- BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes
Chang-Nim Im et al, 2016, Oncotarget CrossRef - Multiple regulation pathways and pivotal biological functions of STAT3 in cancer
Jie Yuan et al, 2015, Scientific Reports CrossRef - PIM1 Inhibition Affects Glioblastoma Stem Cell Behavior and Kills Glioblastoma Stem-like Cells
Carolin Seifert et al, 2021, International Journal of Molecular Sciences CrossRef - Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells
Subbroto Kumar Saha et al, 2018, International Journal of Molecular Sciences CrossRef - The role of STAT3 in glioblastoma progression through dual influences on tumor cells and the immune microenvironment
Nakho Chang et al, 2017, Molecular and Cellular Endocrinology CrossRef - miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis
Liu Qingjuan et al, 2016, American Journal of Physiology-Cell Physiology CrossRef - Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds
A.R.M. Ruhul Amin et al, 2015, Seminars in Cancer Biology CrossRef - The roles of FOXM1 in pancreatic stem cells and carcinogenesis
Ming Quan et al, 2013, Molecular Cancer CrossRef - Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extract, Silymarin, and Silibinin via Modulation of Oxidative Stress, Apoptosis, Nrf2, PPARγ, NF‐κB, and PI3K/Akt Signaling Pathways
Nour Y. S. Yassin et al, 2021, Oxidative Medicine and Cellular Longevity CrossRef - Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer
Naohide Oue et al, 2018, Pathobiology CrossRef - Roles of PTEN (Phosphatase and Tensin Homolog) in Gastric Cancer Development and Progression
Wen-Ting Xu et al, 2014, Asian Pacific Journal of Cancer Prevention CrossRef - α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of Stat3 signaling pathway
Tao Shan et al, 2014, Acta Pharmacologica Sinica CrossRef - STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer
Julia E Lefler et al, 2022, Life Science Alliance CrossRef - Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28
Jiang Xu et al, 2021, Journal of Bone Oncology CrossRef - Identification of the Prognostic Signatures of Glioma With Different PTEN Status
Pei Zhang et al, 2021, Frontiers in Oncology CrossRef - Role of PI3K/AKT Signaling Pathway in Proliferation, Migration and Odontogenic Differentiation of Human Dental Pulp Stem Cells
Fang Zhang et al, 2020, Journal of Hard Tissue Biology CrossRef - A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas
Yukiko Nakahara et al, 2022, Brain Sciences CrossRef - NLRP3 in human glioma is correlated with increased WHO grade, and regulates cellular proliferation, apoptosis and metastasis via epithelial-mesenchymal transition and the PTEN/AKT signaling pathway
Xiao-Feng Yin et al, 2018, International Journal of Oncology CrossRef - Fucoxanthin induces apoptosis in human cervical cancer cell line HeLa via PI3K/Akt pathway
Guoliu Ye et al, 2014, Tumor Biology CrossRef - Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression
S. J. Kim et al, 2019, Oncogene CrossRef - PTEN in cancer associated fibroblasts
Julia E. Lefler et al, 2022, Stromal Signaling in Cancer CrossRef - Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome
Konstantin Masliantsev et al, 2018, Oncotarget CrossRef - Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer
Xinran Li et al, 2019, Nature Communications CrossRef - Functional and Molecular Characters of Cancer Stem Cells Through Development to Establishment
Said M. Afify et al, 2022, Cancer Stem Cell Markers and Related Network Pathways CrossRef - Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer
Chitra Joseph et al, 2019, Breast Cancer Research and Treatment CrossRef - Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma
Nicholas Eustace et al, 2019, International Journal of Oncology CrossRef - Interleukin 6 and cancer resistance in glioblastoma multiforme
Donald Detchou et al, 2024, Neurosurgical Review CrossRef - USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells In Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
