- Timosaponin A-III reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway
JIE-RU CHEN et al, 2016, International Journal of Oncology CrossRef - Meta analysis of bioactive compounds, miRNA, siRNA and cell death regulators as sensitizers to doxorubicin induced chemoresistance
Sruthi Sritharan et al, 2022, Apoptosis CrossRef - Piperlongumine induces apoptosis and G2/M phase arrest in human osteosarcoma cells by regulating ROS/PI3K/Akt pathway
Jinfeng Zhou et al, 2020, Toxicology in Vitro CrossRef - Harmine and Piperlongumine Revert TRIB2-Mediated Drug Resistance
Susana Machado et al, 2020, Cancers CrossRef - Overview of piperlongumine analogues and their therapeutic potential
Peng Zhu et al, 2021, European Journal of Medicinal Chemistry CrossRef - Convallatoxin Inhibits Cell Proliferation and Induces Cell Apoptosis by Attenuating the Akt-E2F1 Signaling Pathway in K562 Cells
Man Li et al, 2022, Natural Product Communications CrossRef - Reversal of cisplatin resistance in oral squamous cell carcinoma by piperlongumine loaded smart nanoparticles through inhibition of Hippo-YAP signaling pathway
Pratikshya Sa et al, 2024, Translational Research CrossRef - Synergistic anticancer activity of doxorubicin and piperlongumine on DU-145 prostate cancer cells – The involvement of carbonyl reductase 1 inhibition
Kamil Piska et al, 2019, Chemico-Biological Interactions CrossRef - Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer
Yin‑Ju Chen et al, 2017, Oncology Letters CrossRef - Piplartine (piperlongumine), oxidative stress, and use in cancer
Daniel Pereira Bezerra, 2021, Cancer CrossRef - Let-7d increases ovarian cancer cell sensitivity to a genistein analog by targeting c-Myc
Ying-Xia Ning et al, 2017, Oncotarget CrossRef - N-myristoylation of Antimicrobial Peptide CM4 Enhances Its Anticancer Activity by Interacting With Cell Membrane and Targeting Mitochondria in Breast Cancer Cells
Caiyun Li et al, 2018, Frontiers in Pharmacology CrossRef - A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells
Maiara de S. Oliveira et al, 2019, Redox Biology CrossRef - Quercetin reverses the doxorubicin resistance of prostate cancer cells by downregulating the expression of c‑met
Yan Shu et al, 2017, Oncology Letters CrossRef - Piperlongumine, a potent anticancer phytotherapeutic: Perspectives on contemporary status and future possibilities as an anticancer agent
Surya Kant Tripathi et al, 2020, Pharmacological Research CrossRef - Piperlongumine Inhibits Akt Phosphorylation to Reverse Resistance to Cisplatin in Human Non-Small Cell Lung Cancer Cells via ROS Regulation
Chao Zhang et al, 2019, Frontiers in Pharmacology CrossRef - A Derivative of Piperlongumine and Ligustrazine as a Potential Thioredoxin Reductase Inhibitor in Drug-Resistant Hepatocellular Carcinoma
Jianqiang Qian et al, 2021, Journal of Natural Products CrossRef - Triptolide promotes ferroptosis by suppressing Nrf2 to overcome leukemia cell resistance to doxorubicin
Xia Wu et al, 2022, Molecular Medicine Reports CrossRef - Piperlongumine (piplartine) as a lead compound for anticancer agents – Synthesis and properties of analogues: A mini-review
Kamil Piska et al, 2018, European Journal of Medicinal Chemistry CrossRef - The Potential of Plant-Derived Extracts and Compounds to Augment Anticancer Effects of Chemotherapeutic Drugs
Chu Xin Ng et al, 2022, Nutrition and Cancer CrossRef - Alkaloid-based modulators of the PI3K/Akt/mTOR pathway for cancer therapy: Understandings from pharmacological point of view
Fatima Zohra Mokhfi et al, 2024, Chemico-Biological Interactions CrossRef