1. Metformin attenuates albumin-induced alterations in renal tubular cells in vitro
    Soumaya Allouch et al, 2017, J Cell Physiol CrossRef
  2. Inhibitory effect of metformin combined with gemcitabine on pancreatic cancer cells in vitro and in vivo
    Yuqi Shi et al, 2016 CrossRef
  3. Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells
    Nipun Saini et al, 2017 CrossRef
  4. Screening Novel Molecular Targets of Metformin in Breast Cancer by Proteomic Approach
    Lobna Al-Zaidan et al, 2017, Front. Public Health CrossRef
  5. Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway
    Nahla E El-Ashmawy et al, 2017, Tumour Biol. CrossRef
  6. Metformin and epothilone A treatment up regulate pro-apoptotic PARP-1, Casp-3 and H2AX genes and decrease of AKT kinase level to control cell death of human hepatocellular carcinoma and ovary adenocarcinoma cells
    Aneta Rogalska et al, 2018, Toxicology in Vitro CrossRef
  7. Quantitative assessment of cell fate decision between autophagy and apoptosis
    Bing Liu et al, 2017, Sci Rep CrossRef
  8. Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes
    Maria Eduarda Azambuja Amaral et al, 2018, Invest New Drugs CrossRef
  9. A 5′ AMP-Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral Squamous Cell Carcinoma
    Jing-Ru Weng et al, 2018, Basic Clin Pharmacol Toxicol CrossRef
  10. Inhibiting ROS-TFE3-dependent autophagy enhances the therapeutic response to metformin in breast cancer
    Miduo Tan et al, 2018, Free Radical Research CrossRef
  11. Relationship between diabetes and respiratory diseases. Clinical and therapeutic aspects
    D. Visca et al, 2018, Pharmacological Research CrossRef
  12. Taurine rescues the arsenic-induced injury in the pancreas of rat offsprings and in the INS-1 cells
    Qiaoting Zhang et al, 2019, Biomedicine & Pharmacotherapy CrossRef
  13. null
    Jared M. Campbell, 2018 CrossRef
  14. High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells
    Sharon Varghese et al, 2019, Biomolecules CrossRef
  15. Metformin Inhibits Growth of Breast Cancer Cell T47 through Decreasing Expression of Protein P53, BCL2 and Cyclin D1
    Irma Yanti Rangkuti et al, 2019, J Med Res Innov CrossRef
  16. Fibroblasts rescue oral squamous cancer cell from metformin-induced apoptosis via alleviating metabolic disbalance and inhibiting AMPK pathway.
    Zhuoyuan Zhang et al, 2019, Cell Cycle CrossRef
  17. Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells
    Yongchen Liu et al, 2017, Cancer Sci CrossRef
  18. Metformin reverses mesenchymal phenotype of primary breast cancer cells through STAT3/NF-κB pathways.
    José Esparza-López et al, 2019, BMC Cancer CrossRef
  19. Insights into new mechanisms and models of cancer stem cell multidrug resistance
    Y. Garcia-Mayea et al, 2019, Seminars in Cancer Biology CrossRef
  20. The Photomodulation Activity of Metformin Against Oral Microbiome.
    Shima Afrasiabi et al, 2019, J Lasers Med Sci CrossRef
  21. Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification
    Archana Bhaw-Luximon et al, 2016, J Cancer Res Clin Oncol CrossRef
  22. Prevention and treatment of cancer targeting chronic inflammation: research progress, potential agents, clinical studies and mechanisms
    Yong Zhang et al, 2017, Sci. China Life Sci. CrossRef
  23. Metformin-Encapsulated Liposome Delivery System: An Effective Treatment Approach against Breast Cancer
    Snehal K. Shukla et al, 2019, Pharmaceutics CrossRef
  24. Recuperative effect of metformin loaded polydopamine nanoformulation promoting EZH2 mediated proteasomal degradation of phospho-α-synuclein in Parkinson’s disease model
    Mo. Nadim Sardoiwala et al, 2019, Nanomedicine: Nanotechnology, Biology and Medicine CrossRef
  25. A systematic flux analysis approach to identify metabolic vulnerabilities in human breast cancer cell lines
    Sheree D. Martin et al, 2019, Cancer Metab CrossRef
  26. Metformin’s Effects on Apoptosis of Esophageal Carcinoma Cells and Normal Esophageal Epithelial Cells: An In Vitro Comparative Study