Yue Gao et al, SSRN Electronic Journal CrossRef - Selective FGFR inhibitor BGJ398 inhibits phosphorylation of AKT and STAT3 and induces cytotoxicity in sphere-cultured ovarian cancer cells
Hwa Jun Cha et al, 2017, International Journal of Oncology CrossRef - Ginseng polysaccharide promotes the apoptosis of colon cancer cells via activating the NLRP3 inflammasome
Xiaoyan Tian et al, 2024, Immunopharmacology and Immunotoxicology CrossRef - PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer
Michele Milella et al, 2017, Scientific Reports CrossRef - Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasion, migration and epithelial‑mesenchymal transition of glioma by regulating PTEN/PI3K/AKT signaling via binding to N‑myc downstream regulated gene 1 promoter
Jing Zhang et al, 2021, International Journal of Molecular Medicine CrossRef - Activation of peroxisome proliferator-activated receptor γ ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
XINMING XIE et al, 2015, Biomedical Reports CrossRef - MicroRNA-214 acts as a potential oncogene in breast cancer by targeting the PTEN-PI3K/Akt signaling pathway
FANG WANG et al, 2016, International Journal of Molecular Medicine CrossRef - Targeting the molecular mechanisms of glioma stem cell resistance to chemotherapy
Jawad Fares et al, 2021, Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies CrossRef - STAT3, stem cells, cancer stem cells and p63
Michaela Galoczova et al, 2018, Cellular & Molecular Biology Letters CrossRef - Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal
Fabrizio Marcucci et al, 2016, Frontiers in Oncology CrossRef - KRT19 directly interacts with β-catenin/RAC1 complex to regulate NUMB-dependent NOTCH signaling pathway and breast cancer properties
S K Saha et al, 2017, Oncogene CrossRef - Multi-Omics Identification of Genetic Alterations in Head and Neck Squamous Cell Carcinoma and Therapeutic Efficacy of HNC018 as a Novel Multi-Target Agent for c-MET/STAT3/AKT Signaling Axis
Harshita Nivrutti Khedkar et al, 2023, International Journal of Molecular Sciences CrossRef - The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-κB/cyclin D1 pathway in mouse mesangial cells
Xiao-Juan Feng et al, 2014, American Journal of Physiology-Cell Physiology CrossRef - Combined Inhibition of HDAC and EGFR Reduces Viability and Proliferation and Enhances STAT3 mRNA Expression in Glioblastoma Cells
Marienela Buendia Duque et al, 2019, Journal of Molecular Neuroscience CrossRef - Biomimetic models to examine microenvironmental regulation of glioblastoma stem cells
Pinaki S. Nakod et al, 2018, Cancer Letters CrossRef - Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation
Yaqiong Tian et al, 2019, Aging Cell CrossRef - PP2 suppresses proliferation and migration of C6 Glioma and MDA-MB-231 cells by targeting both fibroblast growth factor receptor 1 and Src
Yanyan Yang et al, 2024, Chemico-Biological Interactions CrossRef - Mechanisms of cancer stem cell senescence: Current understanding and future perspectives
Da‐Yong Zhang et al, 2021, Clinical and Experimental Pharmacology and Physiology CrossRef - PIWI family emerging as a decisive factor of cell fate: An overview
Murugavel Ponnusamy et al, 2017, European Journal of Cell Biology CrossRef - ERBB Signaling Pathway in Cancer Stem Cells
Ghmkin Hassan et al, 2022, Cancer Stem Cell Markers and Related Network Pathways CrossRef - Morusin Induces TRAIL Sensitization by Regulating EGFR and DR5 in Human Glioblastoma Cells
Dain Park et al, 2016, Journal of Natural Products CrossRef - C6 glioma-conditioned medium induces malignant transformation of mesenchymal stem cells: Possible role of S100B/RAGE pathway
Bin Tan et al, 2018, Biochemical and Biophysical Research Communications CrossRef - CCR7 Regulates Cell Migration and Invasion through JAK2/STAT3 in Metastatic Squamous Cell Carcinoma of the Head and Neck
