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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">OL</journal-id>
<journal-title-group>
<journal-title>Oncology Letters</journal-title>
</journal-title-group>
<issn pub-type="ppub">1792-1074</issn>
<issn pub-type="epub">1792-1082</issn>
<publisher>
<publisher-name>D.A. Spandidos</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3892/ol.2026.15936</article-id>
<article-id pub-id-type="publisher-id">OL-33-1-15936</article-id>
<article-categories>
<subj-group>
<subject>Retraction</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>[Retracted] Metformin upregulates E-cadherin and inhibits B16F10 cell motility, invasion and migration</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Liang</surname><given-names>Guanzhao</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Ding</surname><given-names>Minglei</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Lu</surname><given-names>Haitao</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Cao</surname><given-names>Na</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Niu</surname><given-names>Yandong</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Gao</surname><given-names>Yang</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Lu</surname><given-names>Jie</given-names></name></contrib>
</contrib-group>
<pub-date pub-type="collection">
<month>01</month><year>2027</year></pub-date>
<pub-date pub-type="epub">
<day>03</day><month>11</month><year>2026</year></pub-date>
<volume>33</volume>
<issue>1</issue>
<elocation-id>1</elocation-id>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2026 Liang et al.</copyright-statement>
<copyright-year>2026</copyright-year>
<license license-type="open-access">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.</license-p>
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<body>
<p>Oncol Lett 10: <related-article xmlns:xlink="http://www.w3.org/1999/xlink" id="RA1" related-article-type="retracted-article" vol="10" page="1527" ext-link-type="doi" xlink:href="10.3892/ol.2015.3475">1527-1532</related-article>, 2015; DOI: 10.3892/ol.2015.3475</p>
<p>Following the publication of the above paper, it has been drawn to the Editor&#x0027;s attention by a concerned reader that the data panels showing the results of invasion assay experiments in Fig. 3A on p. 1530 contained a number of overlapping sections of data, such that these panels, which were intended to show the results of four different experimental conditions, had all apparently been derived from the same original source. In addition, regarding the western blots shown in Fig. 4B, the protein bands shown for the E-cadherin experiments in the pair of lanes on the left in this figure part looked remarkably similar, suggesting that this protein band may have been duplicated within the gel.</p>
<p>Given that these issues have come to light, the Editor of <italic>Oncology Letters</italic> has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. After contacting the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.</p>
</body>
</article>