    Jianwei Peng et al, 2020, BioMed Research International CrossRef
  27. Anticancer mechanisms of metformin: A review of the current evidence.
    Bin Zhao et al, 2020, Life Sci CrossRef
  28. Anti-tumor activity of metformin: from metabolic and epigenetic perspectives
    Xilan Yu et al, 2017, Oncotarget CrossRef
  29. Redox-dependent modulation of metformin contributes to enhanced sensitivity of esophageal squamous cell carcinoma to cisplatin
    Pin Dong Li et al, 2017, Oncotarget CrossRef
  30. Biguanide–transition metals complexes as potential drug for hyperglycemia treatment
    Stephanny Villamizar-Delgado et al, 2020, RSC Adv. CrossRef
  31. Cytotoxic Effects of Plant Sap-Derived Extracellular Vesicles on Various Tumor Cell Types
    Kimin Kim et al, 2020, JFB CrossRef
  32. Real‑time assessment of platinum sensitivity of primary culture from a patient with ovarian cancer with extensive metastasis and the platinum sensitivity enhancing effect by metformin
    Yingzhao Liu et al, 2018, Oncol Lett CrossRef
  33. Metformin‑induced apoptosis facilitates degradation of the cellular caspase 8 (FLICE)‑like inhibitory protein through a caspase‑dependent pathway in human renal cell carcinoma A498 cells
    Ji‑Hoon Jang et al, 2018, Oncol Lett CrossRef
  34. Oxidative stress and TGF-β1 induction by metformin in MCF-7 and MDA-MB-231 human breast cancer cells are accompanied with the downregulation of genes related to cell proliferation, invasion and metastasis
    Poliana C. Marinello et al, 2020, Pathology - Research and Practice CrossRef
  35. An update on the effectiveness of metformin alone and with chemotherapy drugs on tumor cells
    Norah Saeed Al-Zahrani et al, 2020, Eur. J. Cell Sci. CrossRef
  36. Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells
    Maritza P. Garrido et al, 2020, Pharmaceuticals CrossRef
  37. Metformin partially reverses the inhibitory effect of co-culture with ER-/PR-/HER2+ breast cancer cells on biomarkers of monocyte antitumor activity
    Zoheir Dahmani et al, 2020, PLoS ONE CrossRef
  38. Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities
    Luciano Garofano et al, 2021, Nat Cancer CrossRef
  39. Double benefit of metformin treatment: improved bladder function in cyclophosphamide-induced cystitis and enhanced cytotoxicity in cancer cells
    Seckin Engin et al, 2021, Naunyn-Schmiedeberg's Arch Pharmacol CrossRef
  40. Pharmaceutical Drug Metformin and MCL1 Inhibitor S63845 Exhibit Anticancer Activity in Myeloid Leukemia Cells via Redox Remodeling
    Giedrė Valiulienė et al, 2021, Molecules CrossRef
  41. Metformin induces apoptosis via uterus mitochondrial permeability transition pore opening and protects against estradiol benzoate-induced uterine defect and associated pathophysiological disorder in female Wistar rats
