1. Dihydroartemisinin inhibits catabolism in rat chondrocytes by activating autophagy via inhibition of the NF-κB pathway
   Li-Bo Jiang et al, 2016, Sci Rep CrossRef
2. Sp1 downregulates proinflammatory cytokine-induced catabolic gene expression in nucleus pulposus cells
   Kang Xu et al, 2016 CrossRef
3. MiR-210 facilitates ECM degradation by suppressing autophagy via silencing of ATG7 in human degenerated NP cells
   Cheng Wang et al, 2017, Biomedicine & Pharmacotherapy CrossRef
4. Protective effect of cannabidiol on hydrogen peroxide‑induced apoptosis, inflammation and oxidative stress in nucleus pulposus cells.
   Jie Chen et al, 2016, Mol Med Rep CrossRef
5. Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway
   Xiangyu Deng et al, 2017, Evidence-Based Complementary and Alternative Medicine CrossRef
6. Adrenomedullin protects Leydig cells against lipopolysaccharide-induced oxidative stress and inflammatory reaction via MAPK/NF-κB signalling pathways
   Wei Hu et al, 2017, Sci Rep CrossRef
7. Mechanism of microRNA-21 regulating IL-6 inflammatory response and cell autophagy in intervertebral disc degeneration
   Hao Lin et al, 2017 CrossRef
8. Therapeutic effects of gefitinib-encapsulated thermosensitive injectable hydrogel in intervertebral disc degeneration.
   Zongyou Pan et al, 2018, Biomaterials CrossRef
9. MiR-21 promotes ECM degradation through inhibiting autophagy via the PTEN/akt/mTOR signaling pathway in human degenerated NP cells
   Wen-Jun Wang et al, 2018, Biomedicine & Pharmacotherapy CrossRef
10. TSG-6 secreted by bone marrow mesenchymal stem cells attenuates intervertebral disc degeneration by inhibiting the TLR2/NF-κB signaling pathway
    Hao Yang et al, 2018, Lab Invest CrossRef
11. Duhuo Jisheng Decoction inhibits SDF-1-induced inflammation and matrix degradation in human degenerative nucleus pulposus cells in vitro through the CXCR4/NF-κB pathway
    Zong-chao Liu et al, 2018, Acta Pharmacol Sin CrossRef
12. Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage
    Jinlou Gao et al, 2018, Biosci. Rep. CrossRef
13. MicroRNA-155 suppresses the catabolic effect induced by TNF-α and IL-1β by targeting C/EBPβ in rat nucleus pulposus cells.
    Jie Zhou et al, 0 CrossRef
14. TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux
    Gang Zheng et al, 2018, Osteoarthritis and Cartilage CrossRef
15. Shared KEGG pathways of icariin-targeted genes and osteoarthritis
    Yi Liu et al, 2018, J Cell Biochem CrossRef
16. Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo.
    Deheng Chen et al, 2016, Cell Death Dis CrossRef
17. Autophagy: A double-edged sword in intervertebral disk degeneration.
    Shu-Jun Zhang et al, 0 CrossRef
18. SIRT1 expression is refractory to hypoxia and inflammatory cytokines in nucleus pulposus cells: Novel regulation by HIF-1α and NF-κB signaling
    Xiaofei Wang et al, 2016, Cell Biol Int CrossRef
19. Regulation of a disintegrins and metalloproteinase with thrombospondin motifs 7 during inflammation in nucleus pulposus (NP) cells: role of AP-1, Sp1 and NF-κB signaling
    Xiaofei Wang et al, 2016, Inflamm. Res. CrossRef
20. Tumor necrosis factor-α: a key contributor to intervertebral disc degeneration.
    Cheng Wang et al, 2017, Acta Biochim Biophys Sin (Shanghai) CrossRef
21. Differential regulation of TRP channel gene and protein expression by intervertebral disc degeneration and back pain
    A. Sadowska et al, 2019, Sci Rep CrossRef
22. Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration
    Liang Kang et al, 2019, Oxidative Medicine and Cellular Longevity CrossRef
23. Nicotinamide Phosphoribosyl Transferase Controls NLRP3 Inflammasome Activity Through MAPK and NF-κB Signaling in Nucleus Pulposus Cells, as Suppressed by Melatonin
    Yingjie Huang et al, 2020, Inflammation CrossRef
24. Bromodomain-containing protein 4 inhibition alleviates matrix degradation by enhancing autophagy and suppressing NLRP3 inflammasome activity in NP cells.
