1. Crocin, a plant-derived carotenoid, modulates microglial reactivity
    Mücella Arikan Yorgun et al, 2017, Biochemistry and Biophysics Reports CrossRef
  2. Activation inhibitors of nuclear factor kappa B protect neurons against the NMDA-induced damage in the rat retina
    Kenji Sakamoto et al, 2017, Journal of Pharmacological Sciences CrossRef
  3. Crocin attenuates hemorrhagic shock-induced oxidative stress and organ injuries in rats
    Long Yang et al, 2017, Environmental Toxicology and Pharmacology CrossRef
  4. GRGM-13 comprising 13 plant and animal products, inhibited oxidative stress induced apoptosis in retinal ganglion cells by inhibiting P2RX7/p38 MAPK signaling pathway
    Qiu-li Zhang et al, 2018, Biomedicine & Pharmacotherapy CrossRef
  5. Crocus sativus L. stigmas and byproducts: Qualitative fingerprint, antioxidant potentials and enzyme inhibitory activities
    Luigi Menghini et al, 2018, Food Research International CrossRef
  6. Reactive Oxygen Species-Mediated Damage of Retinal Neurons: Drug Development Targets for Therapies of Chronic Neurodegeneration of the Retina
    Landon Rohowetz et al, 2018, IJMS CrossRef
  7. Antidiabetic potential of saffron and its active constituents
    Habib Yaribeygi et al, 2018, J Cell Physiol CrossRef
  8. Lycium barbarum polysaccharides alleviate hydrogen peroxide-induced injury by up-regulation of miR-4295 in human trabecular meshwork cells.
    Yuxia Liu et al, 2019, Exp Mol Pathol CrossRef
  9. Mitochondria-targeted antioxidant peptide SS-31 mediates neuroprotection in a rat experimental glaucoma model
    Xiaoqiong Wu et al, 2019 CrossRef
  10. Arbutin attenuates hydrogen peroxide-induced oxidative injury through regulation of microRNA-29a in retinal ganglion cells
    Wenbo Zhao et al, 2019, Biomedicine & Pharmacotherapy CrossRef
  11. Salidroside mitigates hydrogen peroxide-induced injury by enhancement of microRNA-27a in human trabecular meshwork cells
    Jun Zhao et al, 2019, Artificial Cells, Nanomedicine, and Biotechnology CrossRef
  12. Overexpression of CiIKKβ enhances CIK cell viability against ER stress
    Bin Zhong et al, 2019, Fish & Shellfish Immunology CrossRef
  13. Role of mammalian target of rapamycin in regulating HIF-1α and vascular endothelial growth factor signals in glaucoma
    Jinzi Zhou et al, 2019, Archives of Physiology and Biochemistry CrossRef
  14. Long-term diabetes causes molecular alterations related to fibrosis and apoptosis in rat urinary bladder
    Rania A. Elrashidy et al, 2019, Experimental and Molecular Pathology CrossRef
  15. Neuroprotection against hydrogen peroxide-induced toxicity by Dictyophora echinovolvata polysaccharide via inhibiting the mitochondria-dependent apoptotic pathway
    Wen-Xuan Yu et al, 2017, Biomedicine & Pharmacotherapy CrossRef
  16. Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Through the Activation of PI3K/Akt Signaling Pathway
    Xinguang Yang et al, 2017, J Mol Neurosci CrossRef
  17. Stability assessment of crocetin and crocetin derivatives in Gardenia yellow pigment and Gardenia fruit pomace in presence of different cooking methods
    Na Li et al, 2019, Food Chemistry CrossRef
  18. Cytoprotective effect of crocin and trans-resveratrol on photodamaged primary human retinal pigment epithelial cells
    Stefan Kassumeh et al, 2019, European Journal of Ophthalmology CrossRef
  19. Mitochondrial DNA as a Factor of Glaucomous Optic Neuropathy’s Development Mechanism
    I. R. Gazizova et al, 2019, Oftalʹmologiâ CrossRef
  20. null
    Ahmad Ghorbani, 2020 CrossRef
  21. Kaempferol Protects Against Hydrogen Peroxide-Induced Retinal Pigment Epithelium Cell Inflammation and Apoptosis by Activation of SIRT1 and Inhibition of PARP1.
