1. 7,8-DHF Treatment Induces Cyr61 Expression to Suppress Hypoxia Induced ER Stress in HK-2 Cells
    Rui Ma et al, 2016, BioMed Research International CrossRef
  2. Airborne PM2.5-Induced Hepatic Insulin Resistance by Nrf2/JNK-Mediated Signaling Pathway
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  3. 7,8-Dihydroxyflavone attenuates TNF-α-induced skin aging in Hs68 human dermal fibroblast cells via down-regulation of the MAPKs/Akt signaling pathways
    Ji Won Choi et al, 2017, Biomedicine & Pharmacotherapy CrossRef
  4. Nrf2/antioxidant pathway mediates β cell self-repair after damage by high-fat diet–induced oxidative stress
    Tsehay Abebe et al, 2017 CrossRef
  5. Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1
    Weixia Sun et al, 2017, Free Radical Biology and Medicine CrossRef
  6. Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein
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  7. Desoxo-narchinol A and Narchinol B Isolated from Nardostachys jatamansi Exert Anti-neuroinflammatory Effects by Up-regulating of Nuclear Transcription Factor Erythroid-2-Related Factor 2/Heme Oxygenase-1 Signaling
    Kwan-Woo Kim et al, 2018, Neurotox Res CrossRef
  8. Activation of cardiac TrkB receptor by its small molecular agonist 7,8-dihydroxyflavone inhibits doxorubicin-induced cardiotoxicity via enhancing mitochondrial oxidative phosphorylation
    Jing Zhao et al, 2018, Free Radical Biology and Medicine CrossRef
  9. Phenethyl isothiocyanate stimulates glucose uptake through the Akt pathway in C2C12 myotubes
    Maiko Chiba et al, 2019, Bioscience, Biotechnology, and Biochemistry CrossRef
  10. Stretching magnitude–dependent inactivation of AKT by ROS led to enhanced p53 mitochondrial translocation and myoblast apoptosis
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  11. Role of GS28 in sodium nitroprusside‐induced cell death in cervical carcinoma cells
    Do Eun Rim et al, 2019, J Biochem Mol Toxicol CrossRef
  12. Diarylheptanoid 1-(4-hydroxyphenyl)-7-phenyl-(6E)-6-hepten-3-one enhances C2C12 myoblast differentiation by targeting membrane estrogen receptors and activates Akt-mTOR and p38 MAPK-NF-κB signaling axes
    Chittipong Tipbunjong et al, 2019, J Nat Med CrossRef
  13. Hepatoprotective potential of 7,8-Dihydroxyflavone against Alcohol and High-Fat Diet induced Liver Toxicity via attenuation of oxido-nitrosative stress and NF-ҡB activation
    Dinesh Kumar et al, 2019, Pharmacological Reports CrossRef
  14. Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage
    Chun-Hu Wu et al, 2019, J Biomed Sci CrossRef
  15. TTB Protects Astrocytes Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury via Activation of Nrf2/HO-1 Signaling Pathway.
    Liang Liu et al, 2019, Front Pharmacol CrossRef
  16. Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist
    Phillip Yang et al, 2016, Experimental Neurology CrossRef
  17. Brain-derived neurotrophic factor mimetic, 7,8-dihydroxyflavone, protects against myocardial ischemia by rebalancing optic atrophy 1 processing.
    Zhen Wang et al, 2019, Free Radic Biol Med CrossRef
  18. 7,8‑Dihydroxyflavone activates Nrf2/HO‑1 signaling pathways and protects against osteoarthritis
    Dawei Cai et al, 2019, Exp Ther Med CrossRef
  19. LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer’s disease
    Chia-Hao Fan et al, 2020, Psychopharmacology CrossRef
  20. TBHQ-Overview of Multiple Mechanisms against Oxidative Stress for Attenuating Methamphetamine-Induced Neurotoxicity
    Yuan-Ling Zhao et al, 2020, Oxidative Medicine and Cellular Longevity CrossRef
  21. The Emerging Role of BDNF/TrkB Signaling in Cardiovascular Diseases
    Peng-Zhou Hang et al, 2021, Life CrossRef
  22. Bone marrow-derived mesenchymal stem cells modulate autophagy in RAW264.7 macrophages via the phosphoinositide 3-kinase/protein kinase B/heme oxygenase-1 signaling pathway under oxygen-glucose deprivation/restoration conditions
    Ning-Fang Wang et al, 2021 CrossRef
  23. Paeoniflorin and Plycyrrhetinic Acid Synergistically Alleviate MPP+/MPTP-Induced Oxidative Stress through Nrf2-Dependent Glutathione Biosynthesis Mechanisms
    Haiying Dong et al, 2021, ACS Chem. Neurosci. CrossRef
  24. Mechanisms underlying unidirectional laminar shear stress-mediated Nrf2 activation in endothelial cells: Amplification of low shear stress signaling by primary cilia
    Tetsuro Ishii et al, 2021, Redox Biology CrossRef
  25. Phenolic-protein interactions in foods and post ingestion: Switches empowering health outcomes
    Hui Guan et al, 2021, Trends in Food Science & Technology CrossRef
  26. Calycosin alleviates H 2 O 2 ‐induced astrocyte injury by restricting oxidative stress through the Akt/Nrf2/ HO ‐1 signaling pathway
    Cheng‐You Lu et al, 2022, Environmental Toxicology CrossRef
  27. 7,8-Dihydroxyflavone alleviates Endoplasmic Reticulum Stress in cafeteria diet-induced metabolic syndrome
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  28. 7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development
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  29. Retinal Vascular Recovery revealed by retinal imaging following neonatal hypoxia ischemia in mice: is there a role for tyrosine kinase receptor modulation?
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  30. The ethanolic extract of Curcuma longa grown in Korea exhibits anti-neuroinflammatory effects by activating of nuclear transcription factor erythroid-2-related factor 2/heme oxygenase-1 signaling pathway
    Kwan-Woo Kim et al, 2022, BMC Complement Med Ther CrossRef
  31. Evolution of Nrf2 Gene Expression in HIT-T15 β-Cells During Chronic Oxidative Stress and Glucose Toxicity
    Tsehay Abebe et al, 2023 CrossRef
  32. Nrf2 and Antioxidant Response in Animal Models of Type 2 Diabetes
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  33. Retinal Vascular Recovery Revealed by Retinal Imaging  Following Neonatal Hypoxia Ischemia in Mice: Is There a Role for Tyrosine Kinase Receptor Modulation?
    Dila Zafer et al, 2022, SSRN Journal CrossRef
  34. 7,8-Dihydroxyflavone Alleviates Endoplasmic Reticulum Stress in Cafeteria Diet-Induced Metabolic Syndrome
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  35. Investigation of the Pharmacokinetic Properties and Theoretical Chemical Activities of 7,8-Dihydroxyflavone and 4'-Dimethylamino-7,8-Dihydroxyflavone
    Muhammed Fatih Karakaya et al, 2023, CPA CrossRef
  36. 7, 8-dihydroxyflavone Ameliorates Cholinergic Dysfunction, Inflammation, Oxidative Stress, and Apoptosis in a Rat Model of Vascular Dementia
    Navneet Dhaliwal et al, 2024, Neurochem Res CrossRef
  37. Antioxidants for Early Treatment of Type 2 Diabetes in Rodents and Humans: Lost in Translation?
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