1. Resveratrol Inhibits the TGF-β1-Induced Proliferation of Cardiac Fibroblasts and Collagen Secretion by Downregulating miR-17 in Rat
    Yao Zhang et al, 2018, BioMed Research International CrossRef
  2. Effect of Fibroblast Growth Factor 21 on the Expression of TLR4 and BAMBI Genes in Cholesterol-Treated Human Hepatic Stellate Cells
    Elham Shakerian et al, 2021, Jentashapir Journal of Cellular and Molecular Biology CrossRef
  3. Microarray Study of Pathway Analysis Expression Profile Associated with MicroRNA-29a with Regard to Murine Cholestatic Liver Injuries
    Sung-Chou Li et al, 2016, International Journal of Molecular Sciences CrossRef
  4. miR-4286/TGF-β1/Smad3-Negative Feedback Loop Ameliorated Vascular Endothelial Cell Damage by Attenuating Apoptosis and Inflammatory Response
    Zhiyu He et al, 2020, Journal of Cardiovascular Pharmacology CrossRef
  5. MiR-15b and miR-16 suppress TGF-β1-induced proliferation and fibrogenesis by regulating LOXL1 in hepatic stellate cells
    Li Ma et al, 2021, Life Sciences CrossRef
  6. The effect of saraglitazar on TGF-β-induced smad3 phosphorylation and expression of genes related to liver fibrosis in LX2 cell line
    Negar Dinarvand et al, 2024, Molecular Biology Reports CrossRef
  7. Insulin-like growth factor binding protein-4 exerts antifibrotic activity by reducing levels of connective tissue growth factor and the C-X-C chemokine receptor 4
    YunYun Su et al, 2019, FASEB BioAdvances CrossRef
  8. CXXC5 suppresses hepatocellular carcinoma by promoting TGF-β-induced cell cycle arrest and apoptosis
    Xiaohua Yan et al, 2018, Journal of Molecular Cell Biology CrossRef
  9. MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice
    Ya-Ling Yang et al, 2019, International Journal of Molecular Sciences CrossRef
  10. The role of oxymatrine in regulating TGF-β1 in rats with hepatic fibrosis
    Jing Wu et al, 2018, Acta Cirurgica Brasileira CrossRef
  11. BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2
    Rosemary A. Bayne et al, 2016, Molecular Human Reproduction CrossRef
  12. Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs
    Chen Chen et al, 2020, Bone Research CrossRef
  13. Diabetes complications and extracellular vesicle therapy
    Setareh Soltani et al, 2022, Reviews in Endocrine and Metabolic Disorders CrossRef
  14. A High-Salt Diet Exacerbates Liver Fibrosis through Enterococcus -Dependent Macrophage Activation
    Xujun Zhang et al, 2023, Microbiology Spectrum CrossRef
  15. Cells, cytokines, and factors involved in profibrogenic pathways
    Pablo Muriel, 2022, Hepatic Fibrosis CrossRef
  16. Deletion of Smad4 reduces hepatic inflammation and fibrogenesis during nonalcoholic steatohepatitis progression
    Geng Qin et al, 2018, Journal of Digestive Diseases CrossRef
  17. Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor
    Dong-Jing Yang et al, 2021, Scientific Reports CrossRef
  18. ADAM and ADAMTS Proteins, New Players in the Regulation of Hepatocellular Carcinoma Microenvironment
    Nathalie Théret et al, 2021, Cancers CrossRef
  19. Identification and integrative analysis of microRNAs and mRNAs involved in proliferation and invasion of pressure‑treated human liver cancer cell lines
    Si Shen et al, 2019, Molecular Medicine Reports CrossRef
  20. Modeling of DNA Damage Repair and Cell Response in Relation to p53 System Exposed to Ionizing Radiation
    Ankang Hu et al, 2022, International Journal of Molecular Sciences CrossRef
  21. Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease
    Joanne E. Murphy-Ullrich et al, 2018, Matrix Biology CrossRef
  22. Artificial MicroRNA-MediatedTgfbr2andPdgfrbCo-Silencing Ameliorates Carbon Tetrachloride–Induced Hepatic Fibrosis in Mice
    Yan Jiang et al, 2019, Human Gene Therapy CrossRef
  23. Obeticholic acid prevents carbon tetrachloride-induced liver fibrosis through interaction between farnesoid X receptor and Smad3
    Yuan-Yuan Fan et al, 2019, International Immunopharmacology CrossRef
  24. Depletion of serotonin relieves concanavalin A-induced liver fibrosis in mice by inhibiting inflammation, oxidative stress, and TGF-β1/Smads signaling pathway
    Qing Pang et al, 2021, Toxicology Letters CrossRef
  25. Activation of corticotropin releasing factor receptors up regulates collagen production by hepatic stellate cells via promoting p300 expression
