Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes

  • Authors:
    • Oktay Kaya
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  • Published online on: July 29, 2016     https://doi.org/10.3892/br.2016.730
  • Pages: 367-370
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Abstract

The aim of the present study was to examine how a 4-week exercise program affects the serum levels of certain cytokines in Taekwondo athletes. The study involved 10 elite male Taekwondo athletes (mean age, 20.67±0.24 years; mean weight, 65.45±1.69 kg) who were studying at the Physical Education and Sports High School of Selçuk University (Konya, Turkey) in June 2014. The subjects were involved in a Taekwondo exercise program on every weekday for 4 weeks. The subjects were also engaged in an exercise to exhaustion session twice; once before starting the 4‑week exercise program and once upon completion of the program. Blood samples were collected from the subjects in four rounds: During rest, upon fatigue, and before and after the 4‑week exercise program. These samples were analyzed to establish the serum levels of interferon‑γ (IFN-γ), tumor necrosis factor‑α (TNF‑α), interleukin (IL)‑2 and IL‑6 using enzyme‑linked immunosorbent assay test kits. Pre‑ and post‑exercise program, the IFN‑γ and TNF‑α levels did not show any significant difference. When compared with the pre‑exercise levels, serum IL‑2 levels of the subjects were found to be elevated after the 4-week exercise program. The highest serum IL‑6 values were established after the subjects were exercised to fatigue before the exercise program was initiated (P<0.05). The 4‑week exercise program resulted in a decrease in IL‑6 levels (P<0.05). The findings of the study indicate that a 4‑week exercise program did not result in significant changes in IFN‑γ and TNF‑α levels, but led to an increase in IL‑2 levels. The notable finding of the present study is that a 4‑week exercise program reduces cellular immune functions and, thus, the levels of IL‑6, which negatively influences performance.
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September-2016
Volume 5 Issue 3

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Spandidos Publications style
Kaya O: Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes. Biomed Rep 5: 367-370, 2016
APA
Kaya, O. (2016). Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes. Biomedical Reports, 5, 367-370. https://doi.org/10.3892/br.2016.730
MLA
Kaya, O."Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes". Biomedical Reports 5.3 (2016): 367-370.
Chicago
Kaya, O."Effect of a four-week exercise program on the secretion of IFN-γ, TNF-α, IL-2 and IL-6 cytokines in elite Taekwondo athletes". Biomedical Reports 5, no. 3 (2016): 367-370. https://doi.org/10.3892/br.2016.730