1. Stachyose Improves Inflammation through Modulating Gut Microbiota of High-Fat Diet/Streptozotocin-Induced Type 2 Diabetes in Rats
    Guimei Liu et al, 2018, Mol. Nutr. Food Res. CrossRef
  2. Metformin attenuates folic-acid induced renal fibrosis in mice
    Hao Yi et al, 2018, J Cell Physiol CrossRef
  3. Pumpkin polysaccharide modifies the gut microbiota during alleviation of type 2 diabetes in rats
    Guimei Liu et al, 2018, International Journal of Biological Macromolecules CrossRef
  4. Simvastatin ameliorates diabetic nephropathy by attenuating oxidative stress and apoptosis in a rat model of streptozotocin-induced type 1 diabetes.
    Nawal M Al-Rasheed et al, 2018, Biomed Pharmacother CrossRef
  5. Oxidative stress in autosomal dominant polycystic kidney disease: player and/or early predictor for disease progression?
    Asmin Andries et al, 2018, Pediatr Nephrol CrossRef
  6. HL156A, a novel pharmacological agent with potent adenosine-monophosphate-activated protein kinase (AMPK) activator activity ameliorates renal fibrosis in a rat unilateral ureteral obstruction model
    Bodokhsuren Tsogbadrakh et al, 2018, PLoS ONE CrossRef
  7. null
    Isabel Nguyen et al, 2019 CrossRef
  8. Thymoquinone Attenuates Cardiomyopathy in Streptozotocin-Treated Diabetic Rats.
    Mustafa S Atta et al, 2018, Oxid Med Cell Longev CrossRef
  9. Metformin attenuates renal medullary hypoxia in diabetic nephropathy through inhibition uncoupling protein-2
    Michael Christensen et al, 2018, Diabetes Metab Res Rev CrossRef
  10. Relationship between transforming growth factor-β1 and type 2 diabetic nephropathy risk in Chinese population
    Tianbiao Zhou et al, 2018, BMC Med Genet CrossRef
  11. Metformin modulates immune cell infiltration into the kidney during unilateral ureteral obstruction in mice
    Michael Christensen et al, 2019, Physiol Rep CrossRef
  12. null
    Sanket N. Patel et al, 2019 CrossRef
  13. Urinary Metabolomics Analysis Reveals the Anti-diabetic Effect of Stachyose in High-Fat Diet/Streptozotocin-Induced Type 2 Diabetic Rats
    Li Liang et al, 2019, Carbohydrate Polymers CrossRef
  14. Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditions
    Maria Szrejder et al, 2019, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease CrossRef
  15. Effect of a polyherbal formulation in streptozotocin-induced diabetic nephropathy in wistar rats
    KanalaSomasekhar Reddy et al, 2019, Indian J Pharmacol CrossRef
  16. Combined effects of metformin and photobiomodulation improve the proliferation phase of wound healing in type 2 diabetic rats
    Mohammad Bagheri et al, 2020, Biomedicine & Pharmacotherapy CrossRef
  17. Digestibility of squash polysaccharide under simulated salivary, gastric and intestinal conditions and its impact on short-chain fatty acid production in type-2 diabetic rats
    Li Liang et al, 2020, Carbohydrate Polymers CrossRef
  18. Mangiferin Alleviates Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice through Regulating the PTEN/PI3K/Akt Signaling Pathway.
    Yanyan Song et al, 2020, J Diabetes Res CrossRef
  19. Salidroside ameliorates diabetic nephropathy in rats by activating renal AMPK/SIRT1 signaling pathway
    Ali A. Shati, 2020, J Food Biochem CrossRef
  20. Role of Impaired Nutrient and Oxygen Deprivation Signaling and Deficient Autophagic Flux in Diabetic CKD Development: Implications for Understanding the Effects of Sodium-Glucose Cotransporter 2-Inhibitors
    Milton Packer, 2020, JASN CrossRef
  21. Destruction of the blood-retina barrier in diabetic retinopathy depends on angiotensin-converting enzyme-mediated TGF-β1/Smad signaling pathway activation
    Ping Sun et al, 2020, International Immunopharmacology CrossRef
  22. Significance of Metformin Use in Diabetic Kidney Disease
    Daiji Kawanami et al, 2020, IJMS CrossRef
  23. The physiological and molecular mechanisms to maintain water and salt homeostasis in response to high salt intake in Mongolian gerbils (Meriones unguiculatus)
    Zahra Nouri et al, 2020, J Comp Physiol B CrossRef
  24. Evaluation of the neuro‐protective effect of Artemisia judaica extract in a murine diabetic model
    Gadah Albasher et al, 2020, J Food Biochem CrossRef
  25. Protective effects of Artemisia judaica extract compared to metformin against hepatorenal injury in high-fat diet/streptozotocine-induced diabetic rats
    Gadah Albasher et al, 2020, Environ Sci Pollut Res CrossRef
  26. Accelerated Kidney Aging in Diabetes Mellitus
    Jing Guo et al, 2020, Oxidative Medicine and Cellular Longevity CrossRef
  27. Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway.
