.8971</article-id>
<article-id pub-id-type="publisher-id">OR-54-5-08971</article-id>
<article-categories>
<subj-group>
<subject>Expression of Concern</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>[Expression of Concern] Lysine demethylase 2A promotes the progression of ovarian cancer by regulating the PI3K pathway and reversing epithelial-mesenchymal transition</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Lu</surname><given-names>Dan-Hua</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Yang</surname><given-names>Jiang</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Gao</surname><given-names>Li-Kun</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Min</surname><given-names>Jie</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Tang</surname><given-names>Jian-Ming</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Hu</surname><given-names>Ming</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Li</surname><given-names>Yang</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Li</surname><given-names>Su-Ting</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Chen</surname><given-names>Jing</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
<contrib contrib-type="author"><name><surname>Hong</surname><given-names>Li</given-names></name>
<xref rid="af1-or-54-5-08971" ref-type="aff"/><xref rid="af2-or-54-5-08971" ref-type="aff"/></contrib>
</contrib-group>
<aff id="af1-or-54-5-08971">Department of Gynaecology and Obstetrics, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China</aff>
<aff id="af2-or-54-5-08971">Department of Pathology, Molecular Diagnostics Laboratory, University of Michigan, Ann Arbor, MI 48109, USA</aff>
<pub-date pub-type="collection"><month>11</month><year>2025</year></pub-date>
<pub-date pub-type="epub"><day>08</day><month>08</month><year>2025</year></pub-date>
<volume>54</volume>
<issue>5</issue>
<elocation-id>138</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2025 Lu et al.</copyright-statement>
<copyright-year>2025</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.</license-p></license>
</permissions>
</article-meta>
</front>
<body>
<p>Oncol Rep 41: <related-article xmlns:xlink="http://www.w3.org/1999/xlink" related-article-type="object-of-concern" vol="41" page="917" id="RA1" xlink:href="10.3892/or.2018.6888" ext-link-type="doi">917&#x2013;927</related-article>, 2019; DOI: 10.3892/or.2018.6888</p>
<p>Following the publication of this paper, it was drawn to the Editor&#x0027;s attention by a concerned reader that one of the colony-formation assay images shown in Fig. 2D for the SKOV3 experiments was strikingly similar to the &#x2018;SKOV3/0 &#x00B5;M LY294002&#x2019; image shown in Fig. 5E, if one of the dishes were to be rotated 90&#x00B0;. Upon performing an independent analysis of the data in this paper in the Editorial Office, it also came to light that the data shown for the MMP9 blot (A2780 cell line) in Fig. 4E was strikingly similar to the p-mTOR blot (again for the A2780 cell line) in Fig. 5B, suggesting that one of these figures had been assembled incorrectly.</p>
<p>The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further.</p>
</body>
</article>
