1. BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes
    Chang-Nim Im et al, 2016, Oncotarget CrossRef
  2. Multiple regulation pathways and pivotal biological functions of STAT3 in cancer
    Jie Yuan et al, 2015, Scientific Reports CrossRef
  3. PIM1 Inhibition Affects Glioblastoma Stem Cell Behavior and Kills Glioblastoma Stem-like Cells
    Carolin Seifert et al, 2021, International Journal of Molecular Sciences CrossRef
  4. Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells
    Subbroto Kumar Saha et al, 2018, International Journal of Molecular Sciences CrossRef
  5. The role of STAT3 in glioblastoma progression through dual influences on tumor cells and the immune microenvironment
    Nakho Chang et al, 2017, Molecular and Cellular Endocrinology CrossRef
  6. miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis
    Liu Qingjuan et al, 2016, American Journal of Physiology-Cell Physiology CrossRef
  7. Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds
    A.R.M. Ruhul Amin et al, 2015, Seminars in Cancer Biology CrossRef
  8. The roles of FOXM1 in pancreatic stem cells and carcinogenesis
    Ming Quan et al, 2013, Molecular Cancer CrossRef
  9. Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extract, Silymarin, and Silibinin via Modulation of Oxidative Stress, Apoptosis, Nrf2, PPARγ, NF‐κB, and PI3K/Akt Signaling Pathways
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  10. Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer
    Naohide Oue et al, 2018, Pathobiology CrossRef
  11. Roles of PTEN (Phosphatase and Tensin Homolog) in Gastric Cancer Development and Progression
    Wen-Ting Xu et al, 2014, Asian Pacific Journal of Cancer Prevention CrossRef
  12. α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of Stat3 signaling pathway
    Tao Shan et al, 2014, Acta Pharmacologica Sinica CrossRef
  13. STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer
    Julia E Lefler et al, 2022, Life Science Alliance CrossRef
  14. Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28
    Jiang Xu et al, 2021, Journal of Bone Oncology CrossRef
  15. Identification of the Prognostic Signatures of Glioma With Different PTEN Status
    Pei Zhang et al, 2021, Frontiers in Oncology CrossRef
  16. Role of PI3K/AKT Signaling Pathway in Proliferation, Migration and Odontogenic Differentiation of Human Dental Pulp Stem Cells
    Fang Zhang et al, 2020, Journal of Hard Tissue Biology CrossRef
  17. A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas
    Yukiko Nakahara et al, 2022, Brain Sciences CrossRef
  18. NLRP3 in human glioma is correlated with increased WHO grade, and regulates cellular proliferation, apoptosis and metastasis via epithelial-mesenchymal transition and the PTEN/AKT signaling pathway
    Xiao-Feng Yin et al, 2018, International Journal of Oncology CrossRef
  19. Fucoxanthin induces apoptosis in human cervical cancer cell line HeLa via PI3K/Akt pathway
    Guoliu Ye et al, 2014, Tumor Biology CrossRef
  20. Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression
    S. J. Kim et al, 2019, Oncogene CrossRef
  21. PTEN in cancer associated fibroblasts
    Julia E. Lefler et al, 2022, Stromal Signaling in Cancer CrossRef
  22. Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome
    Konstantin Masliantsev et al, 2018, Oncotarget CrossRef
  23. Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer
    Xinran Li et al, 2019, Nature Communications CrossRef
  24. Functional and Molecular Characters of Cancer Stem Cells Through Development to Establishment
    Said M. Afify et al, 2022, Cancer Stem Cell Markers and Related Network Pathways CrossRef
  25. Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer
    Chitra Joseph et al, 2019, Breast Cancer Research and Treatment CrossRef
  26. Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma
    Nicholas Eustace et al, 2019, International Journal of Oncology CrossRef
  27. Interleukin 6 and cancer resistance in glioblastoma multiforme
    Donald Detchou et al, 2024, Neurosurgical Review CrossRef
  28. USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells In Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