    Changzhen Wang et al, 2016, Biological Chemistry CrossRef
  26. Elastin Fiber Accumulation in Liver Correlates with the Development of Hepatocellular Carcinoma
    Yutaka Yasui et al, 2016, PLOS ONE CrossRef
  27. Participation of the SMAD2/3 signalling pathway in the down regulation of megalin/LRP2 by transforming growth factor beta (TGF-ß1)
    Felipe Cabezas et al, 2019, PLOS ONE CrossRef
  28. TGF‐β signalling and liver disease
    Isabel Fabregat et al, 2016, The FEBS Journal CrossRef
  29. Fibroblast Growth Factor 21 Reduces Cholesterol-Induced Hepatic Fibrogenesis by Inhibiting TGF-β/Smad3C Signaling Pathway in LX2 Cells
    Reza Afarin et al, 2021, Hepatitis Monthly CrossRef
  30. Viral hepatitis and hepatocellular carcinoma: From molecular pathways to the role of clinical surveillance and antiviral treatment
    Leonardo Stella et al, 2022, World Journal of Gastroenterology CrossRef
  31. Tumor Stroma, Desmoplasia, and Stromagenesis
    Arthur Zimmermann, 2016, Tumors and Tumor-Like Lesions of the Hepatobiliary Tract CrossRef
  32. Glucocorticoids Have Opposing Effects on Liver Fibrosis in Hepatic Stellate and Immune Cells
    Kang Ho Kim et al, 2016, Molecular Endocrinology CrossRef
  33. Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocellular carcinoma progression via miR-145/miR-21 mediated Smad3 phosphorylation
    Chao Wu et al, 2019, Journal of Ethnopharmacology CrossRef
  34. Targeting Extracellular Cyclophilins Ameliorates Disease Progression in Experimental Biliary Atresia
    Tatiana Iordanskaia et al, 2015, Molecular Medicine CrossRef
  35. MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells
    A. Boye et al, 2015, Tumor Biology CrossRef
  36. Platyconic Acid A, Platycodi Radix-Derived Saponin, Suppresses TGF-β1-Induced Activation of Hepatic Stellate Cells via Blocking SMAD and Activating the PPARγ Signaling Pathway
    Jae Ho Choi et al, 2019, Cells CrossRef
  37. CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-β-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
    Runzhou Zhuang et al, 2017, Oncotarget CrossRef
  38. Interference of lysine-specific demethylase 1 inhibits cellular invasion and proliferation in vivo in gastric cancer MKN-28 cells
    Yan Li et al, 2016, Biomedicine & Pharmacotherapy CrossRef
  39. Prevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model
    Lunjie Lu et al, 2016, Evidence-Based Complementary and Alternative Medicine CrossRef
  40. Palmitoylethanolamide Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Rats
    Masatsugu Ohara et al, 2018, Frontiers in Pharmacology CrossRef
  41. Transcriptomic Study on Ovine Immune Responses to Fasciola hepatica Infection
    Yan Fu et al, 2016, PLOS Neglected Tropical Diseases CrossRef
  42. Role of microRNA-363 during tumor progression and invasion
    Arya Nasimi Shad et al, 2024, Journal of Physiology and Biochemistry CrossRef
  43. Increased risk of malignancy in patients with an aortic aneurysm: a nationwide population-based retrospective study
    Jen-Chun Wang et al, 2018, Oncotarget CrossRef
  44. Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway
    Li-Ying Song et al, 2019, BMC Complementary and Alternative Medicine CrossRef
  45. Integrated Computational Model of Intracellular Signaling and microRNA Regulation Predicts the Network Balances and Timing Constraints Critical to the Hepatic Stellate Cell Activation Process
    Lakshmi Kuttippurathu et al, 2014, Processes CrossRef
  46. Lepidium sativum Secondary Metabolites (Essential Oils): In Vitro and In Silico Studies on Human Hepatocellular Carcinoma Cell Lines
    Shaimaa Nazir et al, 2021, Plants CrossRef
  47. Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a
    Wenjing Lei et al, 2015, PLOS ONE CrossRef
  48. Buckwheat Treatment Ameliorates Transforming Growth Factor Beta-1, its Receptor Gene Expression and Biochemical Parameters in Experimental Steatohepatitis
    Sahar Y. Al-Okbi et al, 2018, International Journal of Botany CrossRef
  49. mRNA-miRNA-lncRNA Regulatory Network in Nonalcoholic Fatty Liver Disease
    Marwa Matboli et al, 2021, International Journal of Molecular Sciences CrossRef
  50. Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-β1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis — A review