Fa-Yu Liu et al, 2014, BioMed Research International CrossRef - MiR-200a acts as an oncogene in colorectal carcinoma by targeting PTEN
Yijun Li et al, 2016, Experimental and Molecular Pathology CrossRef - Melittin Restores PTEN Expression by Down-Regulating HDAC2 in Human Hepatocelluar Carcinoma HepG2 Cells
Hui Zhang et al, 2014, PLoS ONE CrossRef - Biological and clinical significance of cancer stem cell plasticity
Yongyou Zhu et al, 2014, Clinical and Translational Medicine CrossRef - Identification of Secreted Phosphoprotein 1 (SPP1) as a Prognostic Factor in Lower-Grade Gliomas
Jiawei Chen et al, 2019, World Neurosurgery CrossRef - Pten Regulates Development and Lactation in the Mammary Glands of Dairy Cows
Zhuoran Wang et al, 2014, PLoS ONE CrossRef - Ipilimumab, Pembrolizumab, or Nivolumab in Combination with BBI608 in Patients with Advanced Cancers Treated at MD Anderson Cancer Center
Henry Hiep Vo et al, 2022, Cancers CrossRef - Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation
Liang Lu et al, 2017, Cell Death & Disease CrossRef - PTEN drives Th17 cell differentiation by preventing IL-2 production
Hyeong Su Kim et al, 2017, Journal of Experimental Medicine CrossRef - IL‐1β promotes the nuclear translocaiton of S100A4 protein in gastric cancer cells MGC803 and the cell's stem‐like properties through PI3K pathway
Aiwen Yu et al, 2018, Journal of Cellular Biochemistry CrossRef - Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer
Xiaowei Zhang et al, 2016, Oncotarget CrossRef - Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment
Byung-Hak Kim et al, 2016, Archives of Pharmacal Research CrossRef - A microRNA signature profile in EBV+ diffuse large B-cell lymphoma of the elderly
Tathiana Azevedo de Andrade et al, 2014, Oncotarget CrossRef - MicroRNA-106b promotes pituitary tumor cell proliferation and invasion through PI3K/AKT signaling pathway by targeting PTEN
Kai Zhou et al, 2016, Tumor Biology CrossRef - USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
Yue Gao et al, 2021, Frontiers in Cell and Developmental Biology CrossRef - Emerging trends and research foci of epithelial–mesenchymal transition in gliomas: A scientometric analysis and review
Yang Xing et al, 2022, Frontiers in Oncology CrossRef - Reduced expression levels of PTEN are associated with decreased sensitivity of HCC827 cells to icotinib
Yang Zhai et al, 2017, Oncology Letters CrossRef - An IKK/NF-κB Activation/p53 Deletion Sequence Drives Liver Carcinogenesis and Tumor Differentiation
Michael Svinarenko et al, 2019, Cancers CrossRef - Microcystin-LR promotes migration via the cooperation between microRNA-221/PTEN and STAT3 signal pathway in colon cancer cell line DLD-1
Yan Ren et al, 2019, Ecotoxicology and Environmental Safety CrossRef - Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
Mehrdad Hashemi et al, 2023, Biomedicine & Pharmacotherapy CrossRef - MiR-202-5p/PTEN mediates doxorubicin-resistance of breast cancer cells via PI3K/Akt signaling pathway
Tao Liu et al, 2019, Cancer Biology & Therapy CrossRef - 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway
Kyung-Ran Park et al, 2016, Oncotarget CrossRef - MicroRNA miR-100 Decreases Glioblastoma Growth by Targeting SMARCA5 and ErbB3 in Tumor-Initiating Cells
Bahauddeen M. Alrfaei et al, 2020, Technology in Cancer Research & Treatment CrossRef - Silencing of RegIV by shRNA causes the loss of stemness properties of cancer stem cells in MKN45 gastric cancer cells
WEI ZHOU et al, 2013, Oncology Reports CrossRef - Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway
Mingdi Zhang et al, 2017, Tumor Biology CrossRef - Signaling pathways governing glioma cancer stem cells behavior
Ava Nasrolahi et al, 2023, Cellular Signalling CrossRef - miRNA‐216 knockdown has effects to suppress osteosarcoma via stimulating PTEN
Ping Jiang et al, 2020, Food Science & Nutrition CrossRef - The emerging role of tumor-suppressive microRNA-218 in targeting glioblastoma stemness
Xingchun Gao et al, 2014, Cancer Letters CrossRef