    Fengtao Li et al, 2020, Eur J Pharmacol CrossRef
  28. Selenium cleome droserifolia nanoparticles (Se-CNPs) and it's ameliorative effects in experimentally induced diabetes mellitus
    H.A. Abdel Maksoud et al, 2020, Clinical Nutrition ESPEN CrossRef
  29. Modulation of reproductive dysfunctions associated with streptozocin-induced diabetes by Artemisia judaica extract in rats fed a high-fat diet
    Gadah Albasher, 2020, Mol Biol Rep CrossRef
  30. Oral Spirulina Platensis Attenuates Hyperglycemia and Exhibits Antinociceptive Effect in Streptozotocin-Induced Diabetic Neuropathy Rat Model

    Mohamed M Abdel-Daim et al, 2020, JPR CrossRef
  31. Effects of HuoxueJiangtang decoction alone or in combination with metformin on renal function and renal cortical mRNA expression in diabetic nephropathy rats
    Xuemei Liu et al, 2020, Pharmaceutical Biology CrossRef
  32. The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
    Kristian Leisegang et al, 2021, Biomedicine & Pharmacotherapy CrossRef
  33. Metformin Protects against Podocyte Injury in Diabetic Kidney Disease
    Sanna Lehtonen, 2020, Pharmaceuticals CrossRef
  34. The impact of ellagic acid on some apoptotic gene expressions: a new perspective for the regulation of pancreatic Nrf-2/NF-κB and Akt/VEGF signaling in CCl4-induced pancreas damage in rats
    Abdullah Aslan et al, 2021, Immunopharmacology and Immunotoxicology CrossRef
  35. Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-β1 Signaling Pathways.
    Hao Yi et al, 2021, Front Cell Dev Biol CrossRef
  36. Kaempferol attenuates diabetic nephropathy in streptozotocin-induced diabetic rats by a hypoglycaemic effect and concomitant activation of the Nrf-2/Ho-1/antioxidants axis
    Ali S. Alshehri, 2021, Archives of Physiology and Biochemistry CrossRef
  37. Mechanism and application of metformin in kidney diseases: An update.
    Anni Song et al, 2021, Biomed Pharmacother CrossRef
  38. Concerted outcome of metformin and low dose of radiation in modulation of cisplatin induced uremic encephalopathy via renal and neural preservation
    Hesham Farouk Hasan et al, 2021, Life Sciences CrossRef
  39. Exogenous glutamine ameliorates diabetic nephropathy in a rat model of type 2 diabetes mellitus through its antioxidant and anti-inflammatory activities
    Maryam Nasri et al, 2020, Archives of Physiology and Biochemistry CrossRef
  40. Quercetin alleviates cadmium chloride-induced renal damage in rats by suppressing endoplasmic reticulum stress through SIRT1-dependent deacetylation of Xbp-1s and eIF2α
    Ghedeir M. Alshammari et al, 2021, Biomedicine & Pharmacotherapy CrossRef
  41. Beneficial effects of metformin on glomerular podocytes in diabetes
    Dorota Rogack et al, 2021, Biochemical Pharmacology CrossRef
  42. Potential Interaction of Fresh Garlic with Metformin during Ischemia-Reperfusion Induced Cardiac Injury in Diabetic Rats
    Syed Mohammed Basheeruddin Asdaq et al, 2021, Evidence-Based Complementary and Alternative Medicine CrossRef
  43. Histological investigation of the protective effect of metformin on testis and sperm parameters in obese rats with type 2 diabetes mellitus
    Özcan BUDAK, 2021 CrossRef
  44. Swertiamarin mitigates nephropathy in high-fat diet/streptozotocin-induced diabetic rats by inhibiting the formation of advanced glycation end products
    Kirti Parwani et al, 2021, Archives of Physiology and Biochemistry CrossRef
  45. Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next?