    Nasser Al Sabaani, 2020, J Ocul Pharmacol Ther CrossRef
  22. Effects of saffron ( Crocus sativus L.) supplementation on inflammatory biomarkers: A systematic review and meta‐analysis
    Omid Asbaghi et al, 2020, Phytotherapy Research CrossRef
  23. The effect of crocin supplementation on lipid concentrations and fasting blood glucose: A systematic review and meta-analysis and meta-regression of randomized controlled trials
    Seyed kasra naserizadeh et al, 2020, Complementary Therapies in Medicine CrossRef
  24. Protective effect of crocin on ultraviolet B‑induced dermal fibroblast photoaging
    Mingwu Deng et al, 2018, Mol Med Report CrossRef
  25. Tetramethylpyrazine protects retinal ganglion cells against H2O2‑induced damage via the�microRNA‑182/mitochondrial pathway
    Xinmin Li et al, 2019, Int J Mol Med CrossRef
  26. Gadd45α affects retinal ganglion cell injury in chronic ocular hypertension rats by regulating p38MAPK pathway.
    Rui-Xue Sun et al, 2020, Gene CrossRef
  27. Novel Neuroprotective Potential of Crocin in Neurodegenerative Disorders: An Illustrated Mechanistic Review
    Sareh Kermanshahi et al, 2020, Neurochem Res CrossRef
  28. Effect of dietary modification and antioxidant supplementation on intraocular pressure and open-angle glaucoma
    Sayena Jabbehdari et al, 2020, European Journal of Ophthalmology CrossRef
  29. Inhibition of protein kinase R by C16 protects the retinal ganglion cells from hypoxia-induced oxidative stress, inflammation, and apoptosis
    Nasser Al Sabaani, 2020, Current Eye Research CrossRef
  30. Extraction optimization by using response surface methodology and purification of yellow pigment from Gardenia jasminoides var. radicans Makikno
    Jun Wu et al, 2020, Food Sci Nutr CrossRef
  31. Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma
    Joao N. Duarte et al, 2021, Journal of Ophthalmology CrossRef
  32. Scale-Up Preparation of Crocins I and II from Gardeniajasminoides by a Two-Step Chromatographic Approach and Their Inhibitory Activity Against ATP Citrate Lyase
    Shuguang Guan et al, 2021, Molecules CrossRef
  33. The therapeutic potential of Crocus sativus Linn.: A comprehensive narrative review of clinical trials
    Neda Roshanravan et al, 2021, Phytotherapy Research CrossRef
  34. Polydopamine nanoparticles attenuate retina ganglion cell degeneration and restore visual function after optic nerve injury
    Xiaotong Lou et al, 2021, J Nanobiotechnol CrossRef
  35. Treatment of Glaucoma with Natural Products and Their Mechanism of Action: An Update
    Ru Hui Sim et al, 2022, Nutrients CrossRef
  36. Crocin as a vision supplement
    Mojtaba Heydari et al, 2022, Clinical and Experimental Optometry CrossRef
  37. The Functional Vision Restorative Effect of Crocin via the BDNF–TrkB Pathway: An In Vivo Study
    Jia-Lain Wu et al, 2022, Nutrients CrossRef
  38. The Intertwined Roles of Oxidative Stress and Endoplasmic Reticulum Stress in Glaucoma
    Daire John Hurley et al, 2022, Antioxidants CrossRef
  39. Pharmacological Effects of Saffron and its Constituents in Ocular Disorders from in vitro Studies to Clinical Trials: A Systematic Review
    Samaneh Sepahi et al, 2021, CN CrossRef
  40. Saffron and retinal neurodegenerative diseases: Relevance of chemical composition
    Maria A. Maggi et al, 2022, Journal of Anatomy CrossRef
  41. Crocin molecular signaling pathways at a glance: A comprehensive review
    Motahareh Boozari et al, 2022, Phytotherapy Research CrossRef
  42. Crocin Attenuates NLRP3 Inflammasome Activation by Inhibiting Mitochondrial Reactive Oxygen Species and Ameliorates Monosodium Urate-Induced Mouse Peritonitis
    Ruth Sangare et al, 2023, CIMB CrossRef
  43. Crocin supplementation in primary open angle glaucoma: a randomized, triple-blind, placebo-controlled clinical trial
    Sina Mahdiani et al, 2023, Medicine in Drug Discovery CrossRef
  44. Mucoadhesive liposomal delivery system synergizing anti-inflammation and anti-oxidation for enhanced treatment against dry eye disease
    Kexin Huang et al, 2024, Journal of Controlled Release CrossRef