- Anaplastic Lymphoma Kinase (ALK) Rearrangement-positive Lung Cancer with Transformation to Pleomorphic Carcinoma
Yosuke Kamide et al, 2015, Intern. Med. CrossRef - miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1
Hai-Xiang Gao et al, 2016 CrossRef - Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway
HAI JIN et al, 2015 CrossRef - Understanding and targeting resistance mechanisms in NSCLC.
Julia Rotow et al, 2017, Nat Rev Cancer CrossRef - p100 functions as a metastasis activator and is targeted by tumor suppressing microRNA-320a in lung cancer
Aimin Xing et al, 2017, Thorac Cancer CrossRef - MicroRNA-1285-5p influences the proliferation and metastasis of non-small-cell lung carcinoma cells via downregulating CDH1 and Smad4
Shixia Zhou et al, 2017, Tumour Biol. CrossRef - LncRNA ATB promotes proliferation and metastasis in A549 cells by down-regulation of microRNA-494
Yiwei Cao et al, 2018, J. Cell. Biochem. CrossRef - Current Molecular-Targeted Therapies in NSCLC and Their Mechanism of Resistance
Zachary Schrank et al, 2018, Cancers CrossRef - Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?
Venus Sosa Iglesias et al, 2018, Front. Oncol. CrossRef - Hedgehog Signaling in Lung Cancer: From Oncogenesis to Cancer Treatment Resistance
Etienne Giroux-Leprieur et al, 2018, IJMS CrossRef - Apatinib reverses alectinib resistance by targeting vascular endothelial growth factor receptor 2 and attenuating the oncogenic signaling pathway in echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion gene-positive lung cancer cell lines
Yanqiong Chen et al, 2018, Anti-Cancer Drugs CrossRef - null
Francesco Facchinetti et al, 2017 CrossRef - The role of alectinib in the treatment of advanced ALK-rearranged non-small-cell lung cancer
Srividya Srinivasamaharaj et al, 2016, Expert Review of Anticancer Therapy CrossRef - Metastasis manners and the underlying mechanisms of ALK and ROS1 rearrangement lung cancer and current possible therapeutic strategies
Xing Chang et al, 2019, RSC Adv. CrossRef - GNAS-AS1/miR-4319/NECAB3 axis promotes migration and invasion of non-small cell lung cancer cells by altering macrophage polarization
Zhixin Li et al, 2019, Funct Integr Genomics CrossRef - Modalités d’utilisation du ceritinib (Zykadia™), inhibiteur de ALK de 2e génération, dans le cancer bronchique non à petites cellules de stade avancé
Etienne Giroux Leprieur et al, 2015, Bulletin du Cancer CrossRef - Crizotinib resistance: implications for therapeutic strategies.
I Dagogo-Jack et al, 2016, Ann Oncol CrossRef - A tool for discovering drug sensitivity and gene expression associations in cancer cells
Yong Qin et al, 2017, PLoS ONE CrossRef - Mechanistic Understanding of Curcumin’s Therapeutic Effects in Lung Cancer
Wan Nur Baitty Wan Mohd Tajuddin et al, 2019, Nutrients CrossRef - Long non-coding RNA colon cancer-associated transcript-1 regulates tumor cell proliferation and invasion of non-small-cell lung cancer through suppressing miR-152
Na Li et al, 2020, Geriatr. Gerontol. Int. CrossRef - Low expression of miR-192 in NSCLC and its tumor suppressor functions in metastasis via targeting ZEB2
Zhang Yunxia et al, 2016 CrossRef - Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1
Claudia Voena et al, 2016, Oncotarget CrossRef - Targeting hypoxic response for cancer therapy
Elisa Paolicchi et al, 2016, Oncotarget CrossRef - Early and late effects of pharmacological ALK inhibition on the neuroblastoma transcriptome
Shana Claeys et al, 2017, Oncotarget CrossRef - Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
Robert Vander Velde et al, 2020, Nat Commun CrossRef - A bioinformatics investigation into the pharmacological mechanisms of javanica oil emulsion injection in non-small cell lung cancer based on network pharmacology methodologies
Mengwei Ni et al, 2020, BMC Complement Med Ther CrossRef - Notch Transduction in Non-Small Cell Lung Cancer
Amnah Sharif et al, 2020, IJMS CrossRef - Potential monoamine oxidase A inhibitor suppressing paclitaxel‐resistant non‐small cell lung cancer metastasis and growth
Xiaoguang Yang et al, 2020, Thorac Cancer CrossRef - Combining Radiation Therapy with ALK Inhibitors in Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer (NSCLC): A Clinical and Preclinical Overview
Delphine Antoni et al, 2021, Cancers CrossRef - Lung Cancer Management with Silibinin: A Historical and Translational Perspective
Sara Verdura et al, 2021, Pharmaceuticals CrossRef - PRPS2 Enhances Resistance to Cisplatin via Facilitating Exosomes-mediated Macrophage M2 Polarization in Non-small Cell Lung Cancer
Gaohua Liu et al, 2021, Immunological Investigations CrossRef - Knockdown of lncRNA HIF1A-AS2 increases drug sensitivity of SCLC cells in association with autophagy
Ebru Güçlü et al, 2021, Med Oncol CrossRef - Clinical Impact of the Epithelial-Mesenchymal Transition in Lung Cancer as a Biomarker Assisting in Therapeutic Decisions.
Julien Ancel et al, 2022, Cells Tissues Organs CrossRef - Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL
Lucy Hare et al, 2021, Cancers CrossRef - Therapeutic Targeting Hypoxia-Inducible Factor (HIF-1) in Cancer: Cutting Gordian Knot of Cancer Cell Metabolism
Abhilasha Sharma et al, 2022, Front. Genet. CrossRef - The Molecular Role of IL-35 in Non-Small Cell Lung Cancer
Yuqiu Hao et al, 2022, Front. Oncol. CrossRef - Updated Evidence on the Mechanisms of Resistance to ALK Inhibitors and Strategies to Overcome Such Resistance: Clinical and Preclinical Data
Gouji Toyokawa et al, 2015, Oncol Res Treat CrossRef - Research Progress on the Drug Resistance of ALK Kinase Inhibitors
Zhen Li et al, 2022, CMC CrossRef - Anti-migratory effect of curcumin on A-549 lung cancer cells via epigenetic reprogramming of RECK/ matrix metalloproteinase axis
Shabnam Mostofi et al, 2022 CrossRef - Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors
Sara Verdura et al, 2022, Cancers CrossRef -
EML4‐ALK
biology and drug resistance in
non‐small
cell lung cancer: a new phase of discoveries
Mariam Elshatlawy et al, 2023, Molecular Oncology CrossRef - Anaplastic lymphoma kinase inhibitors—a review of anticancer properties, clinical efficacy, and resistance mechanisms
Kajetan Kiełbowski et al, 2023, Front. Pharmacol. CrossRef - Prospective observational study to explore genes and proteins predicting efficacy and safety of brigatinib for ALK-gene rearranged non-small-cell lung cancer: study protocol for ABRAID study (WJOG11919L)
Yuichi Ozawa et al, 2024, Ther Adv Med Oncol CrossRef