    Adeola Oluwakemi Olowofolahan et al, 2021, Bull Natl Res Cent CrossRef
  42. Peroxiredoxin 1 is essential for natamycin-triggered apoptosis and protective autophagy in hepatocellular carcinoma.
    Yao An et al, 2021, Cancer Lett CrossRef
  43. In Vivo and In Vitro Studies Evaluating the Chemopreventive Effect of Metformin on the Aryl Hydrocarbon Receptor-Mediated Breast Carcinogenesis
    Ali Alhoshani et al, 2021, Saudi Journal of Biological Sciences CrossRef
  44. The Role of AMPK/mTOR Signaling Pathway in Anticancer Activity of Metformin
    Nikola Chomanicova et al, 2021, Physiol Res CrossRef
  45. EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers
    Raquel Luna Yolba et al, 2021, Pharmacol Res Perspect CrossRef
  46. Metformin restores cisplatin cytotoxicity reduced by allantoin in CML in vitro
    Grazielle Paz et al, 2021, World Acad Sci J CrossRef
  47. Metformin sensitizes cholangiocarcinoma cell to cisplatin-induced cytotoxicity through oxidative stress mediated mitochondrial pathway
    Jaroon Wandee et al, 2019, Life Sciences CrossRef
  48. Metformin Increases Sensitivity of Melanoma Cells to Cisplatin by Blocking Exosomal-Mediated miR-34a Secretion
    Lan Ge et al, 2021, Journal of Oncology CrossRef
  49. The mechanism by which imeglimin inhibits gluconeogenesis in rat liver cells
    Guillaume Vial et al, 2021, Endocrino Diabet & Metabol CrossRef
  50. Metformin sensitizes AML cells to chemotherapy through blocking mitochondrial transfer from stromal cells to AML cells
    Ruolan You et al, 2022, Cancer Letters CrossRef
  51. The Diminishment of Novel Endometrial Carcinoma-Derived Stem-like Cells by Targeting Mitochondrial Bioenergetics and MYC
    Laureen P. Helweg et al, 2022, IJMS CrossRef
  52. Microarray analysis of breast cancer gene expression profiling in response to 2-deoxyglucose, metformin, and glucose starvation
    Rita Aoun et al, 2022, Cancer Cell Int CrossRef
  53. Combined treatment with glucagon-like peptide-1 receptor agonist exendin-4 and metformin attenuates breast cancer growth
    Yuki Tanaka et al, 2022, Diabetol Int CrossRef
  54. Metformin as a Potential Antitumor Agent
    Andjela Petrovic et al, 2022 CrossRef
  55. Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification
    Beom-Goo Kang et al, 2023, Cancer Biology & Therapy CrossRef
  56. Metformin and Cervical Cancer Risk in Patients with Newly Diagnosed Type 2 Diabetes: A Population-Based Study in Korea
    Hyun Min Kim et al, 2022, Endocrinol Metab CrossRef
  57. null
    Jared M. Campbell, 2023 CrossRef
  58. The effect of metformin on viability and mitochondrial status of tumor and non-tumor cell line
    Jelena Ljubičić et al, 2022, Medicinski podmladak CrossRef
  59. Metformin: A Promising Antidiabetic Medication for Cancer Treatment
    Wei Mu et al, 2023, CDT CrossRef
  60. The Effect of Metformin on Bad, Bak, and Bim Pro-apoptotic Factors: A Molecular Dynamic Simulation Study
    Navid Jamali et al, 2023, CCTR CrossRef
  61. Metformin Anti-Tumor Effect and Metabolic Reprogramming in Breast Cancer Cells
    Feryal Alharthy et al, 2023, J Biochem Technol CrossRef
  62. Jatonik polyherbal mixture induced rat liver MMPT pore opening in normal Wistar rat: In vitro and in vivo studies
    Olabinri.P. Folashade et al, 2023, Chinese Herbal Medicines CrossRef
  63. Demonstrating drug treatment efficacies by monitoring superoxide dynamics in human lung cancer cells with time‐lapse fluorescence microscopy
    Shalaka Konjalwar et al, 2023, Journal of Biophotonics CrossRef
  64. Metformin and Aspirin: Anticancer effects on A549 and PC3 cancer cells and the mechanisms of action
    Farzaneh Motafeghi et al, 2023 CrossRef
  65. Metformin Loaded Zein Polymeric Nanoparticles to Augment Antitumor Activity against Ehrlich Carcinoma via Activation of AMPK Pathway: D-Optimal Design Optimization, In Vitro Characterization, and In Vivo Study
    Yasmina Elmahboub et al, 2024, Molecules CrossRef
  66. Metformin: From Diabetes to Cancer—Unveiling Molecular Mechanisms and Therapeutic Strategies
    Emilia Amengual-Cladera et al, 2024, Biology CrossRef