    Yongfang Gong et al, 2020, Life Sciences CrossRef
  51. Anti-hepatic fibrosis effects of a novel turtle shell decoction by inhibiting hepatic stellate cell proliferation and blocking TGF-β1/Smad signaling pathway in rats
    Ganping Bai et al, 2016, Oncology Reports CrossRef
  52. miR‑127 aggravates myocardial failure by promoting the TGF‑β1/Smad3 signaling
    Hainian Xu et al, 2018, Molecular Medicine Reports CrossRef
  53. Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation
    Yuping Zhou et al, 2016, Journal of Ethnopharmacology CrossRef
  54. The rationale for targeting TGF‐β in chronic liver diseases
    Gianluigi Giannelli et al, 2016, European Journal of Clinical Investigation CrossRef
  55. Screening for and validation of a hepatic fibrosis-related pathway induced by insulin-like growth factor-binding protein-related protein 1
    XiaoHong Guo et al, 2016, European Journal of Gastroenterology & Hepatology CrossRef
  56. BMP signalling: agony and antagony in the family
    Derek P. Brazil et al, 2015, Trends in Cell Biology CrossRef
  57. Tolerability and Pharmacokinetics of Hydronidone, an Antifibrotic Agent for Hepatic Fibrosis, after Single and Multiple Doses in Healthy Subjects: an Open-Label, Randomized, Dose-Escalating, First-in-Human Study
    Yani Liu et al, 2017, European Journal of Drug Metabolism and Pharmacokinetics CrossRef
  58. Precancerous niche (PCN), a product of fibrosis with remodeling by incessant chronic inflammation
    Björn L.D.M. Brücher et al, 2019, 4open CrossRef
  59. Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF‐β/Smad Signaling Pathway
    Guang Xu et al, 2024, Analytical Cellular Pathology CrossRef
  60. Hepatocellular Carcinoma Metastasis and Circulating Tumor Cells
    Kien Pham et al, 2018, Precision Molecular Pathology of Liver Cancer CrossRef
  61. MicroRNA-195 Activates Hepatic Stellate Cells In Vitro by Targeting Smad7
    Li-Ying Song et al, 2017, BioMed Research International CrossRef
  62. Dynamic regulation of EXO1 promotes the progression from liver fibrosis to HCC through TGF-β1/Smad signaling feedback loop
    Mengting Li et al, 2023, Hepatology Communications CrossRef
  63. Silencing long non-coding RNA HNF1A-AS1 inhibits growth and resistance to TAM of breast cancer cells via the microRNA-363/SERTAD3 axis
    Ying Li et al, 2021, Journal of Drug Targeting CrossRef
  64. A joint transcriptional regulatory network and protein activity inference analysis identifies clinically associated master regulators for biliary atresia
    Panpan Sun et al, 2022, Frontiers in Pediatrics CrossRef
  65. The Role of Cytokines in the Different Stages of Hepatocellular Carcinoma
    Noe Rico Montanari et al, 2021, Cancers CrossRef
  66. Tumor Stroma, Desmoplasia, and Stromagenesis
    Arthur Zimmermann, 2017, Tumors and Tumor-Like Lesions of the Hepatobiliary Tract CrossRef
  67. The anti-hepatic fibrosis effects of chlorogenic acid extracted from Artemisia Capillaris Herba on CCl4-induced mice via regulating TGF-β1/smad3 pathway
    Liping Huang et al, 2023, Pharmacological Research - Modern Chinese Medicine CrossRef
  68. Coprinus comatuspolysaccharides ameliorated carbon tetrachloride-induced liver fibrosis through modulating inflammation and apoptosis
    Huajie Zhao et al, 2022, Food & Function CrossRef
  69. Fibroblast growth factor 21 attenuates hepatic fibrogenesis through TGF-β/smad2/3 and NF-κB signaling pathways
    Pengfei Xu et al, 2016, Toxicology and Applied Pharmacology CrossRef
  70. Smad3 gene C‐terminal phosphorylation site mutation aggravates CCl4‐induced inflammation in mice
    Hanyan Ding et al, 2020, Journal of Cellular and Molecular Medicine CrossRef
  71. Mechanistic aspects of antifibrotic effects of honokiol in Con A-induced liver fibrosis in rats: Emphasis on TGF-β/SMAD/MAPK signaling pathways
    Maha G. Elfeky et al, 2020, Life Sciences CrossRef
  72. Effects of FGF21‐secreting adipose‐derived stem cells in thioacetamide‐induced hepatic fibrosis
    Hwansu Kang et al, 2018, Journal of Cellular and Molecular Medicine CrossRef
  73. Curcumin Modulates NOX Gene Expression and ROS Production via P-Smad3C in TGF-β-Activated Hepatic Stellate Cells
    Shahla Asadizadeh et al, 2024, Iranian Biomedical Journal CrossRef