    Yue Gao et al, SSRN Electronic Journal CrossRef
  29. Selective FGFR inhibitor BGJ398 inhibits phosphorylation of AKT and STAT3 and induces cytotoxicity in sphere-cultured ovarian cancer cells
    Hwa Jun Cha et al, 2017, International Journal of Oncology CrossRef
  30. Ginseng polysaccharide promotes the apoptosis of colon cancer cells via activating the NLRP3 inflammasome
    Xiaoyan Tian et al, 2024, Immunopharmacology and Immunotoxicology CrossRef
  31. PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer
    Michele Milella et al, 2017, Scientific Reports CrossRef
  32. Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasion, migration and epithelial‑mesenchymal transition of glioma by regulating PTEN/PI3K/AKT signaling via binding to N‑myc downstream regulated gene 1 promoter
    Jing Zhang et al, 2021, International Journal of Molecular Medicine CrossRef
  33. Activation of peroxisome proliferator-activated receptor γ ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
    XINMING XIE et al, 2015, Biomedical Reports CrossRef
  34. MicroRNA-214 acts as a potential oncogene in breast cancer by targeting the PTEN-PI3K/Akt signaling pathway
    FANG WANG et al, 2016, International Journal of Molecular Medicine CrossRef
  35. Targeting the molecular mechanisms of glioma stem cell resistance to chemotherapy
    Jawad Fares et al, 2021, Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies CrossRef
  36. STAT3, stem cells, cancer stem cells and p63
    Michaela Galoczova et al, 2018, Cellular & Molecular Biology Letters CrossRef
  37. Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal
    Fabrizio Marcucci et al, 2016, Frontiers in Oncology CrossRef
  38. KRT19 directly interacts with β-catenin/RAC1 complex to regulate NUMB-dependent NOTCH signaling pathway and breast cancer properties
    S K Saha et al, 2017, Oncogene CrossRef
  39. Multi-Omics Identification of Genetic Alterations in Head and Neck Squamous Cell Carcinoma and Therapeutic Efficacy of HNC018 as a Novel Multi-Target Agent for c-MET/STAT3/AKT Signaling Axis
    Harshita Nivrutti Khedkar et al, 2023, International Journal of Molecular Sciences CrossRef
  40. The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-κB/cyclin D1 pathway in mouse mesangial cells
    Xiao-Juan Feng et al, 2014, American Journal of Physiology-Cell Physiology CrossRef
  41. Combined Inhibition of HDAC and EGFR Reduces Viability and Proliferation and Enhances STAT3 mRNA Expression in Glioblastoma Cells
    Marienela Buendia Duque et al, 2019, Journal of Molecular Neuroscience CrossRef
  42. Biomimetic models to examine microenvironmental regulation of glioblastoma stem cells
    Pinaki S. Nakod et al, 2018, Cancer Letters CrossRef
  43. Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation
    Yaqiong Tian et al, 2019, Aging Cell CrossRef
  44. PP2 suppresses proliferation and migration of C6 Glioma and MDA-MB-231 cells by targeting both fibroblast growth factor receptor 1 and Src
    Yanyan Yang et al, 2024, Chemico-Biological Interactions CrossRef
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    Da‐Yong Zhang et al, 2021, Clinical and Experimental Pharmacology and Physiology CrossRef
  46. PIWI family emerging as a decisive factor of cell fate: An overview
    Murugavel Ponnusamy et al, 2017, European Journal of Cell Biology CrossRef
  47. ERBB Signaling Pathway in Cancer Stem Cells
    Ghmkin Hassan et al, 2022, Cancer Stem Cell Markers and Related Network Pathways CrossRef
  48. Morusin Induces TRAIL Sensitization by Regulating EGFR and DR5 in Human Glioblastoma Cells
    Dain Park et al, 2016, Journal of Natural Products CrossRef
  49. C6 glioma-conditioned medium induces malignant transformation of mesenchymal stem cells: Possible role of S100B/RAGE pathway
    Bin Tan et al, 2018, Biochemical and Biophysical Research Communications CrossRef
  50. CCR7 Regulates Cell Migration and Invasion through JAK2/STAT3 in Metastatic Squamous Cell Carcinoma of the Head and Neck
    Fa-Yu Liu et al, 2014, BioMed Research International CrossRef