    Junmin Hong et al, 2020, J Cell Physiol CrossRef
25. Autophagy and mTOR signaling during intervertebral disc aging and degeneration
    Takashi Yurube et al, 2020, JOR Spine CrossRef
26. The PI3K/Akt pathway: a critical player in intervertebral disc degeneration
    Zhi-Hua Ouyang et al, 2017, Oncotarget CrossRef
27. The treatment of intervertebral disc degeneration using Traditional Chinese Medicine
    Liguo zhu et al, 2020, Journal of Ethnopharmacology CrossRef
28. Interleukin-17A Promotes Human Disc Degeneration by Inhibiting Autophagy Through the Activation of the Phosphatidylinositol 3-Kinase/Akt/Bcl2 Signaling Pathway
    Wen-Si He et al, 2020, World Neurosurgery CrossRef
29. Impact of NF-κB pathway on the apoptosis-inflammation-autophagy crosstalk in human degenerative nucleus pulposus cells
    Weiwei Yi et al, 2019, Aging CrossRef
30. New insights into the interplay between miRNA and autophagy in the ageing of intervertebral disc
    Tao Lan et al, 2020, Ageing Research Reviews CrossRef
31. Targeting mitochondrial dysfunction with small molecules in intervertebral disc aging and degeneration
    Morteza Saberi et al, 2021, GeroScience CrossRef
32. Induced Autophagy of Macrophages and the Regulation of Inflammatory Effects by Perovskite Nanomaterial LaNiO3
    Yang Wei et al, 2021, Front. Immunol. CrossRef
33. Bromodomain-containing protein 7 regulates matrix metabolism and apoptosis in human nucleus pulposus cells through the BRD7-PI3K-YAP1 signaling axis
    Shuangxing Li et al, 2021, Experimental Cell Research CrossRef
34. Atorvastatin inhibited TNF-α induced matrix degradation in rat nucleus pulposus cells by suppressing NLRP3 inflammasome activity and inducing autophagy through NF-κB signaling
    Jiancong Chen et al, 2021, Cell Cycle CrossRef
35. Role of autophagy in intervertebral disc degeneration
    Rebecca Kritschil et al, 2021, J Cell Physiol CrossRef
36. MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells
    Jie Zhou et al, 2019, Life Sciences CrossRef
37. Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells
    Chenglong Xie et al, 2022, Front. Cell Dev. Biol. CrossRef
38. IL‐17 in intervertebral disc degeneration: Mechanistic insights and therapeutic implications
    Jing‐Hua Tan et al, 2022, Cell Biology International CrossRef
39. The Role of IL-17-Mediated Inflammatory Processes in the Pathogenesis of Intervertebral Disc Degeneration and Herniation: A Comprehensive Review
    Kaori Suyama et al, 2022, Front. Cell Dev. Biol. CrossRef
40. Mechanism of the Mitogen-Activated Protein Kinases/Mammalian Target of Rapamycin Pathway in the Process of Cartilage Endplate Stem Cell Degeneration Induced by Tension Load
    Yu Zhang et al, 2022, Global Spine Journal CrossRef
41. BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells
    Quan Xiao et al, 2022, Stem Cells International CrossRef
42. Berberine Attenuates IL-1β-Induced Damage of Nucleus Pulposus Cells via Activating the AMPK/mTOR/Ulk1 Pathway
    Liaoyuan Huang et al, 2022, BioMed Research International CrossRef
43. An in‐depth analysis of the immunomodulatory mechanisms of intervertebral disc degeneration
    Chao Song et al, 2022, JOR Spine CrossRef
44. Intervertebral disc cell fate during aging and degeneration: apoptosis, senescence, and autophagy
    Takashi Yurube et al, 2023, North American Spine Society Journal (NASSJ) CrossRef
45. Current status and development direction of immunomodulatory therapy for intervertebral disk degeneration
    Yanbing Gao et al, 2023, Front. Med. CrossRef
46. Bioenergetic dysfunction in the pathogenesis of intervertebral disc degeneration
    Chao Song et al, 2024, Pharmacological Research CrossRef
47. Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKα lactylation in intervertebral disc degeneration
    Yangyang Zhang et al, 2024, Commun Biol CrossRef
48. Prognostic biomarker NRG2 correlates with autophagy and epithelial‑mesenchymal transition in breast cancer
    Ruijie Zhou et al, 2024, Oncol Lett CrossRef
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    Caichun Yue et al, 2024, American Journal of Physiology-Cell Physiology CrossRef