  74. The roles of hepatokine and osteokine in liver-bone crosstalk: Advance in basic and clinical aspects
    Zhanghao Li et al, 2023, Frontiers in Endocrinology CrossRef
  75. Astragaloside IV inhibits hepatocellular carcinoma by continually suppressing the development of fibrosis and regulating pSmad3C/3L and Nrf2/HO-1 pathways
    Chong Zhang et al, 2021, Journal of Ethnopharmacology CrossRef
  76. GP73, a novel TGF-β target gene, provides selective regulation on Smad and non-Smad signaling pathways
    Xiaoli Yang et al, 2019, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research CrossRef
  77. Effect of Quercetin on the Expression of NOXs and P-Smad3C in TGF-Β-Activated Hepatic Stellate Cell Line LX-2
    Narges Mohammadtaghvaei et al, 2021, Hepatitis Monthly CrossRef
  78. A comprehensive review of miR-21 in liver disease: Big impact of little things
    Xinyan Xue et al, 2024, International Immunopharmacology CrossRef
  79. SP1 and UTE1 Decoy ODNs inhibit activation and proliferation of hepatic stellate cells by targeting tissue inhibitors of metalloproteinase 1
    Dong Jia et al, 2016, Cell & Bioscience CrossRef
  80. Matching mouse models to specific human liver disease states by comparative functional genomics of mouse and human datasets
    Kaja Blagotinšek Cokan et al, 2022, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms CrossRef
  81. Lysyl oxidases: linking structures and immunity in the tumor microenvironment
    Paolo Tenti et al, 2020, Cancer Immunology, Immunotherapy CrossRef
  82. Salvianolic acid B exerts anti-liver fibrosis effects via inhibition of MAPK-mediated phospho-Smad2/3 at linker regions in vivo and in vitro
    Chao Wu et al, 2019, Life Sciences CrossRef
  83. SENP2 suppresses epithelial‐mesenchymal transition of bladder cancer cells through deSUMOylation of TGF‐βRI
    Mingyue Tan et al, 2017, Molecular Carcinogenesis CrossRef
  84. Compound Astragalus and Salvia miltiorrhiza extracts modulate MAPK-regulated TGF-β/Smad signaling in hepatocellular carcinoma by multi-target mechanism
    Alex Boye et al, 2015, Journal of Ethnopharmacology CrossRef
  85. The expression dynamics of transforming growth factor-β/Smad signaling in the liver fibrosis experimentally caused by Clonorchis sinensis
    Chao Yan et al, 2015, Parasites & Vectors CrossRef
  86. Class�C1 decoy oligodeoxynucleotide inhibits profibrotic genes expression in rat hepatic stellate cells
    Chun Rao et al, 2019, Molecular Medicine Reports CrossRef
  87. Effect of Quercetin on the fructose-activated human hepatic stellate cells, LX-2, an in-vitro study
    Elham Shakerian et al, 2022, Molecular Biology Reports CrossRef
  88. MiR-27a-3p downregulation contributes to the development of occlusive bronchiolitis
    Ming Dong et al, 2019, Cell Stress and Chaperones CrossRef
  89. Fasciola hepatica Infection in Cattle: Analyzing Responses of Peripheral Blood Mononuclear Cells (PBMC) Using a Transcriptomics Approach
    Andres Garcia-Campos et al, 2019, Frontiers in Immunology CrossRef
  90. Association between malignancies and Marfan syndrome: a population-based, nested case–control study in Taiwan
    Chin-Wang Hsu et al, 2017, BMJ Open CrossRef
  91. Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice
    April K. Marrone et al, 2016, Molecular Carcinogenesis CrossRef
  92. Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity
    Yu Xia et al, 2018, Biomedicine & Pharmacotherapy CrossRef
  93. The Emerging Role of MicroRNAs in NAFLD: Highlight of MicroRNA-29a in Modulating Oxidative Stress, Inflammation, and Beyond
    Hung-Yu Lin et al, 2020, Cells CrossRef
  94. Astragaloside IV suppresses migration and invasion of TGF-β1-induced human hepatoma HuH-7 cells by regulating Nrf2/HO-1 and TGF-β1/Smad3 pathways
    Lili Li et al, 2022, Naunyn-Schmiedeberg's Archives of Pharmacology CrossRef
  95. Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion
    Antonio Vitobello et al, 2019, Life Science Alliance CrossRef
  96. Lonicera japonica Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Mice: Molecular Mechanisms of Action
    Hui Miao et al, 2019, The American Journal of Chinese Medicine CrossRef
  97. TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy
    Ammad Farooqi et al, 2017, International Journal of Molecular Sciences CrossRef