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<article xml:lang="en" article-type="expression-of-concern" xmlns:xlink="http://www.w3.org/1999/xlink">
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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">IJMM</journal-id>
<journal-title-group>
<journal-title>International Journal of Molecular Medicine</journal-title></journal-title-group>
<issn pub-type="ppub">1107-3756</issn>
<issn pub-type="epub">1791-244X</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name></publisher></journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/ijmm.2026.5816</article-id>
<article-id pub-id-type="publisher-id">ijmm-57-06-05816</article-id>
<article-categories>
<subj-group>
<subject>Expression of Concern</subject></subj-group></article-categories>
<title-group>
<article-title>[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression</article-title></title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Xu</surname><given-names>Peng</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Tao</surname><given-names>Xuelei</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Zhao</surname><given-names>Chengjin</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Huang</surname><given-names>Qingfeng</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Chang</surname><given-names>Hao</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Ban</surname><given-names>Na</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Bei</surname><given-names>Yuanqi</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Xia</surname><given-names>Xiaojie</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Shen</surname><given-names>Chaoyan</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Wang</surname><given-names>Kun</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Xu</surname><given-names>Li</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Wu</surname><given-names>Peizhang</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Ren</surname><given-names>Jianbing</given-names></name></contrib>
<contrib contrib-type="author">
<name><surname>Wang</surname><given-names>Donglin</given-names></name></contrib></contrib-group>
<pub-date pub-type="collection">
<month>06</month>
<year>2026</year></pub-date>
<pub-date pub-type="epub">
<day>30</day>
<month>03</month>
<year>2026</year></pub-date>
<volume>57</volume>
<issue>6</issue>
<elocation-id>145</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x000A9; 2026 Xu et al.</copyright-statement>
<copyright-year>2026</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.</license-p></license></permissions></article-meta></front>
<body>
<p>Int J Mol Med 40: <related-article id="RA1" related-article-type="object-of-concern" vol="40" page="491" ext-link-type="doi" xlink:href="10.3892/ijmm.2017.3023">491-498</related-article>, 2017; DOI: 10.3892/ijmm.2017.3023</p>
<p>Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the paraffin-embedded glioma tissue sections shown in Fig. 2A on p. 494, the Ki-67/Grade III and DTX3L/Grade IV data panels contained an overlapping section, suggesting that these data panels were derived from the same original source where different experimental groups were reported. In addition, GAPDH control western blots featured in Figs. 1C and 4E were found to be strikingly similar, even though the experimental conditions reported for these figure parts were different.</p>
<p>The authors have been contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in their paper, and we are awaiting their response. Due to the fact that we have been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of these potential problems while the Editorial Office continues to investigate this matter further.</p></body></article>