  51. MiR-200a acts as an oncogene in colorectal carcinoma by targeting PTEN
    Yijun Li et al, 2016, Experimental and Molecular Pathology CrossRef
  52. Melittin Restores PTEN Expression by Down-Regulating HDAC2 in Human Hepatocelluar Carcinoma HepG2 Cells
    Hui Zhang et al, 2014, PLoS ONE CrossRef
  53. Biological and clinical significance of cancer stem cell plasticity
    Yongyou Zhu et al, 2014, Clinical and Translational Medicine CrossRef
  54. Identification of Secreted Phosphoprotein 1 (SPP1) as a Prognostic Factor in Lower-Grade Gliomas
    Jiawei Chen et al, 2019, World Neurosurgery CrossRef
  55. Pten Regulates Development and Lactation in the Mammary Glands of Dairy Cows
    Zhuoran Wang et al, 2014, PLoS ONE CrossRef
  56. Ipilimumab, Pembrolizumab, or Nivolumab in Combination with BBI608 in Patients with Advanced Cancers Treated at MD Anderson Cancer Center
    Henry Hiep Vo et al, 2022, Cancers CrossRef
  57. Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation
    Liang Lu et al, 2017, Cell Death & Disease CrossRef
  58. PTEN drives Th17 cell differentiation by preventing IL-2 production
    Hyeong Su Kim et al, 2017, Journal of Experimental Medicine CrossRef
  59. IL‐1β promotes the nuclear translocaiton of S100A4 protein in gastric cancer cells MGC803 and the cell's stem‐like properties through PI3K pathway
    Aiwen Yu et al, 2018, Journal of Cellular Biochemistry CrossRef
  60. Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer
    Xiaowei Zhang et al, 2016, Oncotarget CrossRef
  61. Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment
    Byung-Hak Kim et al, 2016, Archives of Pharmacal Research CrossRef
  62. A microRNA signature profile in EBV+ diffuse large B-cell lymphoma of the elderly
    Tathiana Azevedo de Andrade et al, 2014, Oncotarget CrossRef
  63. MicroRNA-106b promotes pituitary tumor cell proliferation and invasion through PI3K/AKT signaling pathway by targeting PTEN
    Kai Zhou et al, 2016, Tumor Biology CrossRef
  64. USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
    Yue Gao et al, 2021, Frontiers in Cell and Developmental Biology CrossRef
  65. Emerging trends and research foci of epithelial–mesenchymal transition in gliomas: A scientometric analysis and review
    Yang Xing et al, 2022, Frontiers in Oncology CrossRef
  66. Reduced expression levels of PTEN are associated with decreased sensitivity of HCC827 cells to icotinib
    Yang Zhai et al, 2017, Oncology Letters CrossRef
  67. An IKK/NF-κB Activation/p53 Deletion Sequence Drives Liver Carcinogenesis and Tumor Differentiation
    Michael Svinarenko et al, 2019, Cancers CrossRef
  68. Microcystin-LR promotes migration via the cooperation between microRNA-221/PTEN and STAT3 signal pathway in colon cancer cell line DLD-1
    Yan Ren et al, 2019, Ecotoxicology and Environmental Safety CrossRef
  69. Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
    Mehrdad Hashemi et al, 2023, Biomedicine & Pharmacotherapy CrossRef
  70. MiR-202-5p/PTEN mediates doxorubicin-resistance of breast cancer cells via PI3K/Akt signaling pathway
    Tao Liu et al, 2019, Cancer Biology & Therapy CrossRef
  71. 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway
    Kyung-Ran Park et al, 2016, Oncotarget CrossRef
  72. MicroRNA miR-100 Decreases Glioblastoma Growth by Targeting SMARCA5 and ErbB3 in Tumor-Initiating Cells
    Bahauddeen M. Alrfaei et al, 2020, Technology in Cancer Research & Treatment CrossRef
  73. Silencing of RegIV by shRNA causes the loss of stemness properties of cancer stem cells in MKN45 gastric cancer cells
    WEI ZHOU et al, 2013, Oncology Reports CrossRef
  74. Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway
    Mingdi Zhang et al, 2017, Tumor Biology CrossRef
  75. Signaling pathways governing glioma cancer stem cells behavior
    Ava Nasrolahi et al, 2023, Cellular Signalling CrossRef
  76. miRNA‐216 knockdown has effects to suppress osteosarcoma via stimulating PTEN
    Ping Jiang et al, 2020, Food Science & Nutrition CrossRef
  77. The emerging role of tumor-suppressive microRNA-218 in targeting glioblastoma stemness
    Xingchun Gao et al, 2014, Cancer Letters CrossRef