    Moein Ala et al, 2021, ACS Pharmacol. Transl. Sci. CrossRef
  46. Metformin Causes Hepato-renal Dysfunctions in Obese Male Rats
    Sabry Ali El-Naggar et al, 2021, Braz. arch. biol. technol. CrossRef
  47. Sex-specific effects of metformin and liraglutide on renal pathology and expression of connexin 45 and pannexin 1 following long-term high-fat high-sugar diet
    Martina Luetić et al, 2021, Acta Histochemica CrossRef
  48. Telmisartan attenuates diabetic nephropathy by mitigating oxidative stress and inflammation, and upregulating Nrf2/HO-1 signaling in diabetic rats
    Samar A. Antar et al, 2021, Life Sciences CrossRef
  49. Optimization of germination and ultrasonic‐assisted extraction for the enhancement of γ‐aminobutyric acid in pumpkin seed
    Li Liang et al, 2022, Food Science & Nutrition CrossRef
  50. A Review on Cellular and Molecular Mechanisms Linked to the Development of Diabetes Complications
    Rishabh A. Babel et al, 2021, CDR CrossRef
  51. Potential of honey against the onset of autoimmune diabetes and its associated nephropathy, pancreatitis, and retinopathy in type 1 diabetic animal model
    Sultan Fahad Al Nohair et al, 2022 CrossRef
  52. Syringic Acid: A Potential Natural Compound for the Management of Renal Oxidative Stress and Mitochondrial Biogenesis in Diabetic Rats
    Marzieh Rashedinia et al, 2021, CDDT CrossRef
  53. A Glimpse of Inflammation and Anti-Inflammation Therapy in Diabetic Kidney Disease
    Chongbin Liu et al, 2022, Front. Physiol. CrossRef
    Songül DOĞANAY et al, 2022, KTD CrossRef
  55. Regulatory effects and anti‐inflammatory activity of Trachyspermum ammi (L.) Sprague seeds extract on alleviation of kidney injury in diabetic rats
    Najimeh Zolfaghari et al, 2022, Food Processing Preservation CrossRef
  56. Towards Better Drug Repositioning: Targeted Immunoinflammatory Therapy for Diabetic Nephropathy
    Qin Zhang et al, 2021, CMC CrossRef
  57. Recent Progress in the Diagnosis and Management of Type 2 Diabetes Mellitus in the Era of COVID-19 and Single Cell Multi-Omics Technologies
    Krisztina Kupai et al, 2022, Life CrossRef
  58. Coadministration of L‐alanine and L‐glutamine ameliorate blood glucose levels, biochemical indices and histological features in alloxan‐induced diabetic rats
    Ifeanyi J. Ezeonwumelu et al, 2022, Journal of Food Biochemistry CrossRef
  59. Therapeutic Potential of MgO and MnO Nanoparticles Within the Context of Thyroid Profile and Pancreatic Histology in a Diabetic Rat Model
    Arslan Shaukat et al, 2022, Dose-Response CrossRef
  60. Investigation of the Chemical Composition, Antihyperglycemic and Antilipidemic Effects of Bassia eriophora and Its Derived Constituent, Umbelliferone on High-Fat Diet and Streptozotocin-Induced Diabetic Rats
    Abdulaziz K. Al Mouslem et al, 2022, Molecules CrossRef
  61. Vitamin D and Swimming Exercise Prevent Obesity in Rats under a High-Fat Diet via Targeting FATP4 and TLR4 in the Liver and Adipose Tissue
    Eman Kolieb et al, 2022, IJERPH CrossRef
  62. Implication of the MAPK Signalling Pathway in the Pathogenesis of Diabetic Nephropathy
    Jéssica Barletto Sousa Barros et al, 2019, EMJ Diabet CrossRef
  63. Metformin: new applications for an old drug
    Amirreza Naseri et al, 2022 CrossRef
  64. Agomelatine improves streptozotocin-induced diabetic nephropathy through melatonin receptors/SIRT1 signaling pathway
    Nevertyty M. Mahmoud et al, 2023, International Immunopharmacology CrossRef
  65. Possible renoprotective effect of valsartan/sacubitril versus valsartan and Metformin in rat model of diabetic nephropathy
    Dina Ibrahim Tawfik et al, 2023, J Adv Pharm Educ Res CrossRef
  66. Bioactive compounds rich Mehani formulation ameliorates diabetes and associated inflammatory condition - In vitro and in vivo studies
    Meenakshi R Venkateswaran et al, 2023, South African Journal of Botany CrossRef
  67. Intestinal microbiome diversity of diabetic and non-diabetic kidney disease: Current status and future perspective
    Soumik Das et al, 2023, Life Sciences CrossRef
  68. Exploring the Epigenetic Regulated Modulation of Fibroblast Growth Factor 21 Involvement in High-Fat Diet Associated Parkinson’s Disease in Rats
    Violina Kakoty et al, 2023, ACS Chem. Neurosci. CrossRef
  69. A Review of Medicinal Plants with Renoprotective Activity in Diabetic Nephropathy Animal Models
    I Made Wisnu Adhi Putra et al, 2023, Life CrossRef
  70. Pharmacological management of youth with type 2 diabetes and diabetic kidney disease: a comprehensive review of current treatments and future directions
    Kalie L. Tommerdahl et al, 2023, Expert Opinion on Pharmacotherapy CrossRef
  71. Is metformin neuroprotective against diabetes mellitus-induced neurodegeneration? An updated graphical review of molecular basis
    Fatemeh Karami et al, 2023, Pharmacol. Rep CrossRef
  72. Possible mitigating effect of adropin on lung injury in diabetic rats: Targeting the role of Rho A/Rho‐associated kinase pathway
    Fatma H. Rizk et al, 2023, BioFactors CrossRef
  73. NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy
    Duojun Qiu et al, 2023, Cellular Signalling CrossRef
  74. Metformin and Canagliflozin Are Equally Renoprotective in Diabetic Kidney Disease but Have No Synergistic Effect
    Raphaëlle Corremans et al, 2023, IJMS CrossRef
  75. Hypoglycemia and anxiolysis mediated by levofloxacin treatment in diabetic rats
    Poonam Singh et al, 2023, J Diabetes Metab Disord CrossRef
  76. Roflumilast ameliorates diabetic nephropathy in rats through down-regulation of JAK/STAT signaling pathway
    Priyal Patel et al, 2023, Naunyn-Schmiedeberg's Arch Pharmacol CrossRef
  77. Rodent models to study type 1 and type 2 diabetes induced human diabetic nephropathy
    Amit Talukdar et al, 2023, Mol Biol Rep CrossRef
  78. A sulfonamide chalcone AMPK activator ameliorates hyperglycemia and diabetic nephropathy in db/db mice
    Suchada Kaewin et al, 2023, Biomedicine & Pharmacotherapy CrossRef
  79. Ameliorative effects of Orlistat and metformin either alone or in combination on liver functions, structure, immunoreactivity and antioxidant enzymes in experimentally induced obesity in male rats
    Reham Z. Hamza et al, 2023, Heliyon CrossRef
  80. Metformin beyond an anti-diabetic agent: A comprehensive and mechanistic review on its effects against natural and chemical toxins
    Amirhossein Malaekeh-Nikouei et al, 2023, Biomedicine & Pharmacotherapy CrossRef
  81. Management of spontaneous diabetes mellitus in a companion rat (Rattus norvegicus)
    Julianne E. McCready et al, 2023, Journal of Exotic Pet Medicine CrossRef
  82. DPP-4i versus SGLT2i as modulators of PHD3/HIF-2α pathway in the diabetic kidney
    Emad Samaan et al, 2023, Biomedicine & Pharmacotherapy CrossRef
  83. Alzheimer's disease‐related brain insulin resistance and the prospective therapeutic impact of metformin
    Hamed A. Abosharaf et al, 2023, J Neuroendocrinology CrossRef
  84. Simvastatin mitigates diabetic nephropathy by upregulating farnesoid X receptor and Nrf2/HO-1 signaling and attenuating oxidative stress and inflammation in rats
    Iman H. Hasan et al, 2024, Life Sciences